1O5U,3BCW,3MYX


Conserved Protein Domain Family
cupin_TM1112-like

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cd02227: cupin_TM1112-like 
Thermotoga maritima TM1112 and related proteins, cupin domain
This family includes bacterial and plant proteins homologous to TM1112, a Thermotoga maritima protein of unknown function with a cupin beta barrel domain. TM1112 (also known as DUF861) is a subfamily of RmlC-like cupins with a conserved "jelly roll-like" beta-barrel fold; structures indicate that a monomer is the biologically-relevant form.
Statistics
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PSSM-Id: 380356
Aligned: 70 rows
Threshold Bit Score: 72.6132
Created: 6-Oct-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
putative active
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:
  • Structure:1O5U: Thermotoga maritima TM1112 binds an unknown ligand; contacts at 4.0A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                     # #    # #                                   #         #    
1O5U_A        32 KWPIWEKEvsEFDWYYd-tNETCYILeGKVEVTTe-dGKKYVIekGDLVTFPkGLRCRWKVl--EPVRKHYNL 100 Thermotoga maritima
3MYX_A       168 RIGVWDSTpyERISRPhkiHELXNLIeGRVVLSLe-nGSSLTVntGDTVFVAqGAPCKWTSt--GYVRKFYAV 237 Pseudomonas syringae p...
NP_251008     49 SAAYFGTTagKFRMTYp-fSEQATVVsGEVRLTDestGQSTLYkaGDSWFVSkGTPVLWEVadgGFVKHYYAV 120 Pseudomonas aeruginosa...
NP_252115     43 ETGIWECTpgRWRRQIv-eQEFCHFLqGRCTFTPd-gGETIRIeaGDALLLPeNSLGVWDVq--ETVRKSYVI 111 Pseudomonas aeruginosa...
NP_353340     74 STAMWDCTagEFRWFFg-wDETVYILeGEVHVTAe-dGSVSILrvGDVAYFRaGTWATWRVd--DYVRKVAFM 142 Agrobacterium tumefaci...
AGW90858      46 RTGLWECTvgSYERQVe-eAEVMHILaGECLFTPa-gGTPIRIkaGDTLFFPaNTTGIWEIl--EPLRKVYVI 114 Ralstonia pickettii DT...
WP_024844620  43 GAGIWECTpgRFRRQVv-qAEYSYIIeGEGSFTAd-gGQPVAFraGDALFFAaDTQGEWDIr--ATVRKAYLI 111 Paracoccus pantotrophus
WP_053554153  46 RLGVWECTpgRWVRQVk-qAEFCHFLsGKAIFTPe-dGEPITLgaGDVAHFPeNSRGVWEIl--ETSRKVFMV 114 Sphingopyxis sp. 113P3
WP_082625604  47 EIGVWESTpgHFARNVa-aQEFCHIIaGECTFTPt-dGEAIHLsaGDAVFFPaATQGIWHVt--KTLRKTYVI 115 Vitreoscilla sp. SN6
WP_086078935  46 RSGVWECQpgTFKRHLa-nAELMHILaGKCTFTPe-gGEPVEFgaGDTVYFPaNTRGVWNVe--TALRKVYAI 114 Bordetella sp. AU7206

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