1Q3T,1CKE


Conserved Protein Domain Family
CMPK

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cd02020: CMPK 
Click on image for an interactive view with Cn3D
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.
Statistics
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PSSM-Id: 238978
Aligned: 91 rows
Threshold Bit Score: 96.7868
Created: 4-Oct-2004
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
CMP-bindingThe sites
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:CMP-binding site
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                     
1Q3T_A     18 QIAIDGPASSGKSTVAKIIakdFGFTYLDTGamyraatymalknqlgveeveallalldqhpisfgrsetgdqlvfvgdv 97  Streptococcus pneu...
Q8ZTJ1      3 VIAVSGQPGSGKTTIAREIarvLGLPLVSSGllfre-------------------------------------------m 39  Pyrobaculum aeroph...
NP_147642  13 VVVISGPPGSGKSTYAKRLaedLGLSYYSTGtifrs-------------------------------------------i 49  Aeropyrum pernix K1
Q9YDD5     13 VVVISGPPGSGKSTYAKRLaedLGLSYYSTGtifrs-------------------------------------------i 49  Aeropyrum pernix
YP_023444   2 RITISGKSGSGKTTVGRLLadkLHYSFISGGyffrk-------------------------------------------k 38  Picrophilus torrid...
NP_971695  15 RIAISGPSGCGNTTVSTLTaktLNLPCINYTfkni--------------------------------------------- 49  Treponema denticol...
NP_280485   2 LVTISGPPGSGKSTVASTLadhLSYEHISGGdifrg-------------------------------------------l 38  Halobacterium sp. ...
Q9HPA5      2 LVTISGPPGSGKSTVASTLadhLSYEHISGGdifrg-------------------------------------------l 38  Halobacterium sali...
Q97BV0      2 RITIAGKIGSGKSTVSQEIskiTGYSVYSSGtffre-------------------------------------------s 38  Thermoplasma volca...
Q9HIT3      2 RITIAGKIGSGKSTVSSELsriTGYTVYSSGtffre-------------------------------------------t 38  Thermoplasma acido...
Feature 1                             #                     ##                                
1Q3T_A     98 dithPIRENEVTNHVSAiaaiPEVREKLVslqqe-iaqqgGIVMDGRDigtvv--lpqaeLKIFLVASvderaerryken 174 Streptococcus pneu...
Q8ZTJ1     40 aarmGMDFIEFHKYAETn---PDIDKKVDslaie-rakagDVVLEGHLtawiv--rpyadVCIYLKASletrarrval-- 111 Pyrobaculum aeroph...
NP_147642  50 arerGLSLAEMSRLAEEd---PRIDLEIDrrtld-vasrgGVVIDSHLaawll--rdkaqYLVLVKAPvwvrvrriar-- 121 Aeropyrum pernix K1
Q9YDD5     50 arerGLSLAEMSRLAEEd---PRIDLEIDrrtld-vasrgGVVIDSHLaawll--rdkaqYLVLVKAPvwvrvrriar-- 121 Aeropyrum pernix
YP_023444  39 aeefNMNLLEFNKYSESh---PEIDYEQDkmllnflknndNIVLESRLssyiaytnnieaFKIYLYASddirykrl---- 111 Picrophilus torrid...
NP_971695  50 akelNISFEEVLRRAQEd---FSFDKTVDkkqie-laeasSCVLGSRLaiwll---nqadLRVYLRASievrakriqk-- 120 Treponema denticol...
NP_280485  39 aedrDLTLAEFNELAEEd---PQIDKDLDrrlretargrdDIVLESRLagwma--geyadIKIWLDAPmsvrarriae-- 111 Halobacterium sp. ...
Q9HPA5     39 aedrDLTLAEFNELAEEd---PQIDKDLDrrlretargrdDIVLESRLagwma--geyadIKIWLDAPmsvrarriae-- 111 Halobacterium sali...
Q97BV0     39 akkmGMSIEDFNRYAETh---PEADYATDgmqkdfmethdNIIVEGRLagwickiysisaFKVFLYATrytrlvrfsn-- 113 Thermoplasma volca...
Q9HIT3     39 arkmNMSIEDFNVYSESh---PEADYYTDetqkafmqandNIIVEGRLagwisylnginaFRIFLYATyytrlvrfag-- 113 Thermoplasma acido...
Feature 1                              #                      
1Q3T_A    175 iakgietdletlKKEIAARDYKDSHRetspl-----kqaedAVYLDTT 217 Streptococcus pneumoniae
Q8ZTJ1    112 ---rdgkslqdaLREVAEREELNRRRylsiygidindlsifDLVLDTS 156 Pyrobaculum aerophilum
NP_147642 122 ---rdgvplrraLAETVEREWSQRLRfkryygidvsdttifHLTVDTS 166 Aeropyrum pernix K1
Q9YDD5    122 ---rdgvplrraLAETVEREWSQRLRfkryygidvsdttifHLTVDTS 166 Aeropyrum pernix
YP_023444 112 -----merdktdILTLNERYRSEILRymefygidynnyiyyDIIIDTD 154 Picrophilus torridus DSM 9790
NP_971695 121 ---reggdiekiKADTDLRDMEDTRRykelygidntkyekaDLIIDTD 165 Treponema denticola ATCC 35405
NP_280485 112 ---redktpaaaRAETEAREESETQRyeeyyaidfdditiyDLSVNTA 156 Halobacterium sp. NRC-1
Q9HPA5    112 ---redktpaaaRAETEAREESETQRyeeyyaidfdditiyDLSVNTA 156 Halobacterium salinarum
Q97BV0    114 ---regieideaAKLLDEREISEKKRyldlygididdlsiyDIVVNTE 158 Thermoplasma volcanium
Q9HIT3    114 ---renididsaRDLMEKREKSEKERyrklygidvddlsiyDIVVNTE 158 Thermoplasma acidophilum

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