Conserved Protein Domain Family
YeiC_kinase_like

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cd01941: YeiC_kinase_like 
YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.
Statistics
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PSSM-Id: 238916
Aligned: 22 rows
Threshold Bit Score: 183.669
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Conserved Features/SitesClick to see Conserved Features Help
 
substrateATP binding
Feature 1:substrate binding site [chemical binding site]
Evidence:
  • Comment:based on homology to other members of the family
  • Citation:PMID 9519409

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                      #                              
NP_296033  75 KVVVVGGANMDLKarvrg----------eavpgTSNPGVtsQSPGGVARNVAENLARLGv----sAALVSAVGPDSLGDV 140 Deinococcus radiod...
CAB52741  392 EVVCVGSVSIDSVlkldnpl-------tskflgTSHPCHseQAFGGVAHNMALASSLMGa----sTKLVSCVGTKSVPTS 460 fission yeast
NP_622014  61 GVTVIGGANIDIKgkpyk----------elrqhTSNPGHinIAPGGVGRNIAHNLAQLNv----pVTFLSVVGNDDEGRR 126 Thermoanaerobacter...
AAM29633  345 KPLVVGASILDLSfkvddqk------rdmkldgATYSAVakQAAGGVGRNIAEGIYKLYg----dVNLISAVGNDQMGQT 414 fruit fly
AAM61339    2 EPVIIGALILDVHakpst----------tpisgTTVPGQvlFAPGGVARNVADCIFKLGi----tPFMIGTLGLDGPANV 67  thale cress
XP_330207 384 DILVAGSVALDLScdyaggvdaqgnktvsplahVSNPSHitQSVGGVGHNVALAAHKVSed--gkVRLCSMVGDDIAGAT 461 Neurospora crassa
EAA62051  334 EILVAGSLAIDLAcdyvpaag-----qttpvsrTSNPAVikQSLGGVGHNVALASSSLGs----sVMFCSVVGDDLSGHA 404 Aspergillus nidula...
CAG80898   19 PLAVVGGVAMDVTcgisg-----------sqlgTSHPGKvtNSIGGVGHNIVLAIHYTGskhgisPRLISAVGQDGDGNE 87  Yarrowia lipolytic...
EAL17731  379 STLVFGSAAVDLTststh----------slaprTTTPGEvfVSPGGVGRNIAEAAQNLLpp--nsVQLVSAYGSVSGSSE 446 Cryptococcus neofo...
XP_451712 355 LSAVIGSVALDTQctfnss---------hiyqgDSNPGKasTSIGGVGHNVALSANYSNrssqhqTTLISAVGKDIAGKH 425 Kluyveromyces lact...
Feature 1                                                                                     
NP_296033 141 LLre----------tEAAGVDvsgvl----rvsgaATGSYTAVLGAGGELll--aVAAMDVMehltp--aalrgLRASLR 202 Deinococcus radiod...
CAB52741  461 SIke---------ylTKSSLQhtive-----ksnfTSCSYTAINDCNGNLll--aGADMAIMenls-----yseIKDDLN 519 fission yeast
NP_622014 127 LLee----------tRQAGVNveqvv----isntrRTGIYLAILNAIGDMdi--aLSGMDILeelni--qylesKTEVIK 188 Thermoanaerobacter...
AAM29633  415 LLqmm-------pkaLKRGLIvad---------nhNTSLCSLIFDKFGDCkl--iLGNMEIHqsita--etlqaHHQLFR 474 fruit fly
AAM61339   68 LLkew--------klSMKGILrre---------diSTPIVSLVYDTNGEVaagvaGVDAVENfltpe---wiqrFEYNIS 127 thale cress
XP_330207 462 ILan----------lESSGLDttcirklgreypstRTAQYVAVNDADKNLvm--aMADMAIFsnhs----fptyWNSAVA 525 Neurospora crassa
EAA62051  405 ALtflq-----qenlPTSGVKvlpa------ssgaRTAQYVAVNDATRDLhv--aMADMGILqlpaetldfdsfWEPVVS 471 Aspergillus nidula...
CAG80898   88 ILsh----------mEKVGLDtsgik----qdskeGTARYVAMHDKNGDLvv--aCADMDIIqnld-----vvhIGQQLT 146 Yarrowia lipolytic...
EAL17731  447 SDttepdafgklllfELAGANmradgl--vgkegrNTAVCSLTLEKDGDLva--gVADMGIVetlt-----eefVARKID 517 Cryptococcus neofo...
XP_451712 426 ILsg---------lgMSADGIyin--------eseRTAQYISIHSRDGELyi--aGSDMDIVtqlp-----ikhITNKLK 481 Kluyveromyces lact...
Feature 1                                                                                     
NP_296033 203 GAawv--vaDGNLPAdtLPTLLALAaet---gvrVVYEPVSVPKaarlrp------------alaaghVPYAVTPNLaEL 265 Deinococcus radiod...
CAB52741  520 DAkyi--cfDGNISPslMLDITTSKssk----qrVVFEPTSGPKtlkilk-------------vlsvaSIDFITPNKfEL 580 fission yeast
NP_622014 189 NSeiv--vfDANIPEesIRYITELCynnnipvvvEPVSIDKAKKlkn------------------vldKIDYITPNKeEL 248 Thermoanaerobacter...
AAM29633  475 EApli--imDSNISEqaMASILQQAqin---kipVFFEPTDMFIagkpfkl-----------lpeltkNIRLIKPNMqEL 538 fruit fly
AAM61339  128 SApll--mvDANLSSlaLEASCKLAaes---svpVWFEPVSVTKsqria---------------siakYVTIVSPNQdEL 187 thale cress
XP_330207 526 ATkpkwlvvDGNWAEadIQTWIEAGrkh---garVAFEPVSAAKserlfaapkqg--gqlplrlfpnaSVDLASPNQyEL 600 Neurospora crassa
EAA62051  472 RAkpqwvmvDANWSPelLSKWVAAAnkh---garVAFEPVSTAKsqflfkkgpereaavgesacvpnnTVSLATPNEfEL 548 Aspergillus nidula...
CAG80898  147 TAqpkwimmDGNIGLeaKKEVLKYArdk---saqVAFEPTSVPKaaalseln---------lpvypnnSIALATPNTaEL 214 Yarrowia lipolytic...
EAL17731  518 EEkpemvvfDLNLLEgvVKAILTACqtl---nvpTFCDPTSTPKlpr------------------lipALNILLPSSpSF 576 Cryptococcus neofo...
XP_451712 482 SLkpnvvlvDANVSVevLEHLITLRekm---gfkLIFEPTSECKaqkiaqak--------nlkvypnhGFDLITPTVtEL 550 Kluyveromyces lact...
Feature 1                                                                                     
NP_296033 266 AALVGRevadspaaire-------------------------------------aalelhalgaeLVWVRRgerGSVLSl 308 Deinococcus radiod...
CAB52741  581 DVLFQAmkdgnffeneswwqklnsfgitssfynei-erftkstgieeitengilqkcfhllpfikNIIVKLgpnGALLIs 659 fission yeast
NP_622014 249 ESITEIkilddedmkka--------------------------------------vkylrdkgikNVIVTLgerGVYVSs 290 Thermoanaerobacter...
AAM29633  539 KTITEAitgetvkwnpetkqpqte------------------------lvqqakslikkidsrfnCIIATLsdhGVLLSy 594 fruit fly
AAM61339  188 IAMANAlcaknlfhpfrsdenklsie--------------------dmfralkpailvllkngvkVVIVTLgsnGALLCs 247 thale cress
XP_330207 601 SAMHAAatrneyfthswfevidtfgmhgsrdk-------fvrltsaeitdmglpqqniqllpyipTIITKLgakGALVTm 673 Neurospora crassa
EAA62051  549 AAMYTAarenglfetagwwrvidamgmtssgsre----rlvamtsaalvdegipqqsiqllpflpCIITKLgarGALLTq 624 Aspergillus nidula...
CAG80898  215 EAMFEAfhekgrfdvddwfpvidglalgadfrngatmlshqhrglkaileqgtlaqaihmlpyipTLIIKGganGVVVFq 294 Yarrowia lipolytic...
EAL17731  577 PRPLTHlt-------------------------------------------------------pnLLELDLl--HSLLSs 599 Cryptococcus neofo...
XP_451712 551 KGIYEAldknnkfdldnwfpvldsfkidrnlsvn---kkastgelkylldngifqtasfllpyfpRMVIKHgskGIYIFs 627 Kluyveromyces lact...
Feature 1                                                                         #  #        
NP_296033 309 ----------------------------------------pDESHElpa----------lpaAVVDVTGAGDAMLAAFLA 338 Deinococcus radiod...
CAB52741  660 seklqgvns----------------------nsaslftpgnVTVKYypvp--------kviaTPVNASGTGDTFIGTFTA 709 fission yeast
NP_622014 291 e---------------------------------------eLEKFIepy-----------qtEIVDATGAGDALTAGLVY 320 Thermoanaerobacter...
AAM29633  595 rgdaendarl---------------------lldvskptppHSTRFypap---------mvhNIVNVSGAGDSFCAGFIT 644 fruit fly
AAM61339  248 kgnpkkalnidrkflrsgevfkrvqsvcspnrfselgsnrsLFAMHfpt----------ipaKVKKLTGAGDCLVGGTVA 317 thale cress
XP_330207 674 llkpgdpllkdshha----------pyilarnyndhphvggVYMRLfppv--------etvkDVVSVNGVGDTFLGVLVA 735 Neurospora crassa
EAA62051  625 llkpgdsrltdpeys----------pyilsrtvstgdliggVYMRLfppaa------kltddAIISVNGAGDTLLGVIIS 688 Aspergillus nidula...
CAG80898  295 liddiesaihsqrsasnk-----tpglfqkgnaasgntkvgVYMQYfepee-------vgsqSIVSVTGAGDTLFGTLAM 362 Yarrowia lipolytic...
EAL17731  600 sas----------------------------------ddtsSITWEfinslgldgdwrakveRFTNVNGREWINVNGVVQ 645 Cryptococcus neofo...
XP_451712 628 mekdtdpatleliskysd-----ysmyctgehvggqqqgvlVEHHAvpa----------gntTVTSVTGAGDTLVGILLN 692 Kluyveromyces lact...
Feature 1                                       
NP_296033 339 GLVAGl---------tPLHAAREGHAAAALTVES 363 Deinococcus radiodurans R1
CAB52741  710 LLSKGw---------gMDDAIDTAQKAAGLTLQC 734 fission yeast
NP_622014 321 GIFNGy---------sLEVSAKLGLAAASLTISS 345 Thermoanaerobacter tengcongensis
AAM29633  645 ALLRGr---------sLDECIAGGFVAAERALQS 669 fruit fly
AAM61339  318 SLSDGl---------dLIQSLAVGIASAKAAVES 342 thale cress
XP_330207 736 GLAMGg---------rVENLVDVAQRAACLSLRS 760 Neurospora crassa
EAA62051  689 GLASGhgr-----vedNATCSFFAYNRHSLDGVL 717 Aspergillus nidulans FGSC A4
CAG80898  363 EIVKDeswln-dmgdkKSAVVSRAMNNAVKTIQS 395 Yarrowia lipolytica CLIB99
EAL17731  646 KMVSC-----------LPYVASFWVKAGQRGLLH 668 Cryptococcus neoformans var. neoformans B-3501A
XP_451712 693 EISIDpeflelkdparRKHRLDRAQYGARITLED 726 Kluyveromyces lactis NRRL Y-1140

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