Conserved Protein Domain Family
cyclophilin_WD40
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cd01927: cyclophilin_WD40 
cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.
Links
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Statistics
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PSSM-Id: 238908
Aligned: 9 rows
Threshold Bit Score: 276.265
Created: 13-Oct-2004
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Conserved Features/SitesClick to see Conserved Features Help
 
active site
Feature 1:active site [active site]
Evidence:
  • Comment:Based on similarity to related proteins with known structure and function.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                            ##    #                                  
CAB88542  477 IMHTTLGDIHMKLYPEECPKTVENFTTHCRNGYYDNHLFHRVIRGFMIQTGDPLGDGTGGQSIWGREFEDEfhksLRHDR 556 thale cress
AAK93333  485 VLHTTKGDIHMRLFFKEVPKTVENFCVHAKNGYYNGHIFHRVIKGFMVQTGDPTGTGTGGKSIWGSDFKDEfvpsLKHDR 564 fruit fly
NP_587769 458 IIHTTQGDISIKLYPEEAPKAVQNFTTHAENGYYDNTIFHRIIKNFMIQGGDPLGDGTGGESIWKKDFEDEispnLKHDR 537 fission yeast
BAC78591   29 VMHTSMGDIHLRLYPEECPKTVENFTTHCRNGYYDNLIFHRVIKGFMIQTGDPLGDGTGGQSIWGREFEDEfhksLRHDR 108 Japanese rice
XP_330469 484 VIHTTYGDIHIRLFPDAAPKAVENFVTHAKRGYYNNTIFHRVIRKFMIQGGDPLGDGTGGESIWGKEFEDEfs-sLKHDK 562 Neurospora crassa
EAK90537  626 ILHTTKGDITLELYPEIAPKACENFSVHCFNGYYNNCIFHRVIKGFMIQTGDPTGQGIGGVSIWGKEFEDEispnVKHDE 705 Cryptosporidium pa...
YP_008132   8 QIETTQGTIEVALRPDVAPKATENFIKHAKDGYYNGVIFHRVIKGFMIQGGDPTGTGRGGESIWNKPFEDEvsdnVKFDR 87  Parachlamydia sp. ...
EAL22515  507 TIHTTKGDISVQLFPDEAPKTVENFITHARNGYYNGTIFHRIIKKFMIQGGDPFGDGTGGESIWGGTFEDEisprLRHDR 586 Cryptococcus neofo...
XP_424751 474 IIHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHIFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEfhstLRHDR 553 chicken

Feature 1                     # #       #                                          
CAB88542  557 PFTLSMANAGPNTNGSQFFITTVATPWLDNKHTVFGRVVkGMDVVQGIEkvkt-dknDRPYQDVKILNV 624 thale cress
AAK93333  565 PYTVSMANAGPNTNGSQFFITVLPTPWLDNKHTVFGRVYrGMEVVLNICnskanpktDKPYDDIKIISI 633 fruit fly
NP_587769 538 PFTVSMANSGPNTNGSQFFITTDLTPWLDGKHTIFARAYaGLDVVHRIEqget-dkyDRPLEPTKIINI 605 fission yeast
BAC78591  109 PFTLSMANAGPNTNGSQFFITTVATPWLDNKHTVFGRVVkGMDVVQQIEkvkt-dknDKPYQDVKILNV 176 Japanese rice
XP_330469 563 PYTVSMANAGPNTNGSQFFITTEKTPWLDNKHTIFGRGVqGLDVIHRIEnvk--thkDKPVEDIKILNI 629 Neurospora crassa
EAK90537  706 PFTLSMANAGPNTNGSQFFITTASCPWLDGVHTIFGKVVhGKEIVKEIEhvst-nrnDRPIQDVSIISA 773 Cryptosporidium parvum
YP_008132  88 PGLLAMANAGPKTNGSQFFITTAATPWLNKKHTIFGEIIkGYDVVQKIEntqt-gpgDRPVEEQKIINI 155 Parachlamydia sp. UWE25
EAL22515  587 PYTLSMANAGPGTNGSQFFITTVPCQWLDGKHTVFGRAVgGLDSVDAIEdakt-dknDRPFEDISISSI 654 Cryptococcus neoformans var. ...
XP_424751 554 PYTLSMANAGPNTNGSQFFITVVPTPWLDNKHSVFGRVTkGMEVVQRISnvkvnpktDKPYEDISIINI 622 chicken

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