Conserved Protein Domain Family
sialate_O-acetylesterase_like1
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cd01827: sialate_O-acetylesterase_like1 
sialate O-acetylesterase_like family of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.
Links
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Statistics
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PSSM-Id: 238865
Aligned: 6 rows
Threshold Bit Score: 294.737
Created: 24-Aug-2004
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Download Cn3D
 
Feature 1:active site [active site]
Evidence:
  • Comment:by similarity to other members of this super-family
  • Comment:the active site resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases
  • Citation:PMID 7773790
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1             #                                #                                      
BAC56898   23 VKVACVGNSITYGytlpnpatdsYPSQLQQLLGETYEVGNFGKSGATLLnkghrpym-------------qqeefkkaIA 89  Bacteroides fragil...
AAO76299  272 VRVACIGNSITFGagirnrsrdsYPSVLARMLGDSYWVKNFGVSARTMLnkgdhpym-------------nepayknaLA 338 Bacteroides thetai...
AAO76850   24 IRVATVGNSITGGtnd----ygyYAMPLAEMLGDDYEVTKFGKGSSGVFiklredattpenpneyqfayinseqcaaaLE 99  Bacteroides thetai...
AAO79183   33 IKIACIGNSITEGad-------nYPTPLARMLGNQYEVGNFGKWGHTLLrkgdhpym-------------stdafinaQK 92  Bacteroides thetai...
CAH09765   25 IKIACIGNSITYGvgtrnpakdsYPAVLGQMLGDGYEVRNFGVSARTMLmkgdhpym-------------keeryrqaLA 91  Bacteroides fragil...
AAO77728   21 IKVACVGNSITENials--neqkYPSILQDLLGNGYIVRNYGIGARTVLkkgdypyw-------------neerykevLA 85  Bacteroides thetai...

Feature 1                 #                                                                   
BAC56898   90 FAGDIVVIHLGINDtdprdw-pnyrdSFVKDYLALIDSFrvanPKCHIIIARLTPIADRHprf--esgTRDWHGEIQQSI 166 Bacteroides fragil...
AAO76299  339 FNPNIVVIKLGTNDsksfn--wkykaDFMKDAQTMIDAFkglpSQPKIYLCYPSKAYLTGdg----inDDIISKEIIPMI 412 Bacteroides thetai...
AAO76850  100 YKPNIVIIKFGANDankknfekygkeTFKADYKKLIAKFqalsTKPDIYICTPPPMYYGDggflgsfdDNVAKNYIQPAV 179 Bacteroides thetai...
AAO79183   93 FQPNVVIIKLGTNDskpen--wkykdEFETDLEYMISTFqkcgSKPKIIICRCIPASNNLyg----irNEIIKDEIYPIQ 166 Bacteroides thetai...
CAH09765   92 YNPDIVTIKLGTNDtkpqn--wryksDFKKDMETMIRTIralpSKPEIYLCYPIPAYAVQwg----inDSTIVHGVMPVI 165 Bacteroides fragil...
AAO77728   86 WNPDIVIVKMGTNDakaqn--waykdNFESDYIEFILSFqtlpSHPKVFICYPIPTFKDNflp---veDQLLVKEMMPMI 160 Bacteroides thetai...

Feature 1                                  #  #                  
BAC56898  167 etiakyAGVQLMDFHEPLypyp---yllpDAVHPNVEGAGILAKTVYSAIT 214 Bacteroides fragilis YCH46
AAO76299  413 kklakkNDLSVIDLHTAMdgmp---elfpDRIHPNEKGAQVMAKAVYQSIS 460 Bacteroides thetaiotaomicron VPI-5482
AAO76850  180 reiaeeLNLVCVDLYNPLkghpefmpggnDWVHPDHRGHYIIAKEVYKAIT 230 Bacteroides thetaiotaomicron VPI-5482
AAO79183  167 kkvarkFHLKLVDLYSPLehkvdstcyvwDNVHLNKSGSLILAEHIYKAIT 217 Bacteroides thetaiotaomicron VPI-5482
CAH09765  166 dqlaakYRLKVIDLHTPLtgmk---ecfaDHVHPNEKAAARIARVIYRQLT 213 Bacteroides fragilis NCTC 9343
AAO77728  161 dniskaTCADIIDLHTPLvgkd---dcvyDKVHPNEKGTKIMARVIARKIC 208 Bacteroides thetaiotaomicron VPI-5482

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