Conserved Protein Domain Family
EF2_IV_snRNP
?
cd01683: EF2_IV_snRNP 
EF-2_domain IV_snRNP domain is a part of 116kD U5-specific protein of the U5 small nucleoprotein (snRNP) particle, essential component of the spliceosome. The protein is structurally closely related to the eukaryotic translational elongation factor EF2. This domain has been also identified in 114kD U5-specific protein of Saccharomyces cerevisiae and may play an important role either in splicing process itself or the recycling of spliceosomal snRNP.
Links
?
Statistics
?
PSSM-Id: 238840
Aligned: 24 rows
Threshold Bit Score: 214.461
Created: 23-Jul-2004
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
CAA22126   670 DPVARFCETAVDTSsiKCFSDTPNKk--------NRITMVVEPLEKg-ISNDIENGKVNINWpqkr-------------- 726  fission yeast
P36048     672 DPLTVFSESCSNESfaSIPVSNSISrlgeenlpgLSISVAAEPMDSk-MIQDLSRNTLGKGQncldidgim--------- 741  baker's yeast
AAS52561   623 MPLVKFSEGCSDTSfaAIPVSSPDGk--------IKLVISAEPLQQe-LIRDLTRGKLVSSElqdmk------------- 680  Ashbya gossypii ...
EAK88970   723 DPMVHFCETVLEKSvvKCFGDSTNGl--------NRLYITSEPLDRg-ISDELENGIMKVSIsdtkdp------------ 781  Cryptosporidium ...
CAG62682   662 DPVTVFAESCQGESfaAIPVESSNHn--------ISLTVCAEPLDKk-IVQDISKKKLDVELlgdkkg------------ 720  Candida glabrata...
CAH02886   614 QPLVQFTESCQNESfaSIPVKSNNGv--------VSLSVMAEKLDGk-IVHDLTHGEIDSSElnnmr------------- 671  Kluyveromyces la...
CAG89055   672 DPMTRFSETCIDTSvtKISAKSSSGn--------NSISIISEPVDDsrLSLAIENGKINLSQplkt-------------- 729  Debaryomyces han...
CAI76219   904 DPVVKFSETITESTslITFTHTNNLk--------NKLYMISQPLESn-ISTLLDSTIGVNSIrldsglngmglnggldsm 974  Theileria annulata
XP_656614   40 DPCVIFNETVSCLSqmKSVALSTNHr--------NRIAVIIDPLDEn-TIKGIEKGELKEEKgr---------------- 94   Entamoeba histol...
CAJ08747   718 QPFVTFAETVQDAE--GLLAMTGTRn--------NSVGFVSGALPRt-FTQAIEYEQLRLFSteldedr----------- 775  Leishmania major

CAA22126   727 --------------------iseFFQKNYDWDLLASRSIWAFgp-ddRGTNILRDDTLSTDVdknvLNSVKEYIKQGFQW 785  fission yeast
P36048     742 ---------------dnprklskILRTEYGWDSLASRNVWSF-----YNGNVLINDTLPDEIspelLSKYKEQIIQGFYW 801  baker's yeast
AAS52561   681 -------------------tlarKLRNDYGWDSLAARSVRSF-----HNCNVFLDDTLPDEVdkglVNAVMRHILQGFKW 736  Ashbya gossypii ...
EAK88970   782 ------------------kyygnLLAEKYGWDKLAVKSLWAFgpdpsIGSNVLLDDTSSITVdkklLYDVKDDIIQGFNW 843  Cryptosporidium ...
CAG62682   721 -----------------lremakVLRRDYGWDSLAARNIWAF-----FHTSILVDDTLPDETdknlLQHFREQVLQGFYW 778  Candida glabrata...
CAH02886   672 -------------------kfskRLRTEYGWDSLAARNCWDL-----SKCNVFIDDTLPDETdkqlLKKYKENILQGFEW 727  Kluyveromyces la...
CAG89055   730 --------------------tskILRKEYGWDALSARSVWCFgpedlHNPSILIDDTIEGETdkklLYSLKDSISLGFKW 789  Debaryomyces han...
CAI76219   975 glngvnrgvyrgvgmssmgmsglDMELNKEWDILDIKNVWSFg---nGIPDVLINDTIPNEVdinlLNHIKSSIIQGFQW 1051 Theileria annulata
XP_656614   95 ---------------------deILYKKYQWDILASKSLLCIgp-eeKIPNVLLNDILEEEKre-kINEMKEACCIGFKW 151  Entamoeba histol...
CAJ08747   776 ----------------qprklwtILRRDYGFDALDAQHVLAAgpdgtKGPSILIDDTLAEEAhhplKAAHQRAVVSAFRS 839  Leishmania major

CAA22126   786 GTREGPLCDETIRNVNFRLMDVVLAPeq---------------------iYRGGGQIIPTARRVCYSSFLTASPRLMEPV 844  fission yeast
P36048     802 AVKEGPLAEEPIYGVQYKLLSISVPSdv--------------------niDVMKSQIIPLMKKACYVGLLTAIPILLEPI 861  baker's yeast
AAS52561   737 ALREGPLAEEPIYGVQFKLLDLQIEGd----------------------hSSSSIQLVALVRRACYIALLTAVPVILEPI 794  Ashbya gossypii ...
EAK88970   844 AVKEGPLLEEPIRNVKFKILDVNLSSdk---------------------vSRGTGQIVPASRRACYTSMFLASPKILEPI 902  Cryptosporidium ...
CAG62682   779 AVREGPLMEEAIHGVKFRILKFEMSGrvnld---------------sldvGIIGVQLIPLMRKACNVALLTAKPIVVEPI 843  Candida glabrata...
CAH02886   728 AVKEGPLADETIHACQFKLLQFKVQEds--------------------ieDIIPSQLVPMTRKACYIALMSATPIIMEPI 787  Kluyveromyces la...
CAG89055   790 SVNEGPLCDEPIRNTKFKILDAVISGse---------------------iQRSGTQIIPMTRKACYTGFLTSSPRLMEPI 848  Debaryomyces han...
CAI76219  1052 AIKEGPLIEEHIRYCVTVLATAAPISpltstvtpnvkfrlincelsneyiNITPGQIIPATRRLCYSSFLLSTPRLMEPI 1131 Theileria annulata
XP_656614  152 AMSSGPLCEEEMRNCRVRIIDAEFER------------------------NVDEQQVIQALRRSIYAGIILSSPQLLEPI 207  Entamoeba histol...
CAJ08747   840 TMAAGPLVGEMVRGVAAKLIFADIDA------------------------STRDAVVLSNARTALRHSLFGARPRLMEPV 895  Leishmania major

CAA22126   845 YMV 847  fission yeast
P36048     862 YEV 864  baker's yeast
AAS52561   795 YEV 797  Ashbya gossypii ATCC 10895
EAK88970   903 SLV 905  Cryptosporidium parvum
CAG62682   844 YEM 846  Candida glabrata CBS138
CAH02886   788 YEV 790  Kluyveromyces lactis NRRL Y-1140
CAG89055   849 YTV 851  Debaryomyces hansenii CBS767
CAI76219  1132 LFS 1134 Theileria annulata
XP_656614  208 YVV 210  Entamoeba histolytica HM-1:IMSS
CAJ08747   896 MAV 898  Leishmania major
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap