Conserved Protein Domain Family
AcnX_swivel
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cd01356: AcnX_swivel 
Putative Aconitase X swivel domain. It is predicted by comparative genomic analysis. The proteins are mainly found in archaea and proteobacteria. They are distantly related to Aconitase family of proteins by sequence similarity and seconary structure prediction. The functions have not yet been experimentally characterized. Thus, the prediction should be treated with caution.
Links
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Statistics
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PSSM-Id: 238658
Aligned: 18 rows
Threshold Bit Score: 104.711
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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substrate
Feature 1:substrate binding site [chemical binding site]
Evidence:
  • Comment:These residues participate in the active site of the catalytic domain.
  • Comment:Based on related sequences with known structures.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                   ###                
NP_249950   12 LVAGSASGELLYAPTg----LSFWGGVDPRSAevid---rhhPLSGRHLHGRLLAiPGGRGSCTGSSVlLELILGGRAPA 84   Pseudomonas aeru...
Q9YA49       7 RSRPIVGGEAEGPAVvi-dsLSFYGEVDPETGv---------TSGGKPLAGRVAAiRRSRGSTVGSYViYALKENGVAPL 76   Aeropyrum pernix
NP_103254   17 QLAGEADGLALVFSQp----LSFWGGIDAETGdiid---hshPGLGQNVAGRILVmPSGRGSSSSSSVlAEAIRRGTAPA 89   Mesorhizobium lo...
NP_355982   16 ILAGAAEGKVIATTEa----LSFWGGVDPATGkvid---vhhPLHGICLTGGVLFmPTSRGSCTGSGVlLDLILTGRAPS 88   Agrobacterium tu...
NP_559867    7 KGRGRVRAEVVKITSp----VSLLGDLDPEAG----------KLAGVDVVGKIAAlPYVKGSTVGPYVlWGAARRGKAPL 72   Pyrobaculum aero...
NP_879485   16 EGQALVMREGFSPRYd----LDRWSGVISRIGh---------SAEGESIKDRILViPTAKGGVAGGWAfYDLLHKGIAPK 82   Bordetella pertu...
NP_881235   13 SLPDKVVGEALVSNDa----ISMRYDVDASTGkvvr---pshDLYGQSISGKVLIfKNTKGGVATGWAlLNLKSRGTAPI 85   Bordetella pertu...
EAA60663     8 IVHGAATGEILYSKVp----LSFWGGVEQTTGdiid---hhhPLFGENIKDRVLVlPSTRGSCSGSLVlIELLVNRVAPT 80   Aspergillus nidu...
NP_972806    9 IVPGTVSAEALVSSQgfntlASFQKALMFGDKkahcsdqnnlDLYKKEIAGKALClPQTIGSTTGGMViFCAASMGRQPA 88   Treponema dentic...
XP_385227   14 YVQGRASAKLLASNLe----LSFWGGVDPQTSevid---rhhTLSGKHLQNTILAiPGGRGSCTGSGImLELLLNGKAPE 86   Gibberella zeae ...

Feature 1                                                                    
NP_249950   85 AILlr-epDEILALGAIVAEELFGRSLPIAc---------LGERFd----------ELAAYP 126  Pseudomonas aeruginosa PAO1
Q9YA49      77 AILme-raEPIVIAGCVLAGIPLYDGLPPEff------erVRDGYrvrvh-sdglvEVLGPG 130  Aeropyrum pernix
NP_103254   90 GILle-rpDPILAVGAIVAEFLYDIHMPLV----------VCDIA-----------GIASGD 129  Mesorhizobium loti MAFF303099
NP_355982   89 ALVfc-eaEDVLTLGALVAAEMFDKALPVIrldae-tfsrFSRAAhvs-----idqNTIKAD 143  Agrobacterium tumefaciens str. C58
NP_559867   73 AIVaqkpdLMLISACVLAGIPLFQGVLEEG----------CVNIDl----------ETGAYD 114  Pyrobaculum aerophilum str. IM2
NP_879485   83 ALVfg-klNPVMVQGAVLAGMPIMEGFDARl---------LQAIAs---------gAALRLD 125  Bordetella pertussis Tohama I
NP_881235   86 ALVcd-ttNPVFVQGAALAGLPIMDGFRESpr------saVRTGDvveldgisgelKVLRRG 140  Bordetella pertussis Tohama I
EAA60663    81 ALVfw-dsEAIVTTGVIVARTLLGLSLPVYrvs----qgqFEDIEnqkyl-svrgpELLTSD 136  Aspergillus nidulans FGSC A4
NP_972806   89 CMLfsepiDSLAAAGVILAANFTDNSIPTVdnlgkeflaaVKSGSrvqv---kengEVIIED 147  Treponema denticola ATCC 35405
XP_385227   87 AIIfe-rrEDILTLGVMIAEEVFQQSIPVLv---------LKKEDf---------rQLLKLD 129  Gibberella zeae PH-1

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