Conserved Protein Domain Family
INT_FimBE_like
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cd01197: INT_FimBE_like 
FimB and FimE and related proteins, integrase/recombinases.
This CD includes proteins similar to E.coli FimE and FimB and Proteus mirabilis MrpI. FimB and FimE are the regulatory proteins during expression of type 1 fimbriae in Escherichia coli. The fimB and fimE proteins direct the phase switch into the 'on' and 'off' position. MrpI is the regulatory protein of proteus mirabilis fimbriae expression. This family belongs to the integrase/recombinase superfamily.
Links
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Statistics
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PSSM-Id: 271197
Aligned: 4 rows
Threshold Bit Score: 312.905
Created: 17-Jun-2013
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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active site
Feature 1:active site [active site]
Evidence:
  • Comment:The catalytic residue tyrosine is surrounded by three basic residues at the active site
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                             #                                       
P0ADH8      1 MSKRRYLTGKEVQAMMQAVcyGATGARDYCLILLAYRHGMRISELLDLHYQDLDLNEGRINIRRLKNGFSTVHPLrFDER 80  Escherichia coli
ELG55342    1 MKQRKYLTQSEVELLLAEArrSSTPERDRCLLYMSFIHGFRVSEVCALRLTDVSLQDRCLHIKRMKNGFSTIHPIqNDEA 80  Escherichia coli K...
NP_052162   1 MKERKHLVSAEVDRLIEAAgrSRNSARDRCLLLLMFRHGLRVSEACGLQLSQVDAESRVLHVSRLKKGLSTTHPLrTDEL 80  Chlorobium limicola
CAB61438    1 MKQRKFLTRFEVNAILKQAkeGRYPERDYCMFLMCFLHGFRVSELCNLTLSDIDLESRILYVRRLKGGLSTTQPIiDEEY 80  Proteus mirabilis

Feature 1                                                            #  ##                    
P0ADH8     81 EAVERWTQERanwkgadrtdaiFISRRGSRLSRQQAYRIIRDAGieAGTVTQTHPHMLRHACGYELAERGaDTRLIQDYL 160 Escherichia coli
ELG55342   81 RILKAWLKVRrslpga-esqwlFVSRQGGGLTRQRVWQVIKHLGkqAGIDVHSHPHMLRHACGFALADRGvDTRLIQDYL 159 Escherichia coli K...
NP_052162  81 KAIRAWLAIRakmkp--dtddfFLSNRRGPLSRKTAWLAIRKYGelAGLPLPAHPHMLRHACGFALADQGaDTRLIQDYL 158 Chlorobium limicola
CAB61438   81 EALCNWLKSRenwres-dsewvFLSQKTGPISRQQVYGLLRRLGkkANVSISPHPHMLRHACGYALADLGrDTRLIQDYL 159 Proteus mirabilis

Feature 1               #           
P0ADH8    161 GHRNIRHTVRYTASNAARFAGL 182 Escherichia coli
ELG55342  160 GHRNIRHTVIYTASNVERFRNI 181 Escherichia coli KTE115
NP_052162 159 GHRNIQHTVIYTAANPARFERL 180 Chlorobium limicola
CAB61438  160 GHRNISHTVIYTASNSKRFINM 181 Proteus mirabilis

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