Conserved Protein Domain Family
IPT_plexin_repeat3
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cd01181: IPT_plexin_repeat3 
Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
Links
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Statistics
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PSSM-Id: 238586
Aligned: 10 rows
Threshold Bit Score: 108.658
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_039393  519 PTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHgg------------------------------kEHInICEVL 568  human
NP_524616 1097 PRIMQIKPLRSFKSGGRVLTVHGIYLNSIQKPELEVFYdne----------------------------rvNKT-SCVVI 1147 fruit fly
BAA32308  1110 PRVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFng------------------------------kESVnVCKVV 1159 human
BAA31595  1129 PVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHig------------------------------rEPT-LCKVL 1177 human
CAB57274  1026 PTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRAKYgg------------------------------iEREnGCLVY 1075 human
I51553    1038 PTVQKIEPEWSIASGGTPLIVTGMNLATIKEPKIRAKYgd------------------------------vEKEnNCTLY 1087 African clawed frog
P51805    1023 PTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYrg------------------------------iETTnTCQVI 1072 human
P08581     742 PIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVhea---------------------------grnFTV-ACQHR 793  human
JC5148     736 PSVSSIKPVKSFLSGGSSITAYGKNLNAVASPLMVIHLskl---------------------------evsYNM-SCIHR 787  African clawed frog
CAB56222  1069 PNITSAGPTKSFLSGGREICVRGQNLDVVQTPRIRVTVvsrmlqpsqglgrrrrvvpetacslgpscssqqFEE-PCHVN 1147 human

XP_039393  569 Na-TEMTCQAPALalgpdhqsdlteRPEEFGFILdnvq--------------sllILNKTnFTYYP 619  human
NP_524616 1148 Ns-NQMECPSPPVnykfet-fkktnRKMDTELHLqnssfqtetrykneydrkkrrADFGDtFRLYT 1211 fruit fly
BAA32308  1160 Nt-TTLTCLAPSLttdyrpgldtveRPDEFGFVFnnvq--------------sllIYNDTkFIYYP 1210 human
BAA31595  1178 Ns-TLITCPSPGAlsn-------asAPVDFFINGrayadevava-eelldpeeaqRGSRFrLDYLP 1234 human
CAB57274  1076 Nd-TTMVCRAPSVanpvrsppelgeRPDELGFVMdnvr--------------sllVLNSTsFLYYP 1126 human
I51553    1088 Nd-TTMVCLAPSVdnplrsppengdRPDEIGFIMdnvh--------------allIVNTTsFLYYP 1138 African clawed frog
P51805    1073 Nd-TAMLCKAPGIflgrpqpraqgeHPDEFGFLLdhvq--------------tarSLNRSsFTYYP 1123 human
P08581     794 SnsEIICCTTPSLqqlnl--qlplkTKAFFMLDGi--------------------LSKYFdLIYVH 837  human
JC5148     788 StsELIWCSTPSLkelnl--eppitTRVFFILDGv--------------------ISNNFeLSYVN 831  African clawed frog
CAB56222  1148 Ss-QLITCRTPALpglp----edpwVRVEFILDNlvf---------------dfaTLNPTpFSYEA 1193 human
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