Conserved Protein Domain Family
IPT_plexin_repeat2

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cd01179: IPT_plexin_repeat2 
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.
Statistics
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PSSM-Id: 238584
Aligned: 23 rows
Threshold Bit Score: 99.9912
Created: 10-Jan-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_309509  891 VRLEGLSPTMGPQSGGTKLSIIGKHLNVGTa--aIAYLDDYECRInrtqasssRLTCVTSAArspehiRVLTLRIDGanr 968  Anopheles gambia...
NP_002664 1162 PKVHSIFPARGPRAGGTRLTLNGSKLLTGRlediRVVVGDQPCHLlpeq-qseQLRCETSPRptp-atLPVAVWFGAte- 1238 human
BAA86520   930 PVLLSLSPRWGPQAGGTQLTIRGQHLQTGGn--tSAFVGGQPCPIlepv-cpeAIVCRTRPQaap-geAAVLVVFGHaq- 1004 human
XP_311092  984 PEIENFEPKHGPISGGTTIKIMGRYLNTGSr--vRAFLEQHPCEIlst--ndrEATCRTTAVpsp-mqGKLKMVFDNgv- 1057 Anopheles gambia...
BAA32308  1023 PSVLSLNPIRGPESGGTMVTITGHYLGAGSs--vAVYLGNQTCEFygr--smsEIVCVSPPSsnglgpVPVSVSVDRa-- 1096 human
Q04912     684 PVLIAVQPLFGPRAGGTCLTLEGQSLSVGTs--rAVLVNGTECLLarv--segQLLCATPPGatv-asVPLSLQVGGa-- 756  human
P51805     935 PTFDQVSPSRGPASGGTRLTISGSSLDAGSr--vTVTVRDSECQFvrr--dakAIVCISPLStlgpsqAPITLAIDRan- 1009 human
I51553     951 PSFNRVTPSRGPLSGGTWISIEGNYLNAGSd--vSVAIGGRPCMFswr--takEIRCKTPQGpst-gkAEIQILINRat- 1024 African clawed frog
BAA21571   898 PKPLSVEPQQGPQAGGTTLTIHGTHLDTGSqedvRVTLNGVPCKVtkf---gaQLQCVTGPQatr-gqMLLEVSYGGsp- 972  human
CAB57274   939 PTFYRVSPSRGPLSGGTWIGIEGSHLNAGSd--vAVSVGGRPCSFswr--nsrEIRCLTPPGqsp-gsAPIIININRaq- 1012 human
XP_309509  969 tlacstsagtrYETCSvYNYTV 990  Anopheles gambiae str. PEST
NP_002664 1239 ----------rRLQRGqFKYTL 1250 human
BAA86520  1005 ----------rTLLASpFRYTA 1016 human
XP_311092 1058 ----------rELNGDlFEYVP 1069 Anopheles gambiae str. PEST
BAA32308  1097 ----------hVDSNLqFEYID 1108 human
Q04912     757 ----------qVPGSWtFQYRE 768  human
P51805    1010 ----------iSSPGLiYTYTQ 1021 human
I51553    1025 ----------mNNSEVhYNYTE 1036 African clawed frog
BAA21571   973 ----------vPNPGIfFTYRE 984  human
CAB57274  1013 ----------lTNPEVkYNYTE 1024 human
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