Conserved Protein Domain Family
FatB

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cd01140: FatB 
Siderophore binding protein FatB. These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind their ligands in the cleft between these domains.
Statistics
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PSSM-Id: 238560
Aligned: 26 rows
Threshold Bit Score: 245.245
Created: 10-Jan-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding residues [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                          ##                   #                          #            
CAA61304     58 DSLGENKIPKNPSKVVILDLGILDTFHALRlndKVAGVPAK------NLPKYLQQFkdk---psIGGVQQVDFEAINAlK 128 Campylobacter coli
NP_607877   308 NQHPKTAKETEQQRIVATSVAVVDICDRLNl--DLVGVCDSkl---yTLPKRYDAVk------rVGLPMNPDIELIASlK 376 Streptococcus py...
CAC20626     23 AAQKPEQKTDKEPKIVATTVAITEIMDKLDl--PLVGIPSSs----kKLPKRYADVk------eTGSPMGPDLEIIRMlK 90  Listeria monocyt...
NP_561139    28 ESKESLKKENGEEIVVATSVAVTEILDELGv--KVSGVPTSs----yDLPESTKDAv------kVGNPMNPDLEIIKSlN 95  Clostridium perf...
NP_943551    44 HNLGQTVISNRPQRVAALDMNEVDFLDQLNv--PIAGMVKD------FVPHFLEKYkntpdisdLGAIVQPNMEKIYAlK 115 Listonella angui...
NP_274981    48 TARGDVQIPQNPERIAVYDLGMLDTLSKLG---VKTGLSVDk----nRLPYLEEYFktt---kpAGTLFEPDYETLNAyK 117 Neisseria mening...
ZP_00135358  31 TVRGDVTFTQTPAKLAVFDAVAIDILSHLDv--PIAGSPDVt----kTLPYLKPAVeka---vnIGTFFEPNLEALNSlK 101 Actinobacillus p...
NP_737491    94 EDNHGPKEITSTETVAATDNRAFELLDRWGv--DLVAAPVP------LVPFTVTNYkenpeiadLGTHREPDLEALAAaQ 165 Corynebacterium ...
NP_283390    41 TARGDAVVPKNPERVAVYDWAALDTLTELG---VNVGATTApvrvdyLQPAFDKAAt-------VGTLFEPDYEALHRyN 110 Neisseria mening...
NP_847506    45 DAHGKVKVPVNPKNVVALDNRTFETLADWGi--KLAAAPKD------IMPADSAYKkdek-vqnIGNHREPNLEIIAAaN 115 Bacillus anthrac...
Feature 1             # #                                                                       
CAA61304    129 PDLIIISGRQS-KFYEKLKIAPT---MFVGLDNAn--------FLSSFENNVLSVAKLYGLEKEASEKIADIKNEIEQAK 196 Campylobacter coli
NP_607877   377 PTWILSPNSLQeDLEPKYQKLDT---EYGFLNLR---------SVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQ 444 Streptococcus py...
CAC20626     91 PDMVLSTKTLEaDLKSGFEGADL---EADFLDFT---------SIASMQTEIKNLGAKFDRIEEATKLNKDLTSDIDQVK 158 Listeria monocyt...
NP_561139    96 PDVVVSVDTLGeDYKKLFTDNNI---PSEFIDLT---------TLEGLKTSISTLGERFNKTEKANEILNELKVKEDEFV 163 Clostridium perf...
NP_943551   116 PDLVLMTPLHAnQYEELSKLAPT---VHFDIDFRnsh----ghHVDIIKQHVIDLGEIFNKQTLAQKKVAEIDAKVDEVQ 188 Listonella angui...
NP_274981   118 PQLIIIGSRAAkAFDKLNEIAPT---IEMTADTAn--------LKESAKERIDALAQIFGKQAEADKLKAEIDASFEAAK 186 Neisseria mening...
ZP_00135358 102 PDLIIVATRSAaKLDDVKTISNA---IDLSIPTNl-------nTLQAGLQEIEHLGKLFNKEEKATQLKTEIEALLQETK 171 Actinobacillus p...
NP_737491   166 PDLVINGQRFAqYYDDIVSLAPGa--TVVELDPRdg-----epLDQELIRQAETLGQIFGEEEDAATLVEDFNTALERAK 238 Corynebacterium ...
NP_283390   111 PQLVITGGPGAeAYEQLAKNATT---IDLTVDNGn--------IRTSGEKQMETLARIFGKEARAAELKAQIDALFAQTR 179 Neisseria mening...
NP_847506   116 PELVIVGQRFAdHYEEIKKLVPNaavIDLNVDVSekatkpgenLVKGLKDSTITLGKIFNKDKEAKQLVADFDKSIEKAK 195 Bacillus anthrac...
Feature 1                              #                                 #                      
CAA61304    197 SIV--DEDKKALIVLTNS--NKISAFGP--QSRFGIIHDVlGINAVDENvk--vgTHGKSINSEFILeKNPDYLFVVDRN 268 Campylobacter coli
NP_607877   445 AKR--KGKKKPKVLILMGlpGSYLVATN--QSYVGNLLDLaGGENVYQSd----eKEFLSVNPEDMLaKEPDLILRTAHA 516 Streptococcus py...
CAC20626    159 SNV--AKKKKPTVLILMGvpGSYLVVTE--HAYIGDLVKLaGGENVIKDq----kVEYLASNTEYLQsANPDIILRAAHG 230 Listeria monocyt...
NP_561139   164 NLSk-EEKKNVLLVFAAP--GSMMIATP--SSYIGNLVDKvGANNIVKDd----kKPFVSYSNEEIVkLNPDMVLVMTHG 234 Clostridium perf...
NP_943551   189 ALTa-ERSEKALVVMHNN--GSFSSFGI--ESRYGFVFDVlGVKPASTEia--asLHGQPISSEFINqANPDILYIIDRT 261 Listonella angui...
NP_274981   187 TAA--QGKGKGLVILVNG--GKMSAFGPs-SRLGGWLHKDiGVPAVDESik--egSHGQPISFEYLKeKNPDWLFVLDRS 259 Neisseria mening...
ZP_00135358 172 SAV--KGKGNGLIVIVNG--GKMSAFGN--KGRLGWIHSAlDIPMAIENvgqkgtSHGQPVSFELLQkVNPDWLFVLDRT 245 Actinobacillus p...
NP_737491   239 SAYaeISDQTVMAVNVSG--GNIGYIAPsvGRTFGPIFDLvGLTPALEVanasndHEGDDINVEAIAqANPDIILVMDRD 316 Corynebacterium ...
NP_283390   180 EAA--KGKGRGLVLSVTG--NKVSAFGTq-SRLASWIHGDiGLPPVDESlr--neGHGQPVSFEYIKeKNPDWIFIIDRT 252 Neisseria mening...
NP_847506   196 SAY--NGKDKVMSVIVTG--GNIGFAAPhsGRVWGPMYEIfGWTPALEVsnstagHKGDDVSVEAIAqTNPDWLFVLDRD 271 Bacillus anthrac...
Feature 1                                                                          
CAA61304    269 IIVg-----nKERAQGILDNAL-VTKTNAATNNKIIYLDPEYWYLASGNg----lESLKTMILEVTN 325 Campylobacter coli
NP_607877   517 IPDkv----kVMFDKEFAENDI-WKHFTAVKEGKVYDLDNTLFGMSAKLnypealDTLTQLFDHVGD 578 Streptococcus pyogenes MGAS8232
CAC20626    231 MPAev----vKMFDEEFKTNDI-WKHFDAVKNNRVYDLDENLFGMTASLna---pEALKEMEKMLYD 289 Listeria monocytogenes
NP_561139   235 MPEq-----aKKMAEEKFASDPaWSRIEAVKEGKVYYLENGYFGMSANLkv---iESLDKLGEIIYG 293 Clostridium perfringens str. 13
NP_943551   262 AVMeg----kPVIDAEHLANPL-LRQTKAWKNGKVIFVDADAWYITSASi-----TSLKIVIDDIIK 318 Listonella anguillarum
NP_274981   260 AAIge----eGQAAKDVLDNPL-VAETTAWKKGQVVYLVPETYLAAGGA------QELLNASKQVAD 315 Neisseria meningitidis MC58
ZP_00135358 246 AAIge----eGKTAREVLDNAL-VHQTNAWKNNQVVYLSSSAYLAAGGV------TQMREDLTNIKK 301 Actinobacillus pleuropneumoni...
NP_737491   317 AGTetrneadFTPAEQIITNSEvMANVTAIKDGKVFIAPADTYTNENIIt----yTEILNGMADLFE 379 Corynebacterium efficiens YS-314
NP_283390   253 AAIgq----eGPAAVEVLDNAL-VRGTNAWKRKQIIVMPAANYIVAGGS------RQLIQAAEQLKE 308 Neisseria meningitidis Z2491
NP_847506   272 AATsda--akSAPAQDVISKSPaLQNTTAVSKKQVVYAPADTYTNESIQty---iELFGNLAKTLAK 333 Bacillus anthracis str. Ames

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