2OH3,2FZF,1VJX


Conserved Protein Domain Family
Ferritin_like_AB

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cd01045: Ferritin_like_AB 
Click on image for an interactive view with Cn3D
Uncharacterized family of ferritin-like proteins found in archaea and bacteria
Ferritin-like domain found in archaea and bacteria (Ferritin_like_AB). This uncharacterized domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins whose function is unknown. This family includes unknown or hypothetical proteins which were sequenced from mostly anaerobic or microaerophilic metal-metabolizing and/or nitrogen-fixing microbes. The family includes sequences from ferric-, sulfate-, and arsenic-reducing bacteria, Geobacter, Magnetospirillum, Desulfovibrio, and Desulfitobacterium. Also included are several nitrogen-fixing endosymbiotic bacteria, Rhizobium, Mesorhizobium, and Bradyrhizobium; also phototrophic purple nonsulfur bacteria, Rhodobacter and Rhodopseudomonas, as well as, obligate thermophiles, Thermotoga, Thermoanaerobacter, and Pyrococcus. The conserved residues of a diiron center are present in this uncharacterized domain.
Statistics
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PSSM-Id: 153104
View PSSM: cd01045
Aligned: 174 rows
Threshold Bit Score: 61.2101
Threshold Setting Gi: 57640997
Created: 24-Sep-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
diiron binding
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:diiron binding motif [ion binding site]
Evidence:
  • Comment:The conserved residues of a diiron center are present in the Ferritin-like AB domain.
  • Citation:PMID 8749363

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                 #                                #  #                                  
2OH3_A         8 EFLAHAIALETEAAERYVELADXXEahnnldTATVFRDXARFSTLHGDEIKQRSRal-------------eLPKLXSWQY 74  Magnetospirillu...
YP_486747     20 ALYAVALDLAERAHRHYGALAARVDenf-rpVRCVFEVLTARERERVGSLIAACEqdc-----------grVPTPRDRPW 87  Rhodopseudomona...
YP_002364023   6 EFLAYAVKLEEEAAIRFGELADVMQscgngdVGKLFRRLSDYSRLHLADAKARSGfr-------------dIPEMRPNEF 72  Methylocella si...
YP_001769720  17 SFFALAHLMESEAARSYAEFADLMRkqgrpdLADTFARIAGEESGHAAHISHWSQaaegrgpdsqdlrwppPPTFEREDA 96  Methylobacteriu...
ACF98094      17 ELLAIAYAMEQEAVAGYSELAGRMRrenrpeLAAVFDTLVGEESRHLDNVVSWSEtvs----------gkpPDLNNIRWK 86  uncultured bact...
ZP_05376818   17 EFFALARAMEADAVRHYTETANALRkqnslpLAYIFELLAKFERDHVDRVAEWAAehkga-------avatVAPWPIPDA 89  Hyphomicrobium ...
CAM76368       6 EFLVYAARLEQEAALRFDELADAAGsfenteVADFFRQMADYSRMHLEEARKRGGfh-------------dLPEIPPGEY 72  Magnetospirillu...
YP_982565      6 EFLAHTIQLESEAALRFGQLADAMTtagnkeVGRLFRRLADYSLLHLGDARARAGfr-------------tLPEMKAGDY 72  Polaromonas nap...
NP_766953     94 ELFALANAMEEEAAKRYSALAEEMRrqnkdaLAEVFANLAAAEREHVDSVARWSQsrrg---------kapDPALVRWEA 164 Bradyrhizobium ...
CAM76145       7 EFLAYAARLEQEAVLRFKELAEAAKthgnkeVHEFFAQMAHYSQMHYQQAKERCGyh-------------dLPVMSHDDF 73  Magnetospirillu...
Feature 1                                        #                             #  #        
2OH3_A        75 RWktppevgde--ndihylxtPYHALRYARDNEIRGXEYYKEAAANSAdpevKRLGADFAAEEAEHVVALDKWI 146 Magnetospirillum magn...
YP_486747     88 VApdlvpeselsdieqsslstPYTAWAIAVQHRQRAFVFWTYVIAVAMdaevRSVAEGFAREALADGNLLRRER 161 Rhodopseudomonas palu...
YP_002364023  73 AWpdfespesaaiwaadpfigRDQALEIARDAEQASLDYYTKIYQTTNdsevRVLAKEFVEEETQHVAEINKWI 146 Methylocella silvestr...
YP_001769720  97 AEiags-----------rlltPYRVLTIAVRNEERAFAFWAYVAAQTRseevRRAAEAMAREELEHVTTFRRER 159 Methylobacterium sp. ...
ACF98094      87 RAetfddegar--aiapellsAYRAFSMAVRNEERAFIFWTYVAAHAPreelRMAAERMAREELAHLATLRRER 158 uncultured bacterium ...
ZP_05376818   90 FDvspeeia------qsslmtPYRALAIAVRYEERSFTFWTYVAAQADge-vKEAAERMAREQLDHVSVLRQER 156 Hyphomicrobium denitr...
CAM76368      73 AWprlespeaaaiwaadpqmdVSMALSVALDAETNGLAFYQGVLDGTDdpeiKAMAAEFVEEEAEHVAAIKRWI 146 Magnetospirillum gryp...
YP_982565     73 RWpdvespeaaaiwaadpfigIEQALQVALDAESAGLDFYAEVLESTTdpeiRVLAKEFVEEESQHVAELQRWM 146 Polaromonas naphthale...
NP_766953    165 PEtfdaetare--ietsrlttPYRALAMAVRNEERAFAFWSYVAAYSRdleiKQAAEAMAREELGHISTLRKER 236 Bradyrhizobium japoni...
CAM76145      74 KWpemespeaaaiwgadplmgVQEAMRLALEAELRGYEFYKNVLDTTTdpeiRAMAQEFTDEEAEHVEAIQRWI 147 Magnetospirillum gryp...

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