3HRL


Conserved Protein Domain Family
Endonuclease_DUF559
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cd01038: Endonuclease_DUF559 
Putative endonuclease
Domain of unknown function 559 (DUF559) is a putative endonuclease of unknown function, belongs to a superfamily of nucleases including very short patch repair (Vsr) endonucleases, archaeal Holliday junction resolvases, MutH methyl-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and FokI.
Links
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Statistics
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PSSM-Id: 411708
Aligned: 51 rows
Threshold Bit Score: 88.414
Created: 4-Sep-2001
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Conserved Features/SitesClick to see Conserved Features Help
 
putative active
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:
  • Comment:by similarity to the very short patch endonuclease family
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1            #                                     #                #         #          
3HRL_A         4 XSEAEAKLWQHLRAgr---------lnGYKFRRQQPXGNYIVDFXCVtPKLIVEADGGQHAEqa---vYDHARTVYLNSL 71  Neisseria gonor...
WP_146432503 127 ESEAERMFVELLQLh-----------gITGWFAQLPFRGWAVDFAFPeSKLAVEINGWAFHRsrarwmRDQDKSNALTSA 195 Tsukamurella sp...
WP_124973318 181 GSGVESIVRTHLKRm------------RLRFDIQVRIGVWPVDVLIG-NWLVIEIDGFEYHSgesdfgRDRRKDRELHGM 247 Zimmermannella ...
WP_064056948 282 RSSIEIKLETAMKDa------------NIPFEPQFKLGRWICDFGIPsHNIIIECDGVYWHNlpkqkeKDARKNKDVHKK 349 Bacillus wiedma...
KKQ53753      20 MTLAEKTLWQYLRNnald------ikfRRQEPFYFGEYRYVADFYCPaKKMIIEIDGDVHDDrev-keYDEFREEIFNSQ 92  Candidatus Falk...
WP_127122239  14 QTKAEAKLWYFIRNrklggkkftrqypIVYKVEGTKRYSYIADFHCAeKKLIIELDGGIHELpdq-rrYDEARDIVLHEL 92  Chryseotalea sa...
RZA00141      15 QTPAEDILWNNLRNrklmgkkflrqhpVCVMSAFGRSRYYIPDFYCNeSKLVIEADGPVHQFkk---qYDQNRDEVLKEL 91  Sphingobacteria...
WP_138806131  15 QTPSKNLLWQALRNrnfsgkkflrqhpICVKSTFGINQYYIPDFYCAeAKLVIEADGPVHLFkk---eYDKNRDDVLREL 91  Inquilinus sp. ...
RYY32854      15 PTMAEKLIWHQLRKrhiegvkflrqfpIFTIQANHEKVFYIADFYCAkYKLVIEVDGPVHLLkr---eYDANRDIIMNDW 91  Sphingobacteria...
OGI65201      25 TTEAEKIFWETILKnkk--------laEFKFTRQKPLDNFIVDFYCAsLGLVVEIDGGIHDFqk--erDKERDNLLKQKF 94  Candidatus Nomu...

Feature 1                                   
3HRL_A        72 GFTVLRFWNHeilqqtNDVLAEILRVL 98  Neisseria gonorrhoeae FA 1090
WP_146432503 196 GWSVLNFSWHhlnedpEGVITIVAETL 222 Tsukamurella sp. HKU70
WP_124973318 248 GYTVLRFTYWdvvlrwEECERQILEFV 274 Zimmermannella sp. YIM 102482-1
WP_064056948 350 GWKILRFWENeinddiEKCIKKIINLL 376 Bacillus wiedmannii
KKQ53753      93 GYKIIRFSNEqvlssmDGVLESILKAL 119 Candidatus Falkowbacteria bacterium GW2011_GWF2_38_1205
WP_127122239  93 GYKVIRFKNEe----lEDISLVLDQIR 115 Chryseotalea sanaruensis
RZA00141      92 GLYILRFKNEeiindlEGVMSKIKARL 118 Sphingobacteriaceae bacterium
WP_138806131  92 GLTILRFENDniekdiNGVLNKIKEYL 118 Inquilinus sp. KBS0705
RYY32854      92 GFSVLRFTNAeveneiDKVVGVILDFI 118 Sphingobacteriaceae bacterium
OGI65201      95 GLRILRYRNEevlenmERVKEDLIKRI 121 Candidatus Nomurabacteria bacterium RIFCSPHIGHO2_01_FULL_40_24b

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