Conserved Protein Domain Family
TroA_b

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cd01020: TroA_b 
Metal binding protein TroA_b. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).
Statistics
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PSSM-Id: 238502
Aligned: 9 rows
Threshold Bit Score: 319
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
metal binding
Feature 1:metal binding site [ion binding site]
Evidence:
  • Comment:based on sequence similarity to PsaA from Streptococcus pneumoniae
  • Citation:PMID 9862808

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                            #                                          
NP_301356    29 RPTAVVASTDVWGSVARIIAGRHVAVTSIVtgaHTDPHTYRVNPAETAAITDAALVVYNGGGYDPWVDKVLAgrp--diK 106 Mycobacterium le...
NP_696297    45 GKIEVVASINQWGSVAEDLGGSNVEVTNIMtktNVEAHDYEPTSQDVAKFGTAKVAVVNGADYDPWATKAAQpt---kaT 121 Bifidobacterium ...
NP_601829    38 NSLKVVTSTQVWADVAEAVAPDVDIEAIITg-gDIDPHSFEPSATDMAKVSEADIIIVGGGGYDSWLYGTLEdd----dR 112 Corynebacterium ...
NP_739122    38 DGLTIVASTQVWADVAEAVVEDADIHAIVQg--DEDPHSFEPSAADMARVETADIILVGGGGYDSWLYDSLEdd----dR 111 Corynebacterium ...
NP_696166    48 GPINVVASLNQWGSLAAELGGDDVEVTSIVnstNVDAHDFEPKTSDVAKLSKAQIIVANGAGYDSWATKSMTkt----tN 123 Bifidobacterium ...
ZP_00064315  31 QKITIVASTDFYAEIAKTVVGEHGTATAIIkdaNVSPEDYEPTTTVAKKVSGADIVLANGLGYDAWLNKLAKts---knT 107 Leuconostoc mese...
ZP_00069374  43 SKIKVVASVDFYGEAAKAVLGNKGTVTSVIknpSIDPHDYQPTSNVAKKVSEANFVLYNGIGYDTWMTKLAKns---kdV 119 Oenococcus oeni MCW
ZP_00027742  81 ARIPVVAAENFYGDVVQQLGGDRVDVTSILsnpDQDPHLFEASPKTARALQHASLVVYNGADYDPWMAKLLAaskgtkrV 160 Burkholderia fun...
NP_786338    31 HKVNIVATTNFYGSVAKAVGGKHVSVTSIInkpSVDPHDFEPTPTVAKTVGQADLVIANGIGYDGWMNKVVHst---qrA 107 Lactobacillus pl...
Feature 1                                                 #                                     
NP_301356   107 SVDAYSLlasrg---------------------attegPADEHVFYDLNIAKSVASLIADQLVTIDPdnaadYQANATEF 165 Mycobacterium le...
NP_696297   122 LVTAAETagi--------------------------keGDNPHVWFSAKVRSNTADAITAAYQKADPshkddYAKLNKEW 175 Bifidobacterium ...
NP_601829   113 IIHALDLsehdhsehddheheaeeahehdhdeeghdhdVDNEHVWYSTEYVSEVAEEFAEKVTELDPe----AQADATAV 188 Corynebacterium ...
NP_739122   112 IISAMDLephdhsdhdh------------dhdhdhdhdSDNEHIWYSPEAVTHVAEDLAGKVTETSPd----TRVSPDAV 175 Corynebacterium ...
NP_696166   124 IVSAASVmga--------------------------veGDNPHLWFSKDARSSMATAITDAYIKALPskkkaFQKRLKAW 177 Bifidobacterium ...
ZP_00064315 108 KLIRVGEdvln------------------------kktGVNPHLWNDPETMSKTANYLATELGKKDPknrdyYKKNAKKY 163 Leuconostoc mese...
ZP_00069374 120 VSIRVGEdllg------------------------kkdGDNPHLWYQSKTMPKLANYLAKRFGEVQPknkkyFQKNAKKF 175 Oenococcus oeni MCW
ZP_00027742 161 TIVAADLtgk--------------------------ksGDNPHLWYDPATMPKVARAVSEALVAADPahksaYDANLAKF 214 Burkholderia fun...
NP_786338   108 KLIRVGEdvmh------------------------rkeGANEHLWYDSATMPATANYLANQLAKKQPqyrtyFKANARKY 163 Lactobacillus pl...
Feature 1                                    #                                                  
NP_301356   166 CRSADAIAISEHAIAsdy---paAGVIVTEPVVHYLLQASGLVNRTPPAFTAThenenDPSAADMAAALNLINHRqvsAL 242 Mycobacterium le...
NP_696297   176 HAKEDQLESKIKETSakt---egLPYAATESVAWYLADDLKMTDATPKGYAQAsanesEPTPADIKDFQDTLKAGfikMF 252 Bifidobacterium ...
NP_601829   189 TTKMDELHNQIHDLPa-------VRIAQTEPIADHILSHSDMVESTPEGYRATtlsesEPTAADVASFQDAINNGdldVL 261 Corynebacterium ...
NP_739122   176 VTQMADLAARIADLPa-------ARVAQTEPIADHLLAHSAMIESTPAGYRATtlsegEPTAADVAAFHEAIRNGeidIL 248 Corynebacterium ...
NP_696166   178 QADEKSLETWASEFTksh---snLTYAATEPVVYYLMADLGFKDQTPKGYTQStasggEPAPADLQSFQKLIEDKg-vDV 253 Bifidobacterium ...
ZP_00064315 164 VASLKPVNDLITKISkka---dgQTVAQTEPVFEYMLDALGYKIMDTDFSEAIee-gnDPSPATLAALKSAITNHk-iAF 238 Leuconostoc mese...
ZP_00069374 176 VKSLKPIQSKIKQLSkns---kgKLVDVSEPVFDYTLKELGYKEHNTHFAKSVed-stDPSPKDIKAMQNDVKNRkiaFF 251 Oenococcus oeni MCW
ZP_00027742 215 LDSLKPVDAKVAELHgry---agVPVTATEPVFGYMSDAVGLTMRNLRFQLATmn-dtEASAADIAAFDGDLRERrvrVL 290 Burkholderia fun...
NP_786338   164 IATLKPIQQEQAKLRakanklknRQVLVSEPVFDYALTSLGFKVANQDFENAIek-gtDPAPQVIHKMQQALKSRq-vAF 241 Lactobacillus pl...
Feature 1                                 #                             
NP_301356   243 LVNPQk-SNAATNGLQAAARrSGVPVTEVTEMLPnd-tdYLTWQRNTIDQLLTALQ 296 Mycobacterium leprae
NP_696297   253 VFNSQe-ANSTTDQITGAAKdANVPIVELAEQMPkqytnLLDWMSALVDQFAAAVK 307 Bifidobacterium longum NCC2705
NP_601829   262 IYNPQs-ASTVATSLKDLAEeKGIPVVEIYETPQnt-enFLDAFTKAVDDLTAATN 315 Corynebacterium glutamicum ATCC 13032
NP_739122   249 IHNPQs-AASVSTGIRELAEqEGIPVVEIAETPEpg-tnFLEAFKKAVADLEQAGQ 302 Corynebacterium efficiens YS-314
NP_696166   254 LVNNTqeASDATNMITGAAGrADVPVVDVSEQMPkdadtLNAWINQLINTIIDAVD 309 Bifidobacterium longum NCC2705
ZP_00064315 239 FVNNTqtSSSTVSNLIDLAKkNDIPVVNVTETIPng-enYVSWKLKELKAIEKVTQ 293 Leuconostoc mesenteroides subsp. mesente...
ZP_00069374 252 VENTQa-TDKIVGNIVKIAKaHNVPVLKVTETMPkg-ktYKEWMMDQLNQLEKIQK 305 Oenococcus oeni MCW
ZP_00027742 291 IYNSQa-TEALTKRMLKLAQqSRVPTMSVTETEPag-ktYQTWMLSQLDALGKALA 344 Burkholderia fungorum
NP_786338   242 FVNNSqvSDKLVTNMVSLAKkNQVPVLNVTETMPak-ltYQQWMLAQYRQLNQLLS 296 Lactobacillus plantarum WCFS1

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