Conserved Protein Domain Family
PG-PI_TP

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cd00917: PG-PI_TP 
The phosphatidylinositol/phosphatidylglycerol transfer protein (PG/PI-TP) has been shown to bind phosphatidylglycerol and phosphatidylinositol, but the biological significance of this is still obscure. These proteins belong to the ML domain family.
Statistics
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PSSM-Id: 238459
Aligned: 20 rows
Threshold Bit Score: 112.419
Created: 5-Feb-2003
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative lipid
Feature 1:putative lipid binding cavity [chemical binding site]
Evidence:
  • Comment:hydrophobic cavity of conserved residues

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1     #                #  # #      #     # # #             # # #             #        
AAD16095   47 LEYCNdpsg----dilDIkQVDLSPn--pPLPGKTLAITASGTLREKIEDgaYVLLEVKYGLITLVRqtADLCEqlvn-- 118 Aspergillus oryzae
NP_189996  27 FTYCDkrl-----dpvKVtGVKISPd--pVVSGAAATFKIFGSTGEDISGg-KVVIRVLYVGIPVHTetHDLCDet---- 94  thale cress
NP_594778  50 ASYCAdwdrg--ddhvVVdYINLIPn--pPAAGKNLTIETEINVGTTVLNgsYVDIQVKYGFVRIVNerLDICDkayel- 124 fission yeast
NP_180205  29 FENCKnapidynygitNVtRVEISPypvgPYDEPTITISGFTSDDSYIIYraTIHVLYKYENVNSTIinYDLSDvmg--- 105 thale cress
NP_196266  27 VHYCEenae----yevKVkEVDISPn--pIAPGEPATFTISANTGREISFg-KLVIEVSYFGWHVHSetHDLCTet---- 95  thale cress
AAF69155   27 FKYCNgig-----yvdKItKVEISP----DDPSTVITISGLTRRGLVYAG--TVVVASGIGEFNIPFkyYDFCQlc---- 91  thale cress
AAK32852   27 FQTCDtgke----yplKVsSVEISPd--pVKRSGNGEITITGVTNKEISDgvTVNLKLAVGMFPVSTksYSLCDit---- 96  thale cress
NP_911279  27 VEYCNkgkk----ypvKVsGVEIVPd--pVARGEPATFKISASTDKTIGKg-KLVIDVKYFFFYVHSetRELCDvt---- 95  Japanese rice
CAE02713   50 FLVCDrpep----qaiNItALDASAy--pLPAGQDVEFEVVGKVNHLVQDgaYLNVSVYSGFREVHRgiHPLCDlmkqhk 123 Yarrowia lipolytica
XP_402348  65 WSSCGtgd-----evvNVeSIVVSPd--pPVPGQNLTVRAKGTVKDEVSDgtFADVIVKLGLIRLLArrFDVCEqaresn 137 Ustilago maydis 521
Feature 1           #      #                   # # # #           #  # # #
AAD16095  119 velkCPLgPGDMTLTkqvdlp-----kqippgKYTVQADVFns----dGEHITCLKALN 168 Aspergillus oryzae
NP_189996  95 ---aCPVaPGSFVLShsqtlp-----sitppgTYTLKMTINdk----nGGRLTCISFKF 141 thale cress
NP_594778 125 aaveCPVePGIITKQatislp-----waippgRYHVLATAYna----dGEQLTCVSASV 174 fission yeast
NP_180205 106 -edpCSIePGEKFVLtlskvpglqslphkdksKIVISLVDEygddaevPLLKMCVEFDN 163 thale cress
NP_196266  96 ---sCPIqTGDFLVAhsqvlp-----gytppgSYLLKMKMLda----kKKELTCIKFSF 142 thale cress
AAF69155   92 ---kCPMlSGTNFVFtlsqili---pkafasdKLAVTLSLIsr----dQTEGVCVYFDF 140 thale cress
AAK32852   97 ---aCPVaPGPIVLTlpniftp---rekrtaiGYTIIISITdk---plKESMMCILFVV 146 thale cress
NP_911279  96 ---sCPA-SGDFLVAhqqtlp-----sytppgSYTITMKMLgd----nDEELSCISFGF 141 Japanese rice
CAE02713  124 igrgCPLkPTKKDIRfkrtvsi---pdwipssRYFVLATIYn------PDKSTVISFSG 173 Yarrowia lipolytica
XP_402348 138 adlqCPLsAGEYELEhtvalp-----reippgKFNVHITGEnq----dGSNLLCLDLSI 187 Ustilago maydis 521

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