1EO1,1P90,1O13


Conserved Protein Domain Family
NifX_NifB

?
cd00562: NifX_NifB 
Click on image for an interactive view with Cn3D
This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).
Statistics
?
PSSM-Id: 238315
Aligned: 111 rows
Threshold Bit Score: 58.7972
Created: 7-Mar-2002
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1EO1_A        2 KIAIASsgtdlg-sevsrFFGRAPYFMIVEMkkgniessEVIENpsasas---ggagirTAQIIAN---------NGVKA 68  Methanothermobac...
AAB85661    298 VVAVPLadnhgmesristHFGRADSFLIARTrrgeildyRIIENsgkslr---tkrgirAAELLKD---------ENIDV 365 Methanothermobac...
NP_617005   295 KIAVPVlmqeglhskvsrHFSKAPYFIFIELenndiiswDVSENpaagle---kkkglkAAEFLKD---------QGVNV 362 Methanosarcina a...
AAB90572      2 RVAMPIldqkdg-lrvapHFGKARRFYILDLesgkssvvEIPEAekgr--------grmIAEILRE---------KGVSV 63  Archaeoglobus fu...
AAB85666      2 KICIPVmeergmdskvseHFGKTPLFAFYDDevneleiiKIEGRhtgg--------rltPAEIVVN---------SDADL 64  Methanothermobac...
ZP_00147682  53 KVAIPImipeglqsklsrHIGKAPYYIFIELkdnkimswDIGENpaadld---rkrgvkTAEYLEE---------QDVNI 120 Methanococcoides...
CAG21428      2 CIAIAItlrs----qvagHFGKAAAFMVYDSqgqfieriENTGSkelgc-----khkkvIQRQLSE---------LGVKE 63  Photobacterium p...
ZP_00296752 294 RLALPVldnngfqaklseHLGKAPYFLFVEIeegkvgdnQIVENrffnse---kkggmkAADLIIR---------EKANV 361 Methanosarcina b...
NP_987566     2 KIAVPVfenk-----iceHFGKTALFLIFELde----tcEVVNIlrvqntpcdgngggsPAEKLLL---------ENPDV 63  Methanococcus ma...
ZP_00055148   2 KIAVAVdssya---kvsgHAGRARHWLVYETdr----asSSVRVel------------eAAQVFHHyegdgphplDGIET 62  Magnetospirillum...
1EO1_A       69 VIASSpGPNAFEVLNElGIKIYRAtg---tsVEENLKLFT 105 Methanothermobacter thermautotrophicus
AAB85661    366 LVIEKlSEGPELLFSDyLLGKVPPeg---ssLEEVIKNAS 402 Methanothermobacter thermautotrophicus str. Delta H
NP_617005   363 LIAGEiGEAPFHTLRDnFVKLLQMpee-iedVEQVVKKVS 401 Methanosarcina acetivorans C2A
AAB90572     64 VVCRNiGEGALERLKEaGIEVRKTdk---snPDDAVEDLR 100 Archaeoglobus fulgidus DSM 4304
AAB85666     65 LICTNmGSKAINLLRThGVDVLMGar---gtVAETLNLLK 101 Methanothermobacter thermautotrophicus str. Delta H
ZP_00147682 121 VIVKDiGGGPFHKFHDsFIKLLEMpd----dVEDVETLIG 156 Methanococcoides burtonii DSM 6242
CAG21428     64 IVLGNvGQRSLGRLLNaGFSVTKVpq---rsSIDAVMTGK 100 Photobacterium profundum
ZP_00296752 362 LAVRNvGEGPYYMLRDnFIKILQIpdg-vdtAREVLDRFQ 400 Methanosarcina barkeri str. fusaro
NP_987566    64 IIYNTmGKKRIETLKGrVNLYHTKtqdiksaLKECIDNIL 103 Methanococcus maripaludis S2
ZP_00055148  63 VIAISaGEGFMRRMQArGIDARQTae---tnPDKAVADYL 99  Magnetospirillum magnetotacticum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap