1RTU,1RDS,1CH0,4GSP,1FUT,2SAR,1AY7,1GOY,1BRS,1JBS,1DE3


Conserved Protein Domain Family
microbial_RNases
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cd00389: microbial_RNases 
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microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th, Pb, N1, and Ms) and bacterial RNases (barnase, binase, RNase Sa) , the majority of which are guanyl specific and fungal ribotoxins.
Links
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Statistics
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PSSM-Id: 238228
Aligned: 25 rows
Threshold Bit Score: 56.0876
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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active site
Conserved site includes 4 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Structure:1RTU:Ustilago sphaerogena ribonuclease U2
  • Citation:PMID 7492561
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                          #                            
1RTU         19 INTAIQGAlddvan---------------------------gdrpdnYPHQYYXeasedit------------------- 52  Ustilago sphaero...
1RDS         17 VSAAKAKGyslyes---------------------------gdtiddYPHEYHDyegfd--------------------- 48  Aspergillus phoe...
1CH0_A       16 VSTAQAAGyklhedg-------------------------etvgsnsYPHEFRNwqgfd--------------------- 49  Aspergillus oryzae
4GSP         16 VSTAQAAGyklhedg-------------------------etvgsnsYPHKYNNyegfd--------------------- 49  Aspergillus oryzae
1FUT         16 VRAAANAAcqyyqnd-------------------------dtagsstYPHTYNNyegfd--------------------- 49  Gibberella fujik...
P81762       19 VTNAIRSAragg--------------------------------sgnYPHVYNNfegfs--------------------- 45  oyster mushroom
P07736       18 VNRAINNAksgqy------------------------------sstgYPHTYNNyegfdf-------------------- 47  Ustilago sphaero...
P09646       16 ISAALNKGysyyedg-------------------------atagsssYPHRYNNyegfd--------------------- 49  Neurospora crassa
1JBS_A       29 AESNSHHAplsdg-----------------------------ktgssYPHWFTNgydgngklikgrtpikfgkadcdrpp 79  Aspergillus rest...
ZP_00081341  69 AAMLQSLNgsnnrnlppkfvtkaqakkmgwrpgrdlwastrlkgksiGGDRFANregrl--------------------- 127 Geobacter metall...

Feature 1                      #                        #               # 
1RTU         53 ------lccgsgPWSEFPLVYngpyys--srdnyvSPGPDRVIYQTntgEFCATVTHT 102 Ustilago sphaerogena
1RDS         49 -------fpvsgTYYEYPIMSdydv------ytggSPGADRVIFNGd-dELAGVITHT 92  Aspergillus phoenicis
1CH0_A       50 -------fsvssPYYEWPILSsgdv------ysggSPGADRVVFNEn-nQLAGVITHT 93  Aspergillus oryzae
4GSP         50 -------fsvssPYYEWPILSsgdv------ysggSPGADRVVFNEn-nQLAGVITHT 93  Aspergillus oryzae
1FUT         50 -------fpvdgPYQEFPIKSggvy-------tggSPGADRVVINTn-cEYAGAITHT 92  Gibberella fujikuroi
P81762       46 -------fsctpTFFEFPVFRgsvy-------sggSPGADRVIYDQs-gRFCACLTHT 88  oyster mushroom
P07736       48 ------sdycdgPYKEYPLKTsssg------ytggSPGADRVVYDSndgTFCGAITHT 93  Ustilago sphaerogena
P09646       50 -------fptakPWYEFPILSsgrv------ytggSPGADRVIFDSh-gNLDMLITHN 93  Neurospora crassa
1JBS_A       80 khsqngmgkddhYLLEFPTFPdghdykfdskkpkeDPGPARVIYTYpnkVFCGIVAHQ 137 Aspergillus restrictus
ZP_00081341 128 -------paggkKWHEADLDYqg-----------gHRGAKRLIYSNd-gLRMVTVDHY 166 Geobacter metallireducens

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