1IOO,1BK7,1IQQ,1JY5,1BOL,1DIX


Conserved Protein Domain Family
RNase_T2
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cd00374: RNase_T2 
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Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf senescence in order to scavenge phosphate from ribonucleotides. They are also expressed in response to wounding or pathogen invasion. S-RNases are thought to prevent self-fertilization by acting as selective cytotoxins of "self" pollen.
Links
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Statistics
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PSSM-Id: 238220
Aligned: 96 rows
Threshold Bit Score: 104.846
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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active siteCAS motifs
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                   #  #                                
1IOO_A        2 FEYLQLVLTWPASFCyanhce--------------riapnnFTIHGLWPDnvk-----------trLHNCkpkptys--- 53  Persian tobacco
NP_900626    30 FAHYTFALAWQPGFCtaggegcl----------psqpkeelIGLHGLWPSepksledkgvkvqqwwASGCsmlphv---- 95  Chromobacterium ...
NP_900630    31 FSYYTLTLAWQPGFCklsqacqa-----------pqnpaaaIALLGLWPSlpvslqeqgvkdqdwrSKGClyfshs---- 95  Chromobacterium ...
P21338       34 FDRYVLALSWQTGFCqsqhdrnrnerdecrlqtettnkadfLTVHGLWPGlpksvaargvderrwmRFGCatrpipnlpe 113 Escherichia coli
CAG69845     56 LQGYVMQIEMTPATCsldaskrkq---------rkclegysLTVMGLIPEt--------------sSQDCkttt------ 106 Acinetobacter sp...
NP_720115   167 YDSHVLALSWQSTFCelygsrkaecra--lrqttdapqwqhFSLHGLWPNrqqc---------gtrYGFCssvkqqpsd- 234 Shewanella oneid...
NP_386308    41 RTEYVLAVSWQPGFCetwpdrkecig-----qtaerfdatnFSLHGLWPLk---------------KSYCgveadlkard 100 Sinorhizobium me...
NP_103159    91 KPEYVFALSWQPAFCetkssktecra-----qnpsefdatnFTLHGLWPQpn-------------gNFYCqvaasdkand 152 Mesorhizobium lo...
ZP_00268504 135 TSAFVLALSWQPAFCegrptkpecas-----qtadrldadhFALHGLWPQpr-------------gRAYCgvdaaavald 196 Rhodospirillum r...
ZP_00328395 144 ARKYVLAISWQPSFCqtrqyipecis-----qttdrydannFTLHGLWPDk---------------LTYCgvsnqdinnd 203 Trichodesmium er...

Feature 1                                               ##  ##                                  
1IOO_A       54 --------yftgkmLNDLDKHWMQLkfeqdygrteqpSWKYQYIKHGSCCqk--ryNQNTYFGlALRLKDk-FDLLRTLQ 122 Persian tobacco
NP_900626    96 --------tavpllSEELRQRLKETmpql-----asdLQTHEYVKHVQCFg----yDANEFFS-TALQMReaVVDSDFGR 157 Chromobacterium ...
NP_900630    96 --------vddpqlSDEVRVNLLKVmprl----idddLISSEFIKHAQCFg----fQGDEYFS-KALKLRhfVVSSPFGA 158 Chromobacterium ...
P21338      114 arasrmcsspetglSLETAAKLSEVmpgag---grscLERYEYAKHGACFg----fDPDAYFG-TMVRLNqeIKESEAGK 185 Escherichia coli
CAG69845    107 ----------saslSPIQTSVVARLmpd-------enNRTQLWRNVGGCMp----mNASQYFR-TIVNFAdrLKIPAELT 164 Acinetobacter sp...
NP_720115   235 -----fcdypevplNASVQKNLEEVmpsar---ygtcLERHEWWKHGTCRd----qDPNDYFL-LATQLTqeVNASVWVK 301 Shewanella oneid...
NP_386308   101 rk-gdwlelpevdmGDETAKRLLVAmpgv-----ksgLDRHQWLRNGTCQt----aNAEDYFA-LQLRLLdeLNRSAVRA 169 Sinorhizobium me...
NP_103159   153 np-ahwkdlppvnlDAGTRKELDQVmpgt-----asqLERHEWIKHGTCYg----kSQQEYFS-DALGLMrqVNASPVRD 221 Mesorhizobium lo...
ZP_00268504 197 ke-gawdrlpavalSEPTRRALVRAmpgt-----asfLDRHEWIKHGTCAdagagpGAEAYYA-ASLALLeaINASPVRA 269 Rhodospirillum r...
ZP_00328395 204 kq-rewddlprlnlDQETTSELAIVmpgv-----qsyLHRHEWTKHGTCDg----rDEDTYYD-VSIDLLneVNASEVQD 272 Trichodesmium er...

Feature 1                                                                                       
1IOO_A      123 Thriip------gssytFQDIFDAIKtvsqenPDIKCAevtk-gtpELYEIGICFtpn---------adsMFRCPqs--- 183 Persian tobacco
NP_900626   158 Yllaqagqt-rsdaevkDAFAKGYATger-gaLQLRCAkdgk-grnVLTELWFTLkk-----------dkLDSFPeadsf 223 Chromobacterium ...
NP_900630   159 Ylegkkgqv-vdqeavrQAFIHAFGAasssalSLRCQRdaq--qhsLLTSLEIRIsa-----------qkISAFPaeasl 224 Chromobacterium ...
P21338      186 Fladnygkt-vsrrdfdAAFAKSWGKenv-kaVKLTCQgn----paYLTEIQISIka-----------daINAPLsansf 248 Escherichia coli
CAG69845    165 Gpiskdv----qkstirQQFMRLNPNlpa-ngIRFSCQsvr--tkpMLTEVQVCYqvn----------gnYTQCAshv-- 225 Acinetobacter sp...
NP_720115   302 EfihqrigkkvtqkelnQSFDTSFGQgah-tkVTLDCAk------gLLNEIRINLpqeikls--dsipslLAKAPkak-- 370 Shewanella oneid...
NP_386308   170 Lfadaigke-ldekqikQAFDQGFGAgag-drVRMRCQsvn--grdVITGLTIGLsgdlsgk--aeladlIQAAGpt--- 240 Sinorhizobium me...
NP_103159   222 Lfaktiggk-ltadqirGAFDTAFGAgag-drVRVSCVidpsngrrLIGELTLGLagpigpn-aslkdllLASVPtn--- 295 Mesorhizobium lo...
ZP_00268504 270 Lvagriggr-letadlrQAFDAAFGAgag-qrVSVSCVrdg--grsLIGEIKLALagplgpevagvlaarIAAVPpv--- 342 Rhodospirillum r...
ZP_00328395 273 Lftenigkr-itqsqieTAFDNSFGKgag-qsVKIKCNg------gLISELQIKMrrplv-----geklrDVLIPts--- 336 Trichodesmium er...

Feature 1                           
1IOO_A      184 ---------dTCdktaKVLF 194 Persian tobacco
NP_900626   224 ldtpvaeredTCs--qPFVL 241 Chromobacterium violaceum ATCC 12472
NP_900630   225 wgavkidvadSCd--gQIWI 242 Chromobacterium violaceum ATCC 12472
P21338      249 l---pqphpgNCg--kTFVI 263 Escherichia coli
CAG69845    226 --------vsSCp--dEFTI 235 Acinetobacter sp. ADP1
NP_720115   371 --------ktNCpdplLIDM 382 Shewanella oneidensis MR-1
NP_386308   241 --------efKCak-gIADA 251 Sinorhizobium meliloti 1021
NP_103159   296 --------kaGCpi-gTVDA 306 Mesorhizobium loti MAFF303099
ZP_00268504 343 --------dpGCpg-gIVDA 353 Rhodospirillum rubrum
ZP_00328395 337 --------gsSCss-gIVDP 347 Trichodesmium erythraeum IMS101

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