1FHF,1APX,1C8I,1ITK,1ITK,1UB2,1UB2


Conserved Protein Domain Family
plant_peroxidase_like

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cd00314: plant_peroxidase_like 
Click on image for an interactive view with Cn3D
Heme-dependent peroxidases similar to plant peroxidases
Along with animal peroxidases, these enzymes belong to a group of peroxidases containing a heme prosthetic group (ferriprotoporphyrin IX), which catalyzes a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. The plant peroxidase-like superfamily is found in all three kingdoms of life and carries out a variety of biosynthetic and degradative functions. Several sub-families can be identified. Class I includes intracellular peroxidases present in fungi, plants, archaea and bacteria, called catalase-peroxidases, that can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. Catalase-peroxidases are typically comprised of two homologous domains that probably arose via a single gene duplication event. Class II includes ligninase and other extracellular fungal peroxidases, while class III is comprised of classic extracellular plant peroxidases, like horseradish peroxidase.
Statistics
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PSSM-Id: 173823
View PSSM: cd00314
Aligned: 34 rows
Threshold Bit Score: 76.8085
Threshold Setting Gi: 125548313
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
heme binding
Conserved site includes 23 residues -Click on image for an interactive view with Cn3D
Feature 1:heme binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                             ## ##  #                                                
1FHF_A     16 PIVFGVIFDAsft------dprIGASLMRLHFHDCFVqg-----------------------cDGSVLLnntdtieseqD 66  soybean
1C8I_A     27 FDVLDDLQTNfyqgs---kcesPVRKILRIVFHDAIGfspaltaa----------gqfggggaDGSIIAhsn----ielA 89  'Arthromyces ramosus'
Q539E5     27 QRAKTDLLGLiesvkr-gddlpMIAGTVRLAFHDCIGkg----------------------kcDGCIDH----------S 73  Hydra viridis
P84752     12 EAVKAALVSHgag-------vaVVGRKINLAGGPSYTvel--------------------grfDGLVSRaly----glsK 60  Aloe vera
EAY94135  123 DDFREMVSEN------------DLLLLSKEKFEEGVTpsayafalveqr--ggretislrtfvAGEIKNln-------vA 181 Indian rice
EAZ38740   39 HVIKAIIQDRg-----------IGGSLIRLIFHDCFVrlidnfarknftveelvvlsgahsvgDGHCSSfta-----rlA 102 Japanese rice
ACI64585  333 ESIPDSIERSh-----------FLGGIVRLAAHDFMDfdrtsd---------------nsfgsDGCFES----------D 376 Thalassiosira pseu...
ACO10612   34 GLINSTLEDGvr---------vLVPSIVRLVFHDCVDg------------------------cDACFNA----------D 70  Caligus rogercresseyi
ACO11521   29 YRIRAFIASQttsvp--ephlkLIPGLVRLVFHDCSGkn-----------------------cDGCINK----------T 73  Caligus rogercresseyi
CBI28196  194 SSFEYRLYNFtakgnadptinqAFLAQLRALCPDVGGdvskkg---------------vpldkDSQFKFdvsf---fknV 255 wine grape
Feature 1                                                                                     
1FHF_A     67 ALPNins---------irGLDVVNDIKTAvens----cpdtVSCADI-LAIAAEIASVlg---------------ggPGW 117 soybean
1C8I_A     90 FPANggl---------tdTIEALRAVGINh----------gVSFGDL-IQFATAVGMSncp--------------gsPRL 135 'Arthromyces ramosus'
Q539E5     74 KPGNagl---------krVTDRLDALYDAsyk-------gkISRADF-YALASVTALTrstanl--------sdkynGLR 128 Hydra viridis
P84752     61 LPELgth--------gltLICISWALRVM------------SNVHDFfVHVAAKVESIh-----------------qYIE 103 Aloe vera
EAY94135  182 KPVSc------------sRLQRIASIFSTtesfl--wilkiCSLSTImREFSGMHSVAslpfk----------dlilSAS 237 Indian rice
EAZ38740  103 APPDqi----------tpSYRNLLNYRCSrgggadpavvnnARDEDL-ATVARFMPAFvgklr----------pvsaLDN 161 Japanese rice
ACI64585  377 MIPNaglpsi---wcegcLLTLLYEDKYRh-----------LSRADFwIASANAVIRQtsin-----------naldLKG 431 Thalassiosira pseu...
ACO10612   71 LIANrgl---------mkPVNALEPLYQNfk--------dsLSRADF-WALASKIAIQlgvyinnrrckekscympkIDV 132 Caligus rogercresseyi
ACO11521   74 HPFNgrv---------fpVVEALEPLYNYkdisgf-siknvMSRADF-WAFGSIEATKlaiqlnnqrckfkgcktpiMYL 142 Caligus rogercresseyi
CBI28196  256 RDGNgvlesdqrlfgdseTQRIVKNYAGNgkgll--glrfyFEFPKAmIKMSSIGSASyl---------------ylVPT 318 wine grape
Feature 1                                      ###                            #               
1FHF_A    118 PVPLGRRDSltanrt------------lanqnlPAPFFn------------------LTQLKASFA----VQGl---NTL 160 soybean
1C8I_A    136 EFLTGRSNSsqpsp---------------psliPGPGNt------------------VTAILDRMG----DAGf---SPD 175 'Arthromyces ramosus'
Q539E5    129 KFKVGRKDCs-----------------------TSPVEsidssdi------prgsdgTSKTLQFFKs---EFGm---KTQ 173 Hydra viridis
P84752    104 SMRYGSLSPtifdnyskdcmiahgaahflkxrpPDPAEtrggavadngsgavarmptLEEYGTNLTkl-aEEG----KAN 178 Aloe vera
EAY94135  238 EKNSGGNDQnra------------------wnvPEPLMdylktnln---dsqldavnAGLSRRSFVliqgPPGt--gKTQ 294 Indian rice
EAZ38740  162 TYYRNNLDKvams-----------------lisISTASlqynf----------ygssCPNAEQTISn--vVYGlidaDPS 212 Japanese rice
ACI64585  432 VFAWGRVDAescsg--------------ssnrlPAPTG-------------------CAQTEAAFIt---RMGl---EWI 472 Thalassiosira pseu...
ACO10612  133 RFRFGRKDCasspvh------------sndtfiPSPFSn------------------SSSLFPWFKe---NFNf---KPN 176 Caligus rogercresseyi
ACO11521  143 PFKFGRKDCp-----------------------TSPYYttditpe-----lppafldNRATLRFFRk---NFGf---NAE 188 Caligus rogercresseyi
CBI28196  319 ERRDGRLVS------------------------LSPDAlnlla----------ltdsIHVLRQKFA----AKGl---NNH 357 wine grape
Feature 1         ##   ## #        #####                                                      
1FHF_A    161 DLVTLS--GGHTF--------GRARCstfinrlynfsntgnpdptlntty----------levlrarcpqnatgdnltnl 220 soybean
1C8I_A    176 EVVDLL--AAHSL--------ASQEGlnsaifr---------------------------------------------sp 200 'Arthromyces ramosus'
Q539E5    174 EAVALL--GAHTLgrcslqnsGFVGSwvdqrfsta----------------------------------------ppgee 211 Hydra viridis
P84752    179 FDAAMVklKNFSFilmf-gvlGTIISfclissgavlllkhhvfpdsninpss-------gaaitsgvrgdlrayvvayld 250 Aloe vera
EAY94135  295 TILGLLsaVLHSAparmqtkgGFDVKkhgpeldiegnfrqrlygqlnsdgkpdftlnpayaaelrercpssggdqnlfal 374 Indian rice
EAZ38740  213 MAPALLrlHFHDCfv-----mGFNASilldppkak-----------------------------------------gspe 246 Japanese rice
ACI64585  473 DAVALM--GAHSL--------GRGSIdfsghegv-------------------------------------------wva 499 Thalassiosira pseu...
ACO10612  177 QVVAIM--GMHTL--------GKAGSp----------------------------------------------------- 193 Caligus rogercresseyi
ACO11521  189 ETTAIM--GGHSI--------GFTANatripg----------------------------------------------tw 212 Caligus rogercresseyi
CBI28196  358 DLVTLV--GAHTI--------GQTDCsffqyrlynfmekgnadptin----------------qaflaqlhalcpecgnv 411 wine grape
Feature 1                                                                    # #              
1FHF_A    221 dlstPDQFDN--------RYYSNLLQln---------------------------------gLLQSDQELFSTpg----- 254 soybean
1C8I_A    201 ldstPQVFDT--------QFYIETLLkgttqpgpslgf-------------aeelspfpgefRMRSDALLARDs------ 253 'Arthromyces ramosus'
Q539E5    212 nlspTSILDN--------AYYRMIIDivpwtqvningtriqwqepsnsipndklpeskrsplLLNSDMAISWIikpsdal 283 Hydra viridis
P84752    251 psrtSFTVDN--------AIYGEIRRtvl-------------------------------awLIDSGTLQLSE------- 284 Aloe vera
EAY94135  375 dpasQFRFDN--------QYYRNILAmn---------------------------------gLLSSDEVLLTKs------ 407 Indian rice
EAZ38740  247 ktgiPFRGYNp------lNKFKAAFKafc-------------------------------pgKVPCPEILAFA------- 282 Japanese rice
ACI64585  500 nadeAQIFDK--------RYYEEIYSnswrprvgertqnw--------ttgppnsddpnprlMLNTDICLVYDidesvdc 563 Thalassiosira pseu...
ACO10612  194 ---fNDTWENgstdgisnFYFRKIADpnhcwvqeyvtpersg----lphkaffwrtdefkgfALPVDMTLFKAiqvnett 266 Caligus rogercresseyi
ACO11521  213 evgnVDGFSN--------QYFKNIINknlnwnqattltdt--------gekrfrwigngdafGLQTDINLVRDitvnttt 276 Caligus rogercresseyi
CBI28196  412 strvPLDKDSqik--fdvSFFKNVRVgn---------------------------------gVLESNQRIFGDs------ 450 wine grape
Feature 1                                               #   #     
1FHF_A    255 ----------------aDTIPIVNSFSsn------qNTFFSNFRVSMIKMGN 284 soybean
1C8I_A    254 -----------------RTACRWQSMTss------nEVMGQRYRAAMAKMSV 282 'Arthromyces ramosus'
Q539E5    284 gtvscrptslktpcrhsNAHTFAKIYAkn------nALWVKDFTKAFNKMIE 329 Hydra viridis
P84752    285 -----------------KVLALVLTMV---------AATVLGVAKSMIKMGQ 310 Aloe vera
EAY94135  408 ----------------rETMELVHRYAas------nELFFAQFAKSMVKMGS 437 Indian rice
EAZ38740  283 -----------------ARNSVANSGGlvyp--vppGTRKGNFSSAFSVFSR 315 Japanese rice
ACI64585  564 ct------rtdqffpegGTECLTDELAsrqcpfysqSSSRIEAVDAVEEMLG 609 Thalassiosira pseudonana CCMP1335
ACO10612  267 ges----sctyhdckraSTMGMFKRYAsd------gANWARHIRHLFPRIIE 308 Caligus rogercresseyi
ACO11521  277 ges-----spyntspksPTYKYVERLTh-------qLYFSYLYSKTFMKMIS 316 Caligus rogercresseyi
CBI28196  451 -----------------ETQRIVKNYAgnrr--eptESFASLFYLLMVQMEP 483 wine grape

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