2GPR,1AX3,1GGR,1GLA


Conserved Protein Domain Family
PTS_IIA_glc
?
cd00210: PTS_IIA_glc 
Click on image for an interactive view with Cn3D
PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.
Links
?
Statistics
?
PSSM-Id: 238128
Aligned: 14 rows
Threshold Bit Score: 185.569
Created: 16-Aug-2001
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
Conserved site includes 23 residues -Click on image for an interactive view with Cn3D
Feature 1:HPr interaction site
Evidence:
  • Comment:interaction with phosphorylation donor HPr
  • Structure:1GGR; complex of IIA with HPr
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                     ####   ##                     ## ##     ###     ### #   # ##    
2GPR       10 VLAPCDGTIITLDEVEDEVFKERMLGDGFAINPKSNDFHAPVSGKLVTAFPTKHAFGIQTKSGVEILLHIGLDTVSLDGN 89  Mycoplasma capricolum
1AX3       15 FVSPITGEIHPITDVPDQVFSGKMMGDGFAILPSEGIVVSPVRGKILNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGE 94  Bacillus subtilis
1GGR_A     22 IIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE 101 Escherichia coli
1GLA_F     22 IIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE 101 Escherichia coli
131487    485 LFSPLAGEVLLLEQVADRTFASGVMGKGIAIRPTQGRLYAPVDGTVASLFKTHHAIGLASRGGAEVLIHVGIDTVRLDGR 564 Pectobacterium chr...
131486    479 ICSPMTGEIVPLIHVADTTFASGLLGKGIAILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGK 558 Escherichia coli
125944    484 LVTPTTGYLVDLSSVNDEHFASGSMGKGFAIKPTDGAVFAPISGTIRQILPTRHAVGIESEDGVIVLIHVGIGTVKLNGE 563 Streptococcus ther...
730418    464 IHSPIKGEVKALSEVKDGVFSAGVMGKGFAIEPEEGEVVSPVRGSVTTIFKTKHAIGITSDQGAEILIHIGLDTVKLEGQ 543 Bacillus subtilis
131500    501 LVSPITGDVVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEIVVHMGIDTVALEGK 580 Escherichia coli
131505    517 LAAPLAGEAVELTSVNDPVFSSEAMGKGIAIKPSGNTVYAPVDGTVQIAFDTGHAYGIKSDNGAEILIHIGIDTVSMEGK 596 Streptococcus mutans

Feature 1            #                               #  # 
2GPR       90 GFESFVTQDQEVNAGDKLVTVDLKSVAKKVPSIKSPIIFTNNGG 133 Mycoplasma capricolum
1AX3       95 GFTSFVSEGDRVEPGQKLLEVDLDAVKPNVPSLMTPIVFTNLAE 138 Bacillus subtilis
1GGR_A    102 GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDE 145 Escherichia coli
1GLA_F    102 GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDE 145 Escherichia coli
131487    565 YFTPHVRVGDVVRQGDLLLEFDGPAIEAAGYDLTTPIVITNSED 608 Pectobacterium chrysanthemi
131486    559 FFSAHVNVGDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDD 602 Escherichia coli
125944    564 GFISYVEQGDRVEVGQKLLEFWSPIIEKNGLDDTVLVTVTNSEK 607 Streptococcus thermophilus
730418    544 WFTAHIKEGDKVAPGDPLVSFDLEQIKAAGYDVITPVIVTNTDQ 587 Bacillus subtilis
131500    581 GFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD 624 Escherichia coli
131505    597 GFEQKVQADQKIKKGDVLGTFDSDKIAEAGLDNTTMFIVTNTAD 640 Streptococcus mutans

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap