1GCC


Conserved Protein Domain Family
AP2

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cd00018: AP2 
Click on image for an interactive view with Cn3D
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.
Statistics
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PSSM-Id: 237985
View PSSM: cd00018
Aligned: 23 rows
Threshold Bit Score: 56.1259
Threshold Setting Gi: 18652406
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
DNA binding
Conserved site includes 11 residues -Click on image for an interactive view with Cn3D
Feature 1:DNA binding site [nucleic acid binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1        ## # # #  #   # #              # #  #                                  
1GCC_A      1 KHYRGVRQRPW-GKFAAEIRDPak-------nGARVWLGTFETAEDAALAYDRAAFRMRG----SRALLNFPLR 62  thale cress
1351945   130 SQYRGVTFYRRtGRWESHIWDC----------GKQVYLGGFDTAHAAARAYDRAAIKFRG----VEADINFNID 189 thale cress
2281641    45 SKYKGVVPQPN-GRWGAQIYEK----------HQRVWLGTFNEQEEAARSYDIAACRFRG----RDAVVNFKNV 103 thale cress
NP_175524  45 TKFKGVVQQQN-GHWGAQIYAD----------HRRIWLGTFKSAHEAAAAYDSASIKLRSf--dANSHRNFPWS 105 thale cress
2129537   384 SIYRGVTRHHQhGRWQARIGRVa--------gNKDLYLGTFGTQEEAAEAYDVAAIKFRG----TNAVTNFDIT 445 thale cress
AAL77108    9 SGYRGVRERPN-GGFYAEIRSG----------DLRLSLGTYDTAHEAARAFDAAAWRLGR----LRRQINFQDV 67  barley
7489779   203 SKYRGVTLHKC-GRWEARMGQLl--------gKKYIYLGLFDSEVEAARAYDRAALRFNG----REAVTNFEPS 263 Zea mays
7489754   139 SIYRGVTRHRWtGRYEAHLWENscrregqsrkGRQVYLGGYDKEEKAARAYDLAALKFWG----PTTTTNFQVS 208 Zea mays
7489716   204 SRFRGVTQHKC-GKWEARIGQLm--------gKKYVYLGLYDTETEAAQAYDKAAIKCYG----KEAVTNFDAQ 264 Zea mays
4512700    85 KKHKGVRKKPS-GKWAAEIWDPs--------lKVRRWLGTFPTAEMAAKAYNDAAAEFVGrrsaRRGTKNGEEA 149 thale cress

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