4NJG


Conserved Protein Domain Family
queE_Cx14CxxC
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TIGR04508: queE_Cx14CxxC 
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7-carboxy-7-deazaguanine synthase, Cx14CxxC type
In the pathway of 7-cyano-7-deazaquanine (preQ0) biosynthesis, the radical SAM enzyme QueE is quite variable. This model describes a variant form in which the three-Cys motif that binds the signature 4Fe-4S cluster takes the form Cx14CxxC, as in Burkholderia multivorans ATCC 17616. The crystal structure is known.
Links
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Statistics
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PSSM-Id: 275301
Aligned: 11 rows
Threshold Bit Score: 380.201
Created: 10-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4NJG_A        23 YAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWP--- 99  Burkholderia mu...
WP_004189241   3 YTVKEIFYTLQGEGANAGRPAVFCRFAGCNLWTGREADRDGAVCRFCDTDFVGTDGENGGKFKDAASLAARIASLWP--- 79  pseudomallei group
WP_012971938   3 YWVKESFYTLQGEGAQAGRAAVFCRFSGCNLWSGREQDRDRAICRFCDTDFRGTDGEGGGRYRDADVLAEHLRALWP--- 79  Allochromatium ...
WP_010920995   3 YSVKEIFLTLQGEGGQAGKAAVFCRFSGCNLWSGREQDRAKAVCTFCDTDFVGTDGENGGKFATAEDLAAAVEAQWT--- 79  Caulobacter vib...
WP_013418786   2 YTVKEIFPTLQGEGAQVGRAAVFLRFAGCNLWTGQHKDKSKAFCRFCDTDFVGYDGPNGGKFETADQLADIVLGMWNslt 81  Rhodomicrobium ...
WP_011541648   3 YSVKEIFLTLQGEGAQAGRRAVFCRFAGCNLWTGREQDRAKAICRFCDTDFVGTDGTLGAKYRDAAALADVIAESWG--- 79  Sphingopyxis al...
WP_012069805   2 YSIKEAFYSLQGEGAHAGRPALFCRFTGCNLWSGSEKTRATSECQFCDTDFIGTNGQHGGKFKTAGQLRTHLDALWP--- 78  Marinomonas sp....
WP_012696605   3 YTVKEIFHTLQGEGVHSGRAAVFCRFTGCNLWSGRETDRAQATCQFCDTDFVGT-GPDGGKFACARELAGRIADSWA--- 78  Laribacter hong...
WP_011507336   2 YSVKEAFYTLQGEGARAGRASVFCRFTGCNLWSGRERDRAQSRCRFCDTDFVGTDGQNGGRFADAHALATHLHRLWP--- 78  Chromohalobacte...
WP_011952245   4 YAVKEMFLTLQGEGVQVGRRAVFLRFAGCNLWSGREEDRADAQCRFCDTDFVGLDGDNGGRYPHADALADKAIALWG--- 80  Sphingomonas wi...
WP_010939927   3 YRVKEIFHTLQGEGMRAGRAAVFCRFSGCNLWTGWAQDRPAAVCPFCDTDFVGTDGPGGGVFEDAATLAAAILAAFP--- 79  Desulfovibrio v...

4NJG_A       100 -AG-----EAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIP 173 Burkholderia mu...
WP_004189241  80 -AG-----EAYRFVVCTGGEPMLQLDQPLVDALHAAGFTIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVVP 153 pseudomallei group
WP_012971938  80 -TGagadaSDRPYVVCTGGEPLLQLDAPLIDALHGSGFEVAVETNGTRPAPPGLDWICVSPKAGATTVLIEGDELKLIYP 158 Allochromatium ...
WP_010920995  80 -GG-----PDDRLVVCTGGEPFLQLDDAAIAALHARGFQIAVETNGTITAPAGVDWICVSPKADAPVVQTSGQELKLVFP 153 Caulobacter vib...
WP_013418786  82 kGK-----TASPYVVCTGGEPTLQLDTPMIDALKKRGFTVAIESNGTRPAPRGLDWICISPKAGVPLAQREGNELKLVYP 156 Rhodomicrobium ...
WP_011541648  80 -PG-----SDDRYVVLTGGEPMLQVDDALIDALHARGFTIAIESNGTLPIPRSIDWICVSPKAGSELVQSSGDELKLVWP 153 Sphingopyxis al...
WP_012069805  79 -VG-----QGHKYVVFTGGEPALQLDNAIISEMKLYGYTIAIETNGTIALPDGIDWICVSPKTNKPLVVNKGDELKLVYP 152 Marinomonas sp....
WP_012696605  79 -GT-----GGTPYVVFTGGEPLLQLDEELIEAMHARGFEVGVETNGTIPAPPGIDWLCVSPKAGSGWVQKQGDELKLVYP 152 Laribacter hong...
WP_011507336  79 -GTdd--tAATPYVVFTGGEPLLQLDTALITAMRAHGFEVAVETNGTLTPPDGIDWLCVSPKGDAPLRITQGDELKLVYP 155 Chromohalobacte...
WP_011952245  81 -DL------AGAFIVMTGGEPLLQVDDALVAALKARGFETAVETNGTQPAPAGIDWICVSPKAGTDIVLRRGNELKLVWP 153 Sphingomonas wi...
WP_010939927  80 -YKtg--eGYRPYVVFTGGEPALQLDRPLIDILHAHGCEVAIETNGTVRLPEGIDWVTVSPKAGTRLAVTSGDELKLVWP 156 Desulfovibrio v...

4NJG_A       174 QDNQRLADYAKLDFEYFLVQPMD-GPSRDLNT------KL---AIDWCKRHPQWRLSMQTHKYLNIP 230 Burkholderia multivorans ATC...
WP_004189241 154 QDNQRLADYAKLDFEHFLVQPMD-GPSRELNT------RL---AIDWCKRHPRWRLSMQTHKYLNIP 210 pseudomallei group
WP_012971938 159 QPGLEPERFEGLGFRHFFLQPMD-GPQSNANT------RL---AVDYCKARPRWRLSLQTHKWLGIP 215 Allochromatium vinosum
WP_010920995 154 QEKAMPERFAALDFERFYLQPMD-GPDRDANT------QL---AVAYCLSHPQWRLSVQTHKYLGLP 210 Caulobacter vibrioides
WP_013418786 157 QTGALPQLFERLKFEHFFLQPMD-GPQHRDNI------EA---AIRYCMANPPWRLSMQMHKLVGIR 213 Rhodomicrobium vannielii
WP_011541648 154 QPGSDVAKLAALDFRHLLVQPLD-DRNAAANV------QA---CIDLVMADPRWRLSLQTHKSLGLR 210 Sphingopyxis alaskensis
WP_012069805 153 QSHLSPELFEALDFTNFYLQPMDqSHLTAEQIplldtqQA---TLHYCLSHPRWRLSLQTHKMLNID 216 Marinomonas sp. MWYL1
WP_012696605 153 QPGLLPETVELTGFSRYWLQPMD-GPEQTMHI------KA---AIGFCLLHPDWHLSLQNHKLAGIR 209 Laribacter hongkongensis
WP_011507336 156 QDDAPPANFTHLDFAHFFLQPMDlAPRGGQGT------TMt-dTVAYCLDHPQWRLALQTHKIAGID 215 Chromohalobacter salexigens
WP_011952245 154 QPGIDPAALEGWDFEHFLLQPMD-GAQLDEAR------AA---AIAYVMDHPRWRLSTQTHKVVGIR 210 Sphingomonas wittichii
WP_010939927 157 QQGICPESYESLAFTYLLMQPRD-GLGDAGRG------DAeseAVRWCLAHPRWRLCLQTHKYLGIP 216 Desulfovibrio vulgaris
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