Conserved Protein Domain Family
rSAM_mob_pairA

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TIGR04471: rSAM_mob_pairA 
radical SAM mobile pair protein A
Members of this family are the upstream member (A) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.
Statistics
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PSSM-Id: 275264
Aligned: 3 rows
Threshold Bit Score: 450.892
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_08418993    3 VCIKSQIQNMNLVIGCTIGCSYCYARNNVQRFHMIDDFEKPEYFPGKLRLMEKARPQIFLLTGMSDFSGWRAEWRDEVFA 82  Ruminococcaceae...
ZP_02424348    3 VCIKSLIKNMNIVVGCTIGCPYCYARNNCRRFHITDDFSVPEYMERKLRIIDTSRPHVWLMTGMSDFSDWKPEWNAEIFE 82  Alistipes putre...
WP_013282511   3 ICIKDQIQNMNLVIGCTVGCPYCYARNNTRRYHIIDDFEKPQFFQGKLRMMEKKKPQNFLLTGMSDLSGWHEEWREEVFK 82  Butyrivibrio pr...
ZP_08418993   83 KMERNPQHQYLFLTKRPKEIDFSTHLDNAWFGVTVTSCKEKDRIPALREHIRGGHYHATFEPMFDDIGPVDFTGIEWVVI 162 Ruminococcaceae...
ZP_02424348   83 RISSNPQHAYIFLTKRPDKISFSSDDENVWMGVTVTRSSEKRRIDDLKKNIKARHYHVTFEPLFDDIGEIDFEGIDWIVI 162 Alistipes putre...
WP_013282511  83 KIAENPQHQFLFLTKRPDLLSFETDLDNAWFGVTVTRKSELWRIDALRSNVKAKKYHVTFEPLFDDPGKVDLTGIDWIVV 162 Butyrivibrio pr...
ZP_08418993  163 GTETGRRKGKSISKPEWVWNLTDQAHALGIPVFMKEDLLPIMGEEQMIQELPTAFHKVLE 222 Ruminococcaceae bacterium D16
ZP_02424348  163 GTETGNRKGKSYSRPEWVLSIAEQAKAHGIPVFMKEDLLPIMGDERMIQELPEQFTRRIQ 222 Alistipes putredinis DSM 17216
WP_013282511 163 GTMTGAKSRTVKTDPRWVYSLTEQAHELNIPVFWKEDLVPIMG-EEMIQEMPDAFNKVLE 221 Butyrivibrio proteoclasticus
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