Conserved Protein Domain Family
pren_cyc_PirE

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TIGR04446: pren_cyc_PirE 
prenylated cyclic peptide, anacyclamide/piricyclamide family
Members of this protein family occur primarily in Cyanobacteria. They average about 50 residues in length and are the ribosomally translated precursors of peptide natural products whose modifications include cleavage, cyclization, and prenylation. Sequences are well-conserved in the N-terminal region. They are nearly invariant over the last eight residues, but hypervariable just before that stretch. A related family, often in a similar genome context, is TIGR03678.
Statistics
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PSSM-Id: 275239
Aligned: 17 rows
Threshold Bit Score: 68.1826
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_002762716  1 MKTKKLTPRNAAPVQRENTATVSRNG--NAIAQLdwgTFCVGedgngnceewYELPFAGDDAE 61  Microcystis aeruginosa
ADA63229      1 MTKKNIRPQQVAPVERETISTAKDQS--GQVQAQ---DNWLGe--------wIGIPFAGDDAE 50  Anabaena sp. BIR260
ADA63235      1 MTKKNIRPQQVAPVERETISTAKDQS--GQVTAQy--SNKPS----------DFSPFAGDDAE 49  Anabaena lemmermannii 1tu32s11
ADA63237      1 MTKKNIRPQQVAPVERETISTAKDQS--GRVTVQw--GNGTGldwklltggiSASPFAGDDAE 59  Anabaena sp. 202A1/35
ADA63241      1 MTKKNIRPQQVAPVQRETISNAKDQS--GQVTPHh--QPWHA------------APFAGDDAE 47  Anabaena sp. TR232
ADA63243      1 MTKKNIRPQQVAPVEREIISTAKDKS--GQVEAQ---VIQH-----------YLFPFAGDDAE 47  Anabaena sp. PH262
AED99431      1 MTKKNLKPQQAAPVQREINTTSSESGtsTGLTPH---QAYLG----------IPLPFAGDDAE 50  Planktothrix agardhii NIES-596
AED99445      1 MIKKNIRPQQSAPVQRQVTTTSCQGE--KALFAS---TECDIlt-------rQCTPFAGDDAE 51  Planktothrix agardhii NIES-596
WP_002753031  1 MKTKKLTPRNDATVQREINTTSSEGG--TGLTPS---MSGVD----------YYNPFAGDDAE 48  Microcystis aeruginosa
WP_004161254  1 MKAKKLTPRNAAPVQREINTTSSEGG--TGLTPL---ILGEGeg-------wNYNPFAGDDAE 51  Microcystis aeruginosa
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