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23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr This model identifies Cfr, a 23S rRNA methyltransferase, EC 2.1.1.224, responsible for a transmissible form of chloramphenicol/florfenicol resistance. It is closely related to RlmN (see TIGR00048), an adenine C2-methyltransferase that acts at the same site where Cfr acts as a C8-methyltransferase [Protein synthesis, tRNA and rRNA base modification] |
Jiyao W et al.(2023). "The conserved domain database in 2023.",