Conserved Protein Domain Family
MYXAN_cmx8
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TIGR04413: MYXAN_cmx8 
CRISPR type MYXAN-associated protein Cmx8
Members of this family occur only in CRISPR/cas loci of the MYXAN type, but are present in a minority of such systems. This protein appears to replace the MYXAN system Cas8a1/Csx13 protein (TIGR03485/TIGR03486), compared to which it shows similar length and composition but only about 12 percent sequence identity.
Links
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Statistics
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PSSM-Id: 275206
Aligned: 9 rows
Threshold Bit Score: 657.553
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ZP_10524551   34 EYKLHELPSSQHKAGLAGLYLIIDWLDKQDINKE------LIKRTQISEAGLKVTLTKKDVKDLFDEIYkpifirveddk 107 Leptospira kirs...
ZP_15567552   34 EYKLHELPSSQHKAGLAGLYLIIDWLDKQDINKE------LIKRTQISEAGIKVTLTKKDVKDLFDEIYkpilidiesks 107 Leptospira kirs...
ZP_18841066   18 DYQLAELPSSQHRAGLAGLVLIIRWLEGQREFTEkvkngaICKLTRLDDKGATLELNQTGLEYLFDEIY----------- 86  Microcystis aer...
ZP_07113793    8 PYTLAELSSSQHRSGLAGLVLMVQWLHRFQPWKQdg--saICEIDNLSDRGVTLRINQLGLQALLNEVY----------- 74  Oscillatoria sp...
ZP_02730337    2 RYDLSVLPTAFHKAGLAGLVLLIESLKQRRALTA------EETKCTVAATEVTVTFTEPLLQKLMDDLY----------- 64  Gemmata obscuri...
WP_015189437  18 DYQLAELPSSQHRVGLAGLVLILRWLERQPEFKEkvengaICQLNCLDDRGATLELNRAGLEALFDEIY----------- 86  Gloeocapsa sp. ...
WP_015353453  40 DYQLAELPTAQHRAGLAGLVLMLRWLERLPGAKPg-----TARLARLDDASARVELDPRGLQRLFDELY----------- 103 Myxococcus stip...
WP_015224030  10 SYRLAELPSPQHRAGLAGLVLMVQDIQKQEILQYyq--saLLDLDSLDEFGVTIRFNLEGLKALFDLTF----------- 76  Cyanobacterium ...
WP_013047540  17 EYSLDNLPSAQHKTGLAGLVLLLETMEEREMAP-------LPEYKENIDGTWTFQFTRKSFQAVFDELY----------- 78  Aminobacterium ...

ZP_10524551  108 irt-kgkgenkkdipplDLYSKKFETKIFIYPSKpkaklePNKVLIQEIDNPNPSs---------KKNRKL-YIyeeetk 176 Leptospira kirs...
ZP_15567552  108 qpkegtefttferkentTFYYYEIESKSLKKDKKtkteiqPIREIVKEILDKKSGk---------IKKIKS-YIyeeklq 177 Leptospira kirs...
ZP_18841066   87 -----------------DASLEEQERNQLLKKRTkev-iqPLREEEKEETDPKTNk---------TKTKKV-YI------ 132 Microcystis aer...
ZP_07113793   75 -----------------AASWEEKIEYKLREDKEtgeiiqPIRTEEVPDKDSKTGkvkidkktgqPKTKTA-YY------ 130 Oscillatoria sp...
ZP_02730337   65 -----------------DAREVEVAVKSKWQGAE-------VKREETVEEEVDGK----------KTRTKR-FI------ 103 Gemmata obscuri...
WP_015189437  87 -----------------AASAEEQERNQLLKNQRtkeviqPLREEEREETDPKTK----------KKKVKKvYI------ 133 Gloeocapsa sp. ...
WP_015353453 104 -----------------AARLEEKWEKKPRDGAR------PLREDVKVVRDKKGE----------TRRERY-FI------ 143 Myxococcus stip...
WP_015224030  77 -----------------GAFIEERSTETKIKNFD--------RVEEIEAKDDKSK----------IKIKKL-YY------ 114 Cyanobacterium ...
WP_013047540  79 -----------------DGENIIVESPSKWSGAS------PIEIREKEV-EKNGK----------KKTERV-FV------ 117 Aminobacterium ...

ZP_10524551  177 kkrkypnnidiepiktysieeekivyiYDHKYPFGSFL--SQYDKNKEn--GLWIKLWRDMMWsTIRGipttrneYKKYE 252 Leptospira kirs...
ZP_15567552  178 ekkeiddeei-dpireeevedvvtyyaYQMNYPLGSFL--HTFDKSID---NVWIKIWREMQW-LLRG-------YKQRQ 243 Leptospira kirs...
ZP_18841066  133 ---------------------------YPVVVPKGSFLsdPSYDKSSDgknGLWIKLWRDMVWsILRGvpatrkpFEARA 185 Microcystis aer...
ZP_07113793  131 ---------------------------YPMFVPQGAFLvdPQYDRSSDgknGLWIKLWRDALWaILKAkalsrnsFKARA 183 Oscillatoria sp...
ZP_02730337  104 ---------------------------YDQVQPKGAFF-----DNVFDgdkEIWRKLWRDMLWnIPRGrpttrepFNQRA 151 Gemmata obscuri...
WP_015189437 134 ---------------------------YPVVVPKGSFLsdPSYDNSADs-nGLWVKLWRDMVWnILRGvpatrkpFEARA 185 Gloeocapsa sp. ...
WP_015353453 144 ---------------------------YEVPVPRAGLL--LSMDPTASdrtGHWVKLWRDMLWsTLRGvpttrgpFISRA 194 Myxococcus stip...
WP_015224030 115 ---------------------------YSVVTPQGAFL--PYLDESAEgnnGIWIKLWRDMYWgIIRGvpatrnsFNSRA 165 Cyanobacterium ...
WP_013047540 118 ---------------------------YEITVPKGSFFk-GLFSEGPEgkkRL--ELWRDALWsTYKGkpasrgvYSERV 167 Aminobacterium ...

ZP_10524551  253 S----ENDPNIIKQWKIL--------SSLTDFKTLKSQYFIGAQKVNAESINFQDIHKHFFLLNFFPFTIQTYASRKmeY 320 Leptospira kirs...
ZP_15567552  244 Iy--eNPNKEVEIIWENF--------SKDKKENDLSKVLFLSAQNNNAEKVNFKETHTNKFLLHFWLFAAQPYAYWT--Q 311 Leptospira kirs...
ZP_18841066  186 Eg---QYNDDAIKVWQQLi-------QPEEFTVDLPSTYFLGAQANNAENIPFKDRARLQFLLHFWLFAAQIYVPEV--I 253 Microcystis aer...
ZP_07113793  184 Ne--lSDTKDVKDIWKNL--------ANPSSQIKLAGSFYLGVQEKNAEDIPFKDRGRYHFLLHFWFFVAQIYVPIKinI 253 Oscillatoria sp...
ZP_02730337  152 Sg---KPCKEGPNAWSELlkvhkartKKEFHTAALSSALFPGAQAVNAEAVPFEGRAEENLLLHFWPLTALLYVPQE--I 226 Gemmata obscuri...
WP_015189437 186 Eg---QYNEDAIKVWQQLi-------QPEEFTVDLPSTYFLGAQANNAENTPFKDRARFQFLLHFWSFAAQIYVPEV--I 253 Gloeocapsa sp. ...
WP_015353453 195 Lg---ESTSDAAKAWKLLt------aKRRRASVSLSSTELLGAMEHNAEGVSFEDLPRTAFLLHFWPYVTQVYVPRT--L 263 Myxococcus stip...
WP_015224030 166 NkdygAYSNDVVKQWTQL--------QNPDKTIGQSGNYYLGAMASNAENIPTKDNIAYQFLLNFAPFVFQVYRPTT--I 235 Cyanobacterium ...
WP_013047540 168 Qn---NPCSFVEKLWSSLi-------RKKGGIEDLAGSLLLGAEGFNAEGIPFKGLLHENVLLHFTPIACALFVVRNfmV 237 Aminobacterium ...

ZP_10524551  321 DSNIKDYKL------ADNGYIVCIPDILRLKSFCEYFPDYMNQ-RSLDKAGY---RPREAITFLPQIAGLDSLNKFHLIL 390 Leptospira kirs...
ZP_15567552  312 RKEKDKYKT------DEHGFIIAVPDIAKLESFNFIFNELIKN-QNNEIKKHpikRPEQAVVYLPRLAGFLLLKNIHDIL 384 Leptospira kirs...
ZP_18841066  254 DNEGKR---------NFAGYAIAIPDIFKLKRFCERLSRLLSE-RSIEKSGY---LPRDCIVDLAIESALDIMMRLTERL 320 Microcystis aer...
ZP_07113793  254 EKEKESKKHqe--niDFWGYVIAIPDIANLKFFCDEFFEFLSS-REIKPFKF---LPRECIIDLQLEAALEMSKRLKLQL 327 Oscillatoria sp...
ZP_02730337  227 ERDGSTNL-------PASSYTVAVPDVSDLCEFVTEYPKLLTG-LSAEVRGY---RPAQAVIDLPAEGALAFLEDLAVLT 295 Gemmata obscuri...
WP_015189437 254 DNEGKRN---------FVGYAIAIPDVAYLAWFCDELQDILQH-RSIEKSGY---RPRDCIVDLAIESALDMMKRLRDRL 320 Gloeocapsa sp. ...
WP_015353453 264 VVKERRVLS------DPRGYALAIPDVARLRTFCEVLPRALLG-RGTALRGF---RPQESMVDLAVESALMTGQLLRRRL 333 Myxococcus stip...
WP_015224030 236 NKDGKR---------EFGSYALAIPDVANLERFCFSFSKLLKQ-RNNDKLGY---SPKESIIDLAEESALNFF-ILEDRI 301 Cyanobacterium ...
WP_013047540 238 KKGNRDNKGtysvewDENGYVFVMPEITKIKPYLGELRKWFQNdPEKETKSF---RPSSSIIDLPEESGLEFLSAISGRR 314 Aminobacterium ...

ZP_10524551  391 KRTLGNS--FHEILHAQDIIHCE---KDDKNIR-----IRNSIRIKPNFDFENKVMQY-----KK------LYHNYHFQK 449 Leptospira kirs...
ZP_15567552  385 KKKIHSD--YSDVVFGIDLFHYDyewKKGKAIKnrasiFKGYTRIKPNIDLENKAANI-----KK------LYKNFFFQK 451 Leptospira kirs...
ZP_18841066  321 TQSTGEQk-TASTVLGIDVIHTE---KQGNNIR-----ILGASRLNPENLMINEYIRI-----RN------QYWSPLFRK 380 Microcystis aer...
ZP_07113793  328 NKSESKKs-MSDLVNAIDIIHAH---RPKDDTK-----FIYIGRFLPTMEMANEYEAI-----KN------SLWSPTFRH 387 Oscillatoria sp...
ZP_02730337  296 RLEIEAGk-LRFSIGAVEYLHLV---KAGNNVK-----LMAAGRVAPDQRLLVGYRAI-----VRptgtapHYRNSLFRR 361 Gemmata obscuri...
WP_015189437 321 TQTIGEKtgIASTVFGIDVVHTE---KQGNNIR-----LLSVTRLDPEEAMLDRYVQI-----RN------NYWSPLFRK 381 Gloeocapsa sp. ...
WP_015353453 334 SKAEGALa-YSSLVWGYDVFHLG---KDGNNVR-----THGASRFEPEVEMVDAYAAL-----QG------SLKDALFRR 393 Myxococcus stip...
WP_015224030 302 SRDIGEQs-TKKSILGVEVIHTE---KVGNNVK-----FYGFNYLEPITTQTDKYKQI-----KD------KYWCPWFRK 361 Cyanobacterium ...
WP_013047540 315 LETEG----VFDRVEGVEYYHMT---KKGNSVK-----LLSSSRIPVSVPILNEYNSIvsaggRK------KPLNFLYKT 376 Aminobacterium ...

ZP_10524551  450 EIIQNLLSN--------------KSELNGFYELFKNY--------PYEEFfKFgan-vrGEIGFKTDAKTYFEE--QEIK 504 Leptospira kirs...
ZP_15567552  452 QLLQNIFDE--------------KEELDSFYSLFCTR--------EYEYFfNH------WEGEFKPDAEIFFEE--KEIK 501 Leptospira kirs...
ZP_18841066  381 QRLLNLVNH--------------SPWYSGFDSLLCTI--------PYKQI--T------ENEYFKHDVREALNN--EESA 428 Microcystis aer...
ZP_07113793  388 QRLLNLVRD--------------KKWYTGFDSLLCTI--------PYEQTmEN--------DYFRHDSRESFKY--EVED 435 Oscillatoria sp...
ZP_02730337  362 GLLLALLDG--------------ESWYQPFGRSFVTFdagvfirqPRKDD-EK------GPPQFASDASKKFRH--LTTL 418 Gemmata obscuri...
WP_015189437 382 QRLLNLVNH--------------SPWYVGFDSLLCTL--------PYEQI--T------KNDYFKHDVYEAFKN--ENTM 429 Gloeocapsa sp. ...
WP_015353453 394 TCLLNLVKQ--------------RPWYAGFDRVFATS--------PHEVT--L------GAMAFRQDARLSLER--HMHM 441 Myxococcus stip...
WP_015224030 362 QRLKNLLNSivytdsqeskyeekPPWF-GFDDLLSRV--------PRKWL-ET------GKDYFSHDARILFNE--EILN 423 Cyanobacterium ...
WP_013047540 377 LRIRNLLNG--------------THWHVGMEGILETY--------PSEFFiWSregsprNIPFFGLDINKKFKEiaQKLY 434 Aminobacterium ...

ZP_10524551  505 FKGEQ--KM--SEDGNVPKTIELL------VHQIIRTYIFSKLEFKHQIIWDKDKKVlwsksrn------tpanddDYKN 568 Leptospira kirs...
ZP_15567552  502 FKGEQ--KM--SEDGNVPKTIELL------VHQIIRTYILSKLDSKYELKWDEHGKV-------------------FSEK 552 Leptospira kirs...
ZP_18841066  429 MTEQT--ET-----KMEPN-IEKL------VFELVKNYVKRKLYSKYELTWS---NVkgnpk----------eekeYNEK 481 Microcystis aer...
ZP_07113793  436 MTEET--EQdlGTEVAEYS-CERL------VLRLVKSYVLSKLEGKYQLKWK---DVqgsp-----------keseYRDK 492 Oscillatoria sp...
ZP_02730337  419 FTQTL--EMavGDSVQPPKPLELL------VEQVIKSYLLGKAKAKCNIDKKTKLSAlgkd-----------eqkkVYDK 479 Gemmata obscuri...
WP_015189437 430 ----T--EK--NASVTEIN-IEQL------VFRLVKEYVRAKLKSKYGLEWKKEWEIsgfasdeqkearnksgygnYAEK 494 Gloeocapsa sp. ...
WP_015353453 442 DSNAS--SP--SAP-----SLEQL------VFQVARHYVLVKLERKHKLRWD---AVkddps----------lkktYNEK 493 Myxococcus stip...
WP_015224030 424 SQGVT--EM--SEKNTKIRDYASI------IYQVCQSYVMGKLENKYELKWD---KIkgnsk----------lekdYNDK 480 Cyanobacterium ...
WP_013047540 435 YIEQEakEM--EENGVNSNLIDHTerlaakVRNIVRNFVISELKSRPKIKIPGGKTHleqtkeds----flaypedYLAE 508 Aminobacterium ...

ZP_10524551  569 KSKIAKDAFLAIRSRKDREDFINYFTSTICSVPHKL--G-------EEEYIKLAESLYnaeEDTGWEKIRALSMLALSAN 639 Leptospira kirs...
ZP_15567552  553 KEKIAKDAFLAIRSRKDREDFINYFTSTICSVPHKL--G-------EEGYIKLAESLYnaeEDTGWEKIRALSMLALSAN 623 Leptospira kirs...
ZP_18841066  482 KEKIAKSAFLDVRSRTEKMDFINYFVSSLCSVPQHM--K-------SEDYVSLTKALY---EDT--ERIRTLTLLALSAN 547 Microcystis aer...
ZP_07113793  493 KAKIAKSAFLDIRSRSEKSDFINYFASTICSVSQRM--N-------ESDFEKLTRDLY---EDT--DKVRTLTMLALSAN 558 Oscillatoria sp...
ZP_02730337  480 KRDIAAEAFLAARSRRDQ-DFVKYFSEVICSAGTYFdkK-------TSDFQVFATALN---DPNKTDSIKALTLLALSAN 548 Gemmata obscuri...
WP_015189437 495 KEKIAKSAFLDVRSRTESIDFINYFVSSLCSVPQHM--K-------SEDYVSLTKALY---DDT--ERIRTLTLLALSAN 560 Gloeocapsa sp. ...
WP_015353453 494 KEVVARDAFLAVRSRSGQ-DFIAYFAGTLCSVPQHL--P-------VDQFVRLSQALQ---TQH--EDMKTLTLLALSAN 558 Myxococcus stip...
WP_015224030 481 KNKIVNEAFLAVRSRTEKQAFIDYFVSTLYPFV-----K-------KEEFAQFAEDLF---KKT--DEIRALTLLALSSQ 543 Cyanobacterium ...
WP_013047540 509 LKKICTGAFLALRGRSGT-DIAEFFTGTLCAIPQFL--KndfknegKDDYLLMAKSLV---DPKEREKIKLFAMLALSAC 582 Aminobacterium ...

ZP_10524551  640 S 640 Leptospira kirschneri serovar Bim str. 1051
ZP_15567552  624 S 624 Leptospira kirschneri str. H2
ZP_18841066  548 S 548 Microcystis aeruginosa PCC 9808
ZP_07113793  559 S 559 Oscillatoria sp. PCC 6506
ZP_02730337  549 S 549 Gemmata obscuriglobus UQM 2246
WP_015189437 561 S 561 Gloeocapsa sp. PCC 7428
WP_015353453 559 A 559 Myxococcus stipitatus
WP_015224030 544 F 544 Cyanobacterium stanieri
WP_013047540 583 S 583 Aminobacterium colombiense
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