Conserved Protein Domain Family
SecA2_Bac_anthr

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TIGR04397: SecA2_Bac_anthr 
accessory Sec system translocase SecA2, Bacillus type
Members of this family always occur in genomes with the preprotein translocase SecA (TIGR00963) and closely resemble it, hence the designation SecA2. However, this appears to mark a different type of accessory Sec system SecA2 (TIGR03714) from the serine-rich glycoprotein type found in Staphylococcus and Streptococcus, and the actinobacterial SecA2 (TIGR04221). This type occurs in species including Bacillus anthracis, Geobacillus thermoglucosidasius, Solibacillus silvestris, etc. [Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 275190
Aligned: 8 rows
Threshold Bit Score: 1375.2
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_08784594    4 ISRIKQnESFREVKKYYALVEKINNLENEYEALSDDELKGKTIEFRNRLEKGETIHDLTVEAFATVREASKRVLGMRHFD 83  Ornithinibacill...
WP_013399911   5 VKKLLN-SDERRLKRYYKIVDHINALEPKFAKLSDQELREKTAYFKNELANGKTVFDIQAEAFAVVREAAKRVLGMRHFD 83  Geobacillus sp....
WP_011888224   5 LKRAIGyTNERQLKKYMRVVEQINRMEPQMEKLTDAELRRKTDEFKEQLASGKSVNDIQVEAFAVVREVAKRVLGMRHFD 84  Geobacillus the...
WP_000935179   5 VKKLLGdSQKRKLKKYEQLVQEINNLEEKLSDLSDEELRHKTITFKDMLRDGKTVDDIKVEAFAVVREAAKRVLGLRHYD 84  Bacillus anthracis
WP_012960495   5 IKKLIGdSQQRKIKSYEKVVAKINELEPHMEKLSDEELRQKTSLFKEQIQNGTSINELKAEAFAVVREASKRVLGLRHYD 84  Bacillus pseudo...
WP_012292886   5 FKSNKEqTSARQLKRYYKIVDQINNLEQKYVDKSDAELREMTFIFKNQLEQGEPITSIIPDAFAVVREASKRVLGMRHFD 84  Lysinibacillus ...
WP_013524685   5 VKQLFd-ESAREVQRLAKLAAQINEWEPTISSLSDEQLRQKTVAFKERLERGETLDDIKTEAFAVVREAARRVLGLRHYD 83  Geobacillus
WP_012726876   5 VKQLTNd-QSRRLKAYERRVARINELETTMKALSDDEMRTYTETLKARLLDGKKVDDIAEEGFALVREASVRVLGMRHYD 83  Exiguobacterium...
ZP_08784594   84 VQLLGGIVLLHGNISEMATGEGKTLVASLPSYLVALEGKGVHVITVNDYLAQRDRDIVGQIHEFLGLKVGLNIPGLGTQE 163 Ornithinibacill...
WP_013399911  84 VQLIGGLVLAEGNIAEMATGEGKTLVASLPSYLRALEGKGVHVITVNEYLARRDRELIGQIHEFLGLTVGLNLPMMETEE 163 Geobacillus sp....
WP_011888224  85 VQLIGGLVLAEGNIAEMATGEGKTLVASLPSYLRALEGKGVHVITANDYLAKRDRNLIGQIHEFLGLTVGLNLPLMSPQE 164 Geobacillus the...
WP_000935179  85 VQLIGGLVLLEGNIAEMPTGEGKTLVSSLPTYVRALEGKGVHVITVNDYLAKRDKELIGQVHEFLGLKVGLNIPQIDPSE 164 Bacillus anthracis
WP_012960495  85 SQLIGGLALSEGNISEMPTGEGKTLVASLPSYLRALEGKGVHVITVNEYLASRDREIIGPVHEFLGLKVGLNVPMISPEE 164 Bacillus pseudo...
WP_012292886  85 VQLIGGLVLTEGNIAEMPTGEGKTLVASLPSYVRALEGKGVHVITVNDYLAKRDYELVGQIHRFLGLTVGLNIPMMEADE 164 Lysinibacillus ...
WP_013524685  84 VQLMGGLAMHEGNIAEMQTGEGKTLAATLPSYLHALLGKGVHIITANEYLARRDCEQMGRVFRFLGLTVGLNVSQMTASE 163 Geobacillus
WP_012726876  84 VQLIGGFALLEGNISEMPTGEGKTLVAALPSYVKALEGKGVHVITVNDYLARRDAEQIGKIHDFLGLTVGLNVPDIEADE 163 Exiguobacterium...
ZP_08784594  164 KQAAYNCDITYGVGTEFGFDYLRDNTVNELSQKVQRPYHYAIIDEIDSVLIDEAKTPLIIAGKDKPSGRLYKVCASVIKS 243 Ornithinibacill...
WP_013399911 164 KKAAYQADITYGIGSEFGFDYLRDNMVYDISQRVQRPFHYAIIDEIDSILIDEAKTPLIIAGKTGVSSELSYLCARIVKT 243 Geobacillus sp....
WP_011888224 165 KKQAYQADITYGIGTEFGFDYLRDHMVYDASDKVQRPYHYAIIDEIDSVLIDEAKTPLIIAGKTRSSTELHYIAARLVKR 244 Geobacillus the...
WP_000935179 165 KKLAYEADITYGIGTEFGFDYLRDNMAASKNEQVQRPYHFAIIDEIDSVLIDEAKTPLIIAGKKSSSSDLHYLCAKVIKS 244 Bacillus anthracis
WP_012960495 165 KKLAYDADITYGVGNEFGFDYLRGNMVYATSQRVQRPYHFAIIDEIDSVLIDEAKTPLIIAAKTQVSPNLYHICAKVARS 244 Bacillus pseudo...
WP_012292886 165 KKEAYNADITYGVGTEFGFDYLRDNMSYSLADKVQRPYHFAIIDEVDSVLIDEAKTPLIIAGKMPSKDELHRIAAMLAKR 244 Lysinibacillus ...
WP_013524685 164 KKEAYAADITYGTGTEFGFDYLRDNMVYRLEDKVQRPLYYAIIDEIDSILIDEARTPLIIANKSGIGAELFPIMARIVRT 243 Geobacillus
WP_012726876 164 KRSAYQADITYGVGTEFGFDYLRDNLVHKPEERVQRPFHFAIVDEVDSILIDEAKTPLIIAQKDRSHIRLKQLAQQIISE 243 Exiguobacterium...
ZP_08784594  244 LKEEEDYTYDLELKTVNFTEKGLNKCEKVFGIPNLFDLEHSSLFHSLLQALRARVLYKRDVDYIVEDGEIKLVDMNTGRI 323 Ornithinibacill...
WP_013399911 244 LERDVDYYYDEETKATNLTEEGIAKIERGFGIDNLYDVEHQTLYHYIIQALRAHVLFQRDVDYIVRDGKIVLIDMFTGRP 323 Geobacillus sp....
WP_011888224 245 FEREVDYIYDGETKTVNLTDEGIEKVEKAFGIDNLYDAEHQVLYHYVIQALRAHVLFQRDVDYIIRDGKVLLVDAFTGRV 324 Geobacillus the...
WP_000935179 245 FQDTLHYTYDAESKSASFTEDGITKIEDLFDIDNLYDLEHQTLYHYMIQALRAHVAFQCDVDYIVHDEKILLVDIFTGRV 324 Bacillus anthracis
WP_012960495 245 FKENDDYMYDPLLKAASLTDNGITKIERAFGVDNLYDLEHHTLYHFMIQALRARVMFKLDVDYIVKEGEIQLVDMFTGRI 324 Bacillus pseudo...
WP_012292886 245 FKKDEDYDFDDETKATSLTDKGIEKIEAAFNVENLYDLEHQTLFHYVIQAVRAHVMFKRDVDYIVKDDKIELVDMFTGRI 324 Lysinibacillus ...
WP_013524685 244 FEEGKEYERSPETKQIFLTEEGAQKIERAFGIDNLYDWEHHVLLHHAMQSLRAWFIMRRDVDYIVKNGKVMIVDPFTGRV 323 Geobacillus
WP_012726876 244 FEET-DYEVDLESKSATFTEEGIVKIEELFAIDNLFSASHQVLYHYLVQALRANVLFELDVDYIVREDKIELIDLFTGRI 322 Exiguobacterium...
ZP_08784594  324 MEGRSLSNGLHQAIESKEGLVNTEENKTMALITVQNYYRMYPLLSGMTGTAKTEESELRETYGMNVVQIPSNKPNQRVDM 403 Ornithinibacill...
WP_013399911 324 MEGRSLSHGLHQAIEAKEGLELTEENKTQAAITIQNYFRLYPILSGMTGTAKTEEKEFQTLYGMDVVQIPTNKPVIRVDE 403 Geobacillus sp....
WP_011888224 325 MEGRSLSDGLHQAIEAKEGLEITEENKTYASITIQNYFRMYPILSGMTGTAKTEEKEFQRIYGIDVIPIPTNRPKIRVDL 404 Geobacillus the...
WP_000935179 325 MDGRSLSDGLHQALEAKEGLEITEENQTQASITIQNFFRMYPALSGMTGTAKTEEKEFNRVYNMEVMPIPTNRPIIREDK 404 Bacillus anthracis
WP_012960495 325 MEGRTFSDGLHQALEAKEGLEITEENKTQASITIQNYFRMYPNLCGMTGTAKTEEREFRMVYGMDVIQVPTNKPRIREDR 404 Bacillus pseudo...
WP_012292886 325 LEGRSLSDGLHQAIEAKEGVTITDENKSQAQITIQNYFRMYPKLSGMTGTAKTQEKEIREVYGMEVVQIPTNRPRQRVDQ 404 Lysinibacillus ...
WP_013524685 324 MEGRSFSDGLHQAIEAKEGVEITEENDIQATITIQNYFRMYEKLAGMTGSATPSKEEFWQTYRLRVITIPTNRPSRRTDW 403 Geobacillus
WP_012726876 323 MEGRSLSEGLHQALEAKEGVTITEENKTTAEITIQHYFRMYPLVGGMTGTAQTSRQEFLKTYNMDVVQVPTNRERQRVDH 402 Exiguobacterium...
ZP_08784594  404 SDRVFMTKEQKYDFLLKEVKERHQTGQPILIGTTSILQSEEVAKLLDREQLEYQLLNAKSVQQEAKLISLAGQKDRITIA 483 Ornithinibacill...
WP_013399911 404 PDRVFLTIDQKYKAVAKEVKRVHETGQPVLIGTTSILQSEKVAKYLEAENLPFRLLNAKTIEQEAQLIALAGQKGQITIA 483 Geobacillus sp....
WP_011888224 405 PDRVYMTRHDKYVAVAKEVKRRHESGQPVLIGTTSILQSEEVAKYLDQEQVPYELLNAKTVEQEAEVIARAGQRGRVTIA 484 Geobacillus the...
WP_000935179 405 KDVVYVTADAKYKAVREDVLKHNKQGRPILIGTMSILQSETVARYLDEANITYQLLNAKSAEQEADLIATAGQKGQITIA 484 Bacillus anthracis
WP_012960495 405 NDLVFATSEDKYKAVAAEVEERHKTGQPVLIGTTSIIQSETMASYLDDKKIPYELLNAKSVEKEVQLISLAGQKNQVTIA 484 Bacillus pseudo...
WP_012292886 405 PDIIFSTQEAKYKYVAAETKKRHEKGQPILIGTTSILQSETVADYLKKEKLTFQLLNAKTVEQEVELISQAGQKGRITVA 484 Lysinibacillus ...
WP_013524685 404 DDLVYQTYEAKVRKIIDEVKKMNAIGRPVLIGTTSVAQSERLSEAFSKAGIPHHLLNAKTEEEEARIIATAGQKGQVMIA 483 Geobacillus
WP_012726876 403 PDRIFMTTEQKYAAVTEKVAELHTTGRPILIGTTSIAQSEAISKHLKKKRIEHDVLNAKTVAQEADIIADAGQFGKVTIA 482 Exiguobacterium...
ZP_08784594  484 TNMAGRGTDIMLGEGVAELGGLHVIGTERNESRRIDNQLKGRSGRQGDPGSTQFIISVEDYLFIRYAADELERMKPKFKA 563 Ornithinibacill...
WP_013399911 484 TNMAGRGTDIMLGEGVAELGGLFVLGTERHEARRIDNQLKGRAGRQGDPGRSQFFISLEDDMFRRFAKEETEKWMKKAKT 563 Geobacillus sp....
WP_011888224 485 TNIAGRGTDILLGEGVNELGGLHVLGTERHESRRIDNQLKGRAGRQGDPGSSQFFISLEDDMFRRFAAEETEKLKAKLKT 564 Geobacillus the...
WP_000935179 485 TNMAGRGTDILLGEGVHELGGLHVIGTERHESRRVDNQLKGRAGRQGDPGSSQFFLSLEDEMLKRFAQEEVEKLTKSLKT 564 Bacillus anthracis
WP_012960495 485 TNMAGRGTDIMLGQGVHELGGLYVIGTERHESKRIDNQLRGRSGRQGDPGESQFIISIEDELLLRFGGEMIEAFKEEIKT 564 Bacillus pseudo...
WP_012292886 485 TNMAGRGTDIVLGDDVHELGGLYVIGTEKHESRRVDNQLRGRSGRQGDIGESRFILSIEDDMFRRYAKEEVEKFSAKMVV 564 Lysinibacillus ...
WP_013524685 484 TNMAGRGTDILLGEGVKELGGLHIIGTERHESHRIDMQLRGRAGRQGDPGSSQFIISLDDDLFRLYDQDELKKWKSKVET 563 Geobacillus
WP_012726876 483 TNMAGRGTDITLDAKAKEAGGLFVIGTERHESKRVDNQLRGRSGRQGDPGATEFFVSLEDEIVKRYAAQKLERVEKKLKP 562 Exiguobacterium...
ZP_08784594  564 NEIGEITSSNVHKFVETAQKISEGIHYQFREYNLKLENVTNKQRDIVYQLRDKLLE--EE-NAIQF-VMKQTADLPKKLI 639 Ornithinibacill...
WP_013399911 564 DENGEILNKEIHEFVDRVQRICEGNSFSIREYNLKLDDVLNDQRTAVYRLRNRILE--GD-RLIPL-VIDMLHSYVPYEI 639 Geobacillus sp....
WP_011888224 565 DETGCILNNDIHEFVDKVQRIVEGMNFSVREYNLKLDDVMNEQRNVIYQIRDRVLE--EN-DRVAL-VVPMIRSACDRIV 640 Geobacillus the...
WP_000935179 565 DETGLILTSKVHDFVNRTQLICEGSHFSMREYNLKLDDVINDQRNVIYKLRNNLLQ--EDtNMIEI-IIPMIDHAVEAIS 641 Bacillus anthracis
WP_012960495 565 DDNGLVQNENINKLVDKIQKMSEDHNYSAREYTLKLDDIINEQREVIYKLRNKLLE--SE-NNFDT-VREMIDTTWKDYV 640 Bacillus pseudo...
WP_012292886 565 DEQGIIQNKEVQELIDRTQRIVEGSQYGMREYNLKLDDVINDQRTVLYGLRDKILA--GE-DLMGE-LKKMLHETVDFAV 640 Lysinibacillus ...
WP_013524685 564 DETGRIVSPDPIKFVQKVQTTIENAHYSARLHLLKLDTVIDQQSKVIYHMRDRVLAlkQA-EVLSE-LLRHIQRYITQTI 641 Geobacillus
WP_012726876 563 SATGEVSSKDAIEIIEYAQTTIEGLGVSIRDYLFKLDDVLNEQRNIIYTIRNQAVN--ADaDAITKnVLGMMRLALENSI 640 Exiguobacterium...
ZP_08784594  640 QTFCEEDSLPEEWDLERLSEELNKISLVPFQL--EEKEFQSDEELIDFVKDHFKQNLEELSQYEDNEEIQMNAKGVVLFV 717 Ornithinibacill...
WP_013399911 640 EQHCPADMLPEEWDLEKLTEQLREIIPFPAVQ--LSGNINDIEDVKSNVQHSLEQYIHYLETMNDAEQVKAEIRPSLLSI 717 Geobacillus sp....
WP_011888224 641 DAYALSEQIPEEWDVRRMTEELNRIVYRTPIT--FDQPPADLEDVKRKVAEAVESYVALLEKKKAHTQLQTLLKSVMLTV 718 Geobacillus the...
WP_000935179 642 KQYLVEGMLPEEWDFASLTASLNEILSVENMPslSANNVHSPEDLQSVLKETLSLYKERVNELDSNTDLQQSLRYVALHF 721 Bacillus anthracis
WP_012960495 641 DHYCADELLPEEWNLEELTQRIQLILP-TFKG--FTQRPDEKKEVQAYITATYEQFIGDVEPLHEQEKIRIQIDRILLSN 717 Bacillus pseudo...
WP_012292886 641 LDAAPEDVSSIDWDYDRMEHALNSLFI-TPVT--IDREVGKVKQILADIQPSEQELLNHMEKFAENERVIEVLPQIMLSY 717 Lysinibacillus ...
WP_013524685 642 DRYCPENVFFEEWNIEGLHNELRRAFF-QFVYpiDDLRHKQKEEIAQLVWDEYKSLEAALTDLPCDEEQTMRLKHLMVET 720 Geobacillus
WP_012726876 641 DMHVSDELVPEEWPIDELKDDLRYLTMQEP-T--WAKDIADTRELKDALNDWMEAIIATTASRLEQDDIVLFAKESLLRA 717 Exiguobacterium...
ZP_08784594  718 IDTLWKKHLDTMNQLKEGIGIRQYQQEDPVQLYEKEGYKLFETLFNDIEYEIATRL 773 Ornithinibacillus scapharcae TW25
WP_013399911 718 VDYYWLNHLDAMERLKEGIGLRFYSQEDPIRQYQREGFELFVYMYHQIEADICRRL 773 Geobacillus sp. Y4.1MC1
WP_011888224 719 IDDYWMRHLDQMALLKEGIGLRHYQQEDPIRLYQKEGFEMFKAMYEVIEKEISVHT 774 Geobacillus thermodenitrificans
WP_000935179 722 LDQNWVNHLDAMTHLKEGIGLRQYQQEDPTRLYQKEALDIFLYTYGNFEKEMCRYV 777 Bacillus anthracis
WP_012960495 718 LDIHWTQHLEEMNRLKEGIGLRSYGQEDPMRIYTREGFELFTMMYKTLQRNSSIQY 773 Bacillus pseudofirmus
WP_012292886 718 IDSGWVRHLEAMTHLKEGIGLRHYQQEDPMRIYQREGLELFGKNFQELRRSIIIEI 773 Lysinibacillus sphaericus
WP_013524685 721 IDAHWIRHLNQLNLLKEGIHLRSYGQEDPYRAFEMDAYREFVALQQAIDAGICTTA 776 Geobacillus
WP_012726876 718 VDMKWTDHLTTMSGLKEGIGLRSYGQEDPSRQFGKEGLEIFEQTYINIARDVTTEL 773 Exiguobacterium sp. AT1b
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