Conserved Protein Domain Family
TOMM_nitrile_2

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TIGR04351: TOMM_nitrile_2 
putative TOMM peptide
Members of this family of short peptides average about 110 amino acids in length, with greatest variability in the last thirty. The conserved region resembles the alpha subunit of nitrile hydratase, as with the NHLP leader peptide domain (TIGR03793), and members usually are found near a cyclodehydratase (maturase) enzyme, marking these as like thiazole/oxazole-modified microcins (TOMM), but these precursor forms lack the GlyGly cleavage motif that marks the clear end of a leader peptide region. Genomes with this system include Streptomyces clavuligerus ATCC 27064, Verrucosispora maris AB-18-032, and Kitasatospora setae KM-6054.
Statistics
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PSSM-Id: 213964
Aligned: 5 rows
Threshold Bit Score: 73.2952
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_08214690   35 WLVELMARTWLEPALADRYRTDARSVLDEYGYTLPVGAQAPALPDTPV 82  Streptomyces clavuligerus ATCC 27064
WP_013003891  30 RFMELVAQAWLEPELSRRYQVDARSVLDEFGVTLAQGQQPPSLPENPV 77  Streptomyces scabiei
WP_013733761  15 KFAKIVSSAWSDTEFADRYQNTPYEVLAEHGIDYPAAVAPPLLPPKPS 62  Verrucosispora maris
WP_013733760  11 RFARLVADAWSDPTLANRYQLDPAAVLAEYGIVLGAGDEIPDLPPAPG 58  Verrucosispora maris
WP_014135875  46 RFAELVVRTHLEPGLRLRYLEEPAEVLAEFGLSLPEGATAPVLPGGGA 93  Kitasatospora setae
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