Conserved Protein Domain Family
heavy_Cys

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TIGR04289: heavy_Cys 
eight-cysteine-cluster domain
In this domain of about 50 residues, eight of twelve invariant residues are Cys. Proteins with this domain tend to have N-terminal signal sequences, suggesting an extracytoplasmic location for this domain.
Statistics
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PSSM-Id: 275107
Aligned: 12 rows
Threshold Bit Score: 54.0099
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAL80724     134 ECKSDLDCKAGGCSGELCGPRNe--sLYSPCVYREWYECIKyt-qCGCYLGVCTW 185 Pyrococcus furiosus DSM 3638
XP_001744658 461 KCETAADCVVSGCSGEVCAAED----VATTCELLDFRPAGA----CSCVDNQCVW 507 Monosiga brevicollis MX1
WP_010884814 153 ECKSDSDCKTGGCSGELCLKKNe--tAFSTCIYREWYECLKlt-kCGCYNGFCTW 204 Pyrococcus horikoshii
WP_015849884 141 ECESDSDCATGGCSGEVCAPKEvakeIVTPCVYREWYNCLRlt-qCGCYNGLCTW 194 Thermococcus sibiricus
WP_010868446 137 ECKADSDCKAQGCSGEACTPKNe--tVFSICIYREWYKCLNlt-sCGCYHGTCSW 188 Pyrococcus abyssi
WP_013905493 142 ECRSDADCATGGCSGEICTTRKgakeIVSICVYREWYDCLKlt-tCGCYNGYCMW 195 Pyrococcus yayanosii
WP_013467816 142 ECSKDSDCSTGGCSGEICTTREnatkVVSICVYRDWYECLKlt-sCGCVNGVCTW 195 Thermococcus barophilus
WP_014122765 133 ECKSDSDCATGGCSGEVCAPKVvvgrIATPCVYAPWYQCFQlt-sCGCVNGTCSW 186 Thermococcus sp. AM4
AIG98199     139 ECKSDADCKAAGCSGQVCAGVGe--qIVTTCEWRECFDAAKygmrCGCINNQCQW 191 Archaeoglobus fulgidus DSM 8774
WP_011849937 156 ECKSDADCVRDGCSGEVCRSVHee-aTPTPCVWRECFDAGRyrlkCGCVNGRCQW 209 Pyrobaculum calidifontis
WP_012939829  62 RCNSDEDCIVAGCSGQVCQSKFee-lTVTICEWLDCYGAEKfnvsCRCVDGRCQW 115 Archaeoglobus profundus
WP_012827076  79 ACTTDADCMTSGCSKEVCAAe----eVMTDCSVLEWPQGEAs--vCGCVENTCAW 127 Haliangium ochraceum
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