Conserved Protein Domain Family
near_uncomplex
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TIGR04222: near_uncomplex 
TIGR04222 domain
The majority of the proteins with a domain as described by this model have an extreme C-terminal sequence that is consists of extremely low-complexity sequence, rich in Ser or in Gly interspersed with Cys. That C-terminal region resembles ribosomal natural product precursors, although there is no evidence that C-terminal regions of these proteins undergo any modification or have any such function.
Links
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Statistics
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PSSM-Id: 275063
Aligned: 50 rows
Threshold Bit Score: 65.0348
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ZP_06216793   17 WYLLLAVVLVVGAIVYRRRMLA-GTA-----VTVNGDLGPQQVAYLNGGDQLAVWAALGGLRHSGAVGV---R----PDR 83  Micromonospora ...
ZP_01039977   15 FYCIMLVTCIFAGLWIPANLRP-E-------GRRGEVEDLEEVAVLTGGADRLSVAVLSSLFAKGALDVd-eR----KRL 81  Erythrobacter s...
ZP_06863081   16 LYAGLIVLGWLLALIVPAILRP-A-------GEPGRPRDFGQFAALASGKARYAEAVMADLLASGRLELe--G----KKF 81  Citromicrobium ...
ZP_06354578   21 FYYTIIITSRYLLILYKKKLHK-RQS-----ESLNVNEDPFFIAWLKDPTMGITNMVMGPLLDEGYITN---K----NNQ 87  Citrobacter you...
ZP_02000609   12 FYLSLSIITIVIGWLWLNTDDS-IRYp----LPELTELNSFEIAGLRDGNKGIIQTGLFNLWRYRLIIMkdrG----EQT 82  Beggiatoa sp. PS
ZP_02000578  347 IYLIIIFTMIIIDLLLTTSKNH-LTKdf--pIPSLTALNPYEIAALRNGRKGVIHTALFNLFRKELIMSekiA----ESN 419 Beggiatoa sp. PS
WP_011121581 226 LYGAAIVIGLVYLLVWFHITNG-WSSn----pSSPPKLGWGQLSILAGGKKRLLQTTLVALQKRGIVQC---Dq---HGF 294 Rhodopirellula ...
WP_012362805 231 FYLPVCIVALLLIVVLQQIEYRcRRRr---aQAFSSVLTAEEAAYLMGDESRAVQVATLSLVQAGAIDL---S----MGG 300 Burkholderia am...
WP_011350570 263 FYVPLCIAALLLIASLQWIEYR-HRAwgtraPESSPDLSAEEAAYLAGGGARMAQVAMLSLAHAGAIEL---RmskvHGA 338 Burkholderia lata
WP_012212501 226 FYIPACIVALLLIVGLQQVEYR-CRRrrvftREAVPDLSAEQLAYIAGEETRVVQVMTLSLIQAGAIDL---R----PAG 297 Burkholderia mu...

ZP_06216793   84 R----LTTGGP--LPAGA-TPLDQAVHHAAsRGL-----RTREL---AADEWVRRALDDLRDGLVRRGLALDQER----R 144 Micromonospora ...
ZP_01039977   82 A----VRQTGV--AE----NESERAILAKVg--------GFRPA---EAGRSIKAQAAAVETQLIRRGLMMDEGDr---W 137 Erythrobacter s...
ZP_06863081   82 H----VRDRQA--AT----GGAETRLMSLGd--------SFGWR---TFARAIDGGYQADRDALVDAGLLTGSGEa---L 137 Citromicrobium ...
ZP_06354578   88 Y----YQISKK--KKANT-TLYERLILDYFr-------kPNTVS---GISKIFTNKYEEHQKKAERMYLIYNDADk---R 147 Citrobacter you...
ZP_02000609   83 R----ILQKRM--FRQWPlGNLEEILYNFAiEPRkp-aeFFYHT---GLQSEINTFIQPINQNLEERHLKRTTYElrqaW 152 Beggiatoa sp. PS
ZP_02000578  420 V----VTVNNS--PTQQSeNAIEEAIYQFAaKKSpipkdFFTDL---SLRATLDKLMEPINQKLMQMHLKSDLELek-nY 489 Beggiatoa sp. PS
WP_011121581 295 T----MLDRGAlqAQHDD-DPVAVSAMKVTtDYLa---sSNAPQsfqRLLVAIHSTATNAESQMRESGLLRSTEQr---N 363 Rhodopirellula ...
WP_012362805 301 RmgarVRSVDP--TRGGA-YADECAWLAALpDGEa----SFGAF---RQLLARRVSDYANALRGRRGAWLWEAGEm---R 367 Burkholderia am...
WP_011350570 339 R----VRIGDP--RHAGA-YGADWEWLKRq-PGGe---tSCHAF---RQRLAWREADCAVA--LQRKGWLWAPGEm---R 399 Burkholderia lata
WP_012212501 298 RlgtrVTLVDP--ARAGA-YADEC---EWLaAQPg---gEVSFG---AFRQVLARRAAQYADAVRRREWLWAPGEm---R 362 Burkholderia mu...

ZP_06216793  145 RTLRRGALLVGAL-LAIGI---VRAVSGLLNDRPTG------WLLLSLFP-LGLAFVLLN--RVPW------RTRAATAA 205 Micromonospora ...
ZP_01039977  138 KLRALSAAPYAAL-LAIGL---YRQQAGAAIGEPTG------FLVALIII-TLVLGLFRF--AMGNp-----RTMAGNEV 199 Erythrobacter s...
ZP_06863081  138 PVRIVAALPMLAI-VLLGL---YRLQAGSAEGEPVG------ILVILIALgVVVIGWRLI--AGLR------RTREGERA 199 Citromicrobium ...
ZP_06354578  148 KIVKQHRRCLLSI-MALGL---YKLIIAINTGHTNIa-----YLTLTIFV----VVPVVF--ASRInmnavtLTPCGQKY 212 Citrobacter you...
ZP_02000609  153 QAFWVTTFFLVSIiSMAGIklyFEMAYGQQVDFLIT------FLIMMIFIaVIILMILIF--LIPNr-----STQLGRRY 219 Beggiatoa sp. PS
ZP_02000578  490 ESLFWKLWWIFII-YCTSY---TGFMIMMEIGTEPGnyislgFFVMNFFFvFIYLSFKNA--ILGNp----dNTQLGKRY 559 Beggiatoa sp. PS
WP_011121581 364 RFRVGGFSVAGIL-LAVGG---LRCLQGIQNDRPIG------FLVLEMIL-ATVGLAVAFhmAGHEr-----LTSLGKSV 427 Rhodopirellula ...
WP_012362805 368 AARMGSRAIALAV-LGTGA---AKLAVGLSRGRPVL------LLVISMAV-FAIAYRIVT--RRLTgfgrggLTVGGRTA 434 Burkholderia am...
WP_011350570 400 ATRMAARAILLLV-FGAGA---AKLAVGLTRGRPVL------LLMIVMTA-FMVAYHFMV--GRLPgfgrggMTRGGEAA 466 Burkholderia lata
WP_012212501 363 AARLAARAIVLIV-LGTGV---AKLAVGLSRGRPVL------LLGISMAA-FAIAYGIIA--ERLTgfgrggLSVGGRAT 429 Burkholderia mu...

ZP_06216793  206 LNDMRRRH-------AWLRPaagpaystYGATDVALGVALFGTATLW 245 Micromonospora aurantiaca ATCC 27029
ZP_01039977  200 VRSLEQNG-------SRLRRa-------PQANEAGYAVAIFGTGVLV 232 Erythrobacter sp. NAP1
ZP_06863081  200 LKEARQEH-------VGLKRa-------PTRDQMGLGVAIFGTAVLA 232 Citromicrobium bathyomarinum JL354
ZP_06354578  213 IRLYHDTL-------LNVTNkn--------lqQAWLSKVLTGGAAVa 244 Citrobacter youngae ATCC 29220
ZP_02000609  220 QKKLKKHF-------KWFKEea------ihETNPTILVAIFGVSAsd 253 Beggiatoa sp. PS
ZP_02000578  560 LEKLTEHFq-----wAKLNK--------SSGIAPILIVAIYGIKGLE 593 Beggiatoa sp. PS
WP_011121581 428 QERSQRSYpetglksAQQTD--------GGDLDELPSLACWGPAVAA 466 Rhodopirellula baltica
WP_012362805 435 LAEHQRA--------RRDEP--------DSPDAVLWATALFGAGALA 465 Burkholderia ambifaria
WP_011350570 467 LDAHRDQR-------RGDRA--------TPDGLLWtaalfgagalag 498 Burkholderia lata
WP_012212501 430 LDAHRND--------RHDER--------STPDDLLWATALFGAGALA 460 Burkholderia multivorans
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