Conserved Protein Domain Family
cas_csx17
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TIGR04113: cas_csx17 
CRISPR-associated protein Csx17, subtype Dpsyc
Members of this protein family are found exclusively in CRISPR-associated (cas) type I system gene clusters of the Dpsyc subtype. Markers for that type include a variant form of cas3 (model TIGR02621) and the GSU0054-like protein family (model TIGR02165). This family occurs in less than half of known Dpsyc clusters.
Links
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Statistics
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PSSM-Id: 274989
Aligned: 9 rows
Threshold Bit Score: 683.357
Created: 10-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ZP_01089597           7 IPLFGCRHDVLGHALKAIGILRAISacaalED-RDPDAEGWWslDDAAFMIRSSRYPDAASLv-kFFAEKYQPTPIIAAW 84   Blastop...
ZP_03725249           8 HLLPGCTPTPLASYLKALGIFRILS-----EQrPDTHPRAHW--QGNTFVLTTTNDANDANTlvdFFLNYYQPTPVLAPW 80   Diplosp...
ZP_03494117           5 IRLYGCRPVPMVGYLKAMAVLRLLA-----EQ-RDPNIRGYW--HQDVFCLQTELSPADLVD---FFLRMYQPTPIMAPW 73   Alicycl...
tigr:YS_M60-F11.238  10 LALPGLSPDSLGNYLASLGLLRVLS-----RN-----------------------------------------------W 37   Candida...
WP_011308049          5 IELKGCSTDNFSSYLKALGVFKIFS-----QQ-KDNNARAYW--KNNIFVINAEYDAAAMTN---FFLHEYAPSPLFRPW 73   Methano...
WP_013076618          2 ISLTGTAPQPLSHYLKALGVFRILA-----EQ-ADPEARGWW--EDERFHIETALHPQDVES---FFLAEYRPTPLVTPW 70   Kyrpidi...
WP_012638994         10 IVLRGCAPTPLAAYLKALGVLRLVC-----EQ-VDATAKGWW--QDECFMLRTRLDDNDLRR---FFIEDYRPTPMLSPW 78   Thioalk...
WP_013565398          6 HILKGCAPTPLANYLKALGILRLVG-----EQ-ADLKARGWW--EGERFCLLTTLSKEELER---FFLEDYAPTPLVAPW 74   Isospha...
WP_015752050          4 YTLPGCSTRPLGSYLKGLAVFRLVA-----EQ-KDPDVTAWW--DKGTFRVHTRLAPEELTS---FFCEQYTPTPIITPW 72   Desulfo...

ZP_01089597          85 NKS-----GGVtnkievailclsgdvsqFRADHEA-MLEAsglkktkklskvgalkfalsdaahlddlkkqatvaglvcs 158  Blastop...
ZP_03725249          81 NGG-----SGF-----------------FPKDNSK-ALDA---------------------------------------- 97   Diplosp...
ZP_03494117          74 NGG-----GGF-----------------IRGKNSE-PVDW---------------------------------------- 90   Alicycl...
tigr:YS_M60-F11.238  38 TRTriawlNGV-----------------LRVVGGPpTLDE---------------------------------------- 60   Candida...
WP_011308049         74 GGR-----SGF-----------------YKGSSEKsAREA---------------------------------------- 91   Methano...
WP_013076618         71 NGG-----SGF-----------------F--GRDE-ALRG---------------------------------------- 85   Kyrpidi...
WP_012638994         79 NGG-----SGF-----------------YRKGNET-AWST---------------------------------------- 95   Thioalk...
WP_013565398         75 NGG-----SGF-----------------FKKDNRK-AILA---------------------------------------- 91   Isospha...
WP_015752050         73 NGG-----SSF-----------------YPGDNTE-GLEA---------------------------------------- 89   Desulfo...

ZP_01089597         159 ykekrtrgkVT---TevtiaSTVEPLERFRREQSvplaelgfsvtknlSNDGqlkfstnssnrsnverLIADFNASLSDG 235  Blastop...
ZP_03725249          98 ---------IL---S-----STTPRFAAYRDTIA--------------AART----------------ALASLNLTEKPD 130  Diplosp...
ZP_03494117          91 ---------LR---N-----SSGARFRPYRDALQ--------------AVDR----------------VLAGAPLSDKPK 123  Alicycl...
tigr:YS_M60-F11.238  61 ---------LL---NelvriADSRDWTRYNKKDE--------------KKKE----------------WSDAQKESTKAK 98   Candida...
WP_011308049         92 ---------LR---Pli--dSKDSRFDSLRKVYD--------------AFQK----------------FSDSKGITEKPS 127  Methano...
WP_013076618         86 ---------IE---E-----SQTQRLHLYRTTIQ--------------TARA----------------ILKEFGLEKKPD 118  Kyrpidi...
WP_012638994         96 ---------LEkiiT-----TQAERWRPFRDTAE--------------VMAD----------------ALEHLKLTEKPA 131  Thioalk...
WP_013565398         92 ---------IR---S-----SSSERFEPFRQGIF--------------QAEQ----------------ILGD--LTVKPE 122  Isospha...
WP_015752050         90 ---------IV---Q-----TGDSRFRIYKEAIE--------------AVSSwpewgknvntvrelmaALQGMISSSNPG 138  Desulfo...

ZP_01089597         236 SRDagsdgntksqtsngplyaeisakesgtdgtlpkiermsmdpvllrclalarewvnelqtqgalrndSINILAQYRDN 315  Blastop...
ZP_03725249         131 SKEa-----------------------------------------------------------------KETLLLRCRNT 145  Diplosp...
ZP_03494117         124 DED------------------------------------------------------------------KVALLARLRAE 137  Alicycl...
tigr:YS_M60-F11.238  99 ---------------------------------------------------------------------SGTPLALWQAK 109  Candida...
WP_011308049        128 GDK------------------------------------------------------------------LVEFLEDLRAQ 141  Methano...
WP_013076618        119 NKD------------------------------------------------------------------KRPLVQACRNR 132  Kyrpidi...
WP_012638994        132 ELD------------------------------------------------------------------KRALLARLRAT 145  Thioalk...
WP_013565398        123 KKQ------------------------------------------------------------------KLAIQRKSVLA 136  Isospha...
WP_015752050        139 KKQdelftlqnnitnlaekvktteggdplgmrlvdlssrasekaevykqlwntakkartvytkdireqtKKIILPLCRSR 218  Desulfo...

ZP_01089597         316 LPTQVTEAFDAISICHLIR-RNDNPLFVNRGQQGRTDvFRMNWEHFIEF-----------RNAPDVFTQSSLFGERIttg 383  Blastop...
ZP_03725249         146 FSETALEWLDAAYVLTDEG-AKYPPLLGTGGNDGRLE-FTNNFMQRLSEvfdlaspdatpAKTSADFLRNALFDTPV--- 220  Diplosp...
ZP_03494117         138 LPDEAVEWLDAVAAITADR-LGFAPIYGTGGNDGNFE-FTNNFMQRLQElfqq---dgtpTQVAERLLRAALFDEPV--- 209  Alicycl...
tigr:YS_M60-F11.238 110 APESQLQLFAAHAVPHAH--VSFNPLLGSGGNAGRRD-FAAGWKKAVEAlan------atREKKKDALRSWLLGQPV--- 177  Candida...
WP_011308049        142 LPEDILEWLDTCYVLTGNN-RKYLPLLGTGGNEGSGN-YSSNYLQALTEvlv-----kkkEKESKQLLEHSLFSKHT--- 211  Methano...
WP_013076618        133 FPDAAVAWVDAAVVLTTGD-LGFPPLAGTGGNDGNLE-FTNNFMQRILNvmspk--tgqpTDTGGMWLRAALWGDAT--- 205  Kyrpidi...
WP_012638994        146 LDDEFLPWLDAAVLLTDDK-PDYPPLLGTGGNDGRLD-FTSNYMQRLLEmfdpv--tgkaQGDVGNKLESALFARPV--- 218  Thioalk...
WP_013565398        137 WRGEHRKWLDAAFVLDESRePIYPSLLGTGGNDGRLD-FTNNFMYHLVLlfleksstrssGNETRDLLCNALWSDLT--- 212  Isospha...
WP_015752050        219 LPDACLEWLDALCAIHADGeISYHQVLGSGGNDARLD-FGNNFMKKISAlll-----gsdQSASRKFLSASLWGTSV--- 289  Desulfo...

ZP_01089597         384 hTGSVKG-KGTPFFPDVIKSYNQG-LDWVTED-LpFCPLDYLLAVEGAFAMRGSVSKSLGARSQA----YAA-FPFVFEG 455  Blastop...
ZP_03725249         221 -TGLADN-PIGQFSPAASGGANAS-TGFDAKS-A-VNPWDFILAIEGAMLFASAAVKRLEGTTPG----QLA-YPFCVQA 290  Diplosp...
ZP_03494117         210 -NGLLNV-SIGQFQPGQNGGPNAG-PGFEASR-R-VNPWDFIFSLEGGILFSAAAARKFGRQYTD----FT--YPFTVRA 278  Alicycl...
tigr:YS_M60-F11.238 178 -TWMVEGlNAGSWFSQATKLYNSGqTPWREGQ-L--LPWAMVLACEGLVFFAGGASRRLGAKSAR----TVGaFPFITQP 249  Candida...
WP_011308049        212 -PKLSNL-SFGQLSPGAVAEANST-EGYRSTSkL-VNPWDVIFSIEGTTLFAGSASKRFGGSQGGfgsnFGA-FPFTVLP 286  Methano...
WP_013076618        206 -PELIRG-AIGQFSPGEAGGPNAR-SGFSGES-L-VNPWDYIFMLEGALVFASAAAKRLEKQSGS----VVS-APFTVYP 275  Kyrpidi...
WP_012638994        219 -PGMTAL-AIGQFSPGAAGGPNSS-TGFDSGA-Q-VNIWDYVLMLEGALLFAATATRRLESADPS----ALS-YPFTVRP 288  Thioalk...
WP_013565398        213 -RHLEIA-AIGQYQPGNAGGANSS-TGFDGGN-L-INSWDFVFAMEGALLFTSCATRRFDPQASS----QAS-APFAIRS 282  Isospha...
WP_015752050        290 -EGLPKT-KIGQFDPGRAGGYNQG-MGIEAKD-FtASPWDFILTIEGTLLLASSVGKRQGVSTGS----TLT-SPFTVRF 360  Desulfo...

ZP_01089597         456 PESM------------TDDQGDVTglgA---SLWFPIWTRPATFGELHSFILDSQARLP----K-------KDCRFSSDF 509  Blastop...
ZP_03725249         291 AGAGygs-------aaTADETDSR---C---EIWMPLWPAPALLPEIKTLFSEGRAWVG----R-------RLARNGLDF 346  Diplosp...
ZP_03494117         279 ASGGqga------msvTEEGQKAR---A---EMWLPLWRRPASLPELEQFVQEGRAHVR----SrrmsvgwRPVRTGVDF 342  Alicycl...
tigr:YS_M60-F11.238 250 IAAS------------AEKEADRLc--G---EVWTPLWSRPMSLAEVSMLFSRGRAELR----G-------RGALTPASF 301  Candida...
WP_011308049        287 SVAGtgnitfkdnfkdPNKKSDYK---TfdsEFWLPLWNRPTSYNEITYLFHEGRAQVG----R-------RKANNGLDF 352  Methano...
WP_013076618        276 TTVGhrs------taeLDGAQAAR---A---EMWMPLWRQPVSLPELLYIFREGRAQLSgdrvR-------RTAKNGVDF 336  Kyrpidi...
WP_012638994        289 SGGGsga-------vaLGDERPAR---A---EIWMPLWERPASLPELRVLLGEGRVTLN----G-------RLPRDGLDF 344  Thioalk...
WP_013565398        283 HAAGfa---------tPGFEKAQR---G---EQWMPLWRQPATLADLSAMLGEARIQLG----R-------QSAHRPIDA 336  Isospha...
WP_015752050        361 SPVGfts------nvyTEPEGPE----T---EIWMPLWNQPARYGEIKQLFSEGRCSIG----K-------RQAKSGLEF 416  Desulfo...

ZP_01089597         510 IRAIRSQGVDAGFTAFQEFRFKMKGAR----IPWAVT--GQFVTCSTTTsA--SLLNEflapVDasG--FLNQFrfrtpR 579  Blastop...
ZP_03725249         347 TLAVASLGVDRGIAEFQRFAFYVRNGL----AYFATPl-QRLAVSRNTIvT--DLIAT----CD--P--WLQRF-----F 406  Diplosp...
ZP_03494117         343 TRACAGLGIDRGIDSFQRYAFLERFGR----MYYAVAl-SRFHVRRRPE-A--DVLDD----LD--R--WLTQV-----Q 401  Alicycl...
tigr:YS_M60-F11.238 302 ATAIRKRGVDAGVSEFLRFTLRRTTSS----DTFEPRleARFLLGADARgDgkAVATA----LDctT--ALIEQ-----R 366  Candida...
WP_011308049        353 VRAISSLGVDRGIDAFVRYGRLKRQGSgknaNALAIPl-GTFKVRQQKN-V--NLIEE----LD--N--WLNVL-----R 415  Methano...
WP_013076618        337 ARACATLAVDRGIESFQRYAFLMRSGK----AYLAVPl-NRFIVRRQAY-A--ELLAE----LD--T--WLDLF-----A 395  Kyrpidi...
WP_012638994        345 ARAVAKLGTDRGVRAFQRYAFMMRSGK----AYLATPl-NRFHVHRNPK-A--DLIDQ----LE--RgdWLRRF-----R 405  Thioalk...
WP_013565398        337 ARAISRLGVARGVEAFVRYGYLERNGQ----SNLAVPl-GRIEVRYQPR-S--SLIED----LA--G--WMDRL-----Q 395  Isospha...
WP_015752050        417 SRAVGTLGVDRGITAFERYGFLKRRGE----NKVALPa-GKIAVRFKPS-L--ELVNE----LD--P--LLSKL-----D 475  Desulfo...

ZP_01089597         580 EVKRDRKP---D---LHPYRAPILEAIETAAVEPSST-K---IIDVLSKLATLNTQLAQSKALREkvsggRVTFVP-PLR 648  Blastop...
ZP_03725249         407 SKAKTDTAp-sS---IRRAARRLENAILAQATAAQTN-NsgvTQELLIALGECERALATSEKWRA-----DSYIPPiPPL 476  Diplosp...
ZP_03494117         402 ALPSMKEPp-lS---ALSALRRVEDAVFDLCQHGGAH-R---VRELIVAVAQMDRVVSLRPNLRE-------RVEPlVLE 466  Alicycl...
tigr:YS_M60-F11.238 367 GFPKDGKP-------FAGLRGPIESALLEVASEPHRP-Ea--GIALLDAVVRALDRIDRNRSFREg----RVHWKPlPL- 431  Candida...
WP_011308049        416 DKCSSKES---VaarYSSSLRSIEEAIFSFSKHGNIS-D---FQNLLIELGKAERSFASAGANRP--------IRPlNDL 480  Methano...
WP_013076618        396 RVENTSHA-------FQSALHRIREAEFLYCQYGGAR-R---MQDVLVALGRAEQLLARVPSARQ-----K--VPPlVLR 457  Kyrpidi...
WP_012638994        406 RAARSTHA---Pa-rLQGLAHRLDDALFDLVRVADPR-R---VQEVLKVLGEVQFYLALSPSLRE------Q-VRPvPRL 470  Thioalk...
WP_013565398        396 SRSRDGKA---Ta-rLIHAERRLADAVFAALTHDHTSdR---WQAILLAAVEVETLQATGTALE---------VGPiPRL 459  Isospha...
WP_015752050        476 QFLRAFKKpptS---FLQARQKIDQNIFNCTLQPDPV-Q---FLKIVRSLGQMEKRIALRDRDKD-----PKLPQPlFGL 543  Desulfo...

ZP_01089597         649 CDDWs--sALQDLQVDPEFEIAWALASICGhekqpdGTSSQVEPFLGSLIPLRRl--gEKWVLPEMP----Dpp------ 714  Blastop...
ZP_03725249         477 PRAW----VLAADTGSREYRLAASLASLHLya---kNTFWPIRRHLEPVKLHHGenawAAWDDSALN----D-------- 537  Diplosp...
ZP_03494117         467 SKAWieqaWPKDAREQAEFALGLAIGTMQD------VDGISHRQYFAPVLVGERr--tCQWVSNEEM----Psa------ 528  Alicycl...
tigr:YS_M60-F11.238 432 --EWlp-sLFADEQPGVEARLALSLVSAF-------PPTLPFAAFRFGVQWTREqngkYEYDWTTEP----Eqfehskva 497  Candida...
WP_011308049        481 SPSW----INACDDESVEFRIACAVASIYD------KKIGSIRRQLEPSEINNK----GRLKWSETR----S-------- 534  Methano...
WP_013076618        458 NPGW----WRASDDGSPEFRIAGAFVSVYP------GSAGSIRSFLSPVDPGHP----GRWGPETDP----P-------- 511  Kyrpidi...
WP_012638994        471 DAHW----VEAARDDSHEFRVAAALAGL--------DDGLPMGVHLAPIDPVKR----NVWAPESRL------------- 521  Thioalk...
WP_013565398        460 RPEW----VAAVDDGSAEVRLALALGSAAAeyd-krKPVDSVRYHLLPLEPKNA----GRFQLADKRlvndP-------- 522  Isospha...
WP_015752050        544 SPQW----IIKSDDGSPETRIAAALASIHSt-----GKVGPIRSNMAGVRAQAP------WHWEDRD----S-------- 596  Desulfo...

ZP_01089597         715 spQAVWTGIDLARDLSSVLARRVLDSAK-----------------DFRPAIVgTC-----TAQLTSILRFLQGELDDRRI 772  Blastop...
ZP_03725249         538 --VVASVNVPITDTLCAIMRRRLLLAKTgs--------------hDTWPEFS-KL-----SAWPVDIAAFIEGLTDDDRL 595  Diplosp...
ZP_03494117         529 rvRFAFDSPDLVRCLLRLAERRLLDEERvrqraggs-qedksednQDKSKIGfHCrhdrfAARLEHLVPFWFGETRDARI 607  Alicycl...
tigr:YS_M60-F11.238 498 paHWVWGPGELARVLGSVLSRRLLEEAArdg------------tnTERPQGRaPL-----PATTSQIRQWLTGELDESLF 560  Candida...
WP_011308049        535 --SVVWSNTDLCSNMKAILQRRILEEKMkg--------------sNFTPIGG-KV-----AVSLSDIGRFIRGEVNDKKI 592  Methano...
WP_013076618        512 --RVVWKHTDVAANMAAVLRRRLLETHRsvgggenagsaaistdeFDKPTAG-PR-----TVPLSLIGQFLKDPGWDARV 583  Kyrpidi...
WP_012638994        522 ---AVWGQGNLSDNLAQVLQRRLLTASRtd--------------lNDKPLSG-RC-----PADEGAVAAFLAGDADERRI 578  Thioalk...
WP_013565398        523 --RVVATGRDPLRDLAAIVERRLIESAQkg-------------qrRSRLVAAsGC-----EARLNDLAQFLRGELDLNRL 582  Isospha...
WP_015752050        597 --QQHWFGSDLTEKLGNVLTYRLMDAERks--------------vSNIPFMG-NL-----ELSPYDVMPFLHQETKDDLL 654  Desulfo...

ZP_01089597         773 ARLVEA-LSLIDWRYSAAHTVVNKSFSDEEVDWDSvPIAYAAARSLIEVAcekrrt--------eaaeieDRSGPRTKVQ 843  Blastop...
ZP_03725249         596 AQLLWG-LCLVDFSEDSNRTNMPARPDGTERDITP-PAFYAQLKLCFAAR--------------------LPDSRAVPVT 653  Diplosp...
ZP_03494117         608 LDYAWA-FSAYQGDAPNVRHDEAMP--------AWiPYLYALLRLVFTSErdlrqalrnvsrrglgqppsVEDRFSLPVP 678  Alicycl...
tigr:YS_M60-F11.238 561 AAWLSR-LALFDWRIIPKKVCMLIPKEDNTPRADGaLALLGLFQPLIDWQplivrdla-----pndllskETGARTTEAA 634  Candida...
WP_011308049        593 SDLIWG-LSIIKWKYYNKERHGVDWNNGIDV---MiPRAYAFLKLIFIPGnlifenq------rweisydEKKGIHLPSL 662  Methano...
WP_013076618        584 ADLIWGlLPLYRSVASDEVRSSGSPGFRFHRSMTPlPWAYILARLISAPNaql--------------qrvFPGAMPLPVP 649  Kyrpidi...
WP_012638994        579 AELMAG-LACARLPARLPLRQRGASE------ASSlPMIYALLKPLFVPDaqlr------------eagvLTPDGCLPLP 639  Thioalk...
WP_013565398        583 FGLARA-FMAIRWDRWSKAFQPKVNQKNHHPEECWlALRLC----CLPWE--------------------ITENLDIPAD 637  Isospha...
WP_015752050        655 EDLLWG-FTLINWRKSGIQSIRNKWEKPTQQ--TVlSRTWCLLKLLHHPN--------------------KIKGHSFKRE 711  Desulfo...

ZP_01089597         844 RTVALLS---RQEPrlA--ALATTDALRRLAIVGVPN--------PygeesrrekpkLSGRDVVLVDGslgidvdlaRRL 910  Blastop...
ZP_03725249         654 PDIFNLA---ANGD--G--ARASAQALRRLHGSSVPV--------L-----------HINIPLDGAAS---------RRA 698  Diplosp...
ZP_03494117         679 REVLALVgtdRSAD--A--VRARQVLERRFVASGLST--------R-----------HRGTDTFGFSP---------RRM 726  Alicycl...
tigr:YS_M60-F11.238 635 RALVMLI---RAGN--I--DAAVRLAGSRYAMAGARL--------A-----------SFNVPFATHDP---------DRL 679  Candida...
WP_011308049        663 PEVLRVI---DT-Q--Q--DKAFELVTRRLKSSGLTPlgvrrnkvA-----------APDFNVNTEDR---------ERI 714  Methano...
WP_013076618        650 DRMLSLL---AAGE--L--NRAAGVAEQRLRGSGFSS--------PffrkgslprvnHWTAGNPQRTG---------TRI 705  Kyrpidi...
WP_012638994        640 PALPRLL---RAGP--AgvGRAVDLARRRRRASGLAD--------A-----------GWRLTPPYPDG---------GRL 686  Thioalk...
WP_013565398        638 ERIVRLL---LAGD--A--SRAIEIARQRLRSKGIRP--------P-----------IYAGMTDPQTA---------RRW 682  Isospha...
WP_015752050        712 KSISHLL---QAHR--V--DEACNKATQRLRISNLHP--------------------FPIYFEEELEP---------QRL 755  Desulfo...

ZP_01089597         911 AAAVLIPLDRRDRWSLFRSITLPQ 934  Blastopirellula marina DSM 3645
ZP_03725249         699 AAALLFPLWDSQLAATCFPVALAL 722  Diplosphaera colitermitum TAV2
ZP_03494117         727 LASAIVPIQSRSLEILASRLWPKQ 750  Alicyclobacillus acidocaldarius LAA1
tigr:YS_M60-F11.238 680 AAALLFPLSAYDRTTLFTRWLRPR 703  Candidatus Chloracidobacterium thermophilum
WP_011308049        715 VASLLIPIWQYNR--LFELVLQPP 736  Methanosarcina barkeri
WP_013076618        706 LAALALPIADRDLRQLAQLAGLTS 729  Kyrpidia tusciae
WP_012638994        687 LAALMIPVEIRVIKGFIKRLADHK 710  Thioalkalivibrio sulfidophilus
WP_013565398        683 AAALVFPIHRRTAQNIVGYLSPTM 706  Isosphaera pallida
WP_015752050        756 LASLMLPVKDQHILENLVLERTTI 779  Desulfohalobium retbaense
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