3SWJ,3GAS


Conserved Protein Domain Family
heme_ox_HugZ
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TIGR04109: heme_ox_HugZ 
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heme oxygenase, HugZ family
Members of this protein family are HugZ, a class of heme oxygenase that belongs to the PPOX family (pfam01243) and lacks homology to the HmuO family (pfam01126). Characterized members of this family include HP0318 from Helicobacter pylori and CJ1613c from Campylobacter jejuni. This enzyme releases iron during the conversion of heme to biliverdin.
Links
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Statistics
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PSSM-Id: 200360
Aligned: 8 rows
Threshold Bit Score: 331.311
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3SWJ_A         5 SIISHMNDHHKSNLVDLCKKFGGIEQVQDVFLKSVDFNGLDLVYNdKENLRVEFPKKA-DENT-IKDTIISLCMSAKSEQ 82  Campylobacter j...
WP_002862255   5 SIISHMNDHHKSNLVDLCKKFGGIEQVQDVFLKSVDFNGLDLVYNdKENLRVEFPKKA-DENT-IKDTIISLCMSAKSEQ 82  Campylobacter j...
WP_000934548   4 RIIEHMNAHHVEDMKGLLKKFGQVHHAENVAFKSVDPQGIVIGYNhNQTLRIEFNHEVkDPKD-YKNAIIELCQSVEKTH 82  Helicobacter py...
WP_005693201   5 RIITHMNDHHQDDMAVLCKKFGGEKEITDVTLVNVDFAGLDFKYNgGKTLRVEFPQQA-DAGS-IKQVIINLCVENKPVA 82  Haemophilus inf...
WP_002847781   6 KAIEHMNSDHMDTLIMLCKHFGAVQNPTNVRLDSIDEDGMDIACD-QLLVRVAFLKKAeQNGEgFKTAIIDLMSSLDIKE 84  Campylobacter f...
WP_006807059   4 RILNHMNEDHNDVLALYVRYFNKRDDVKEARLIDVNEEEMTLRVNgNEDVKVKFTKRTeFEH--MHLEMVKMAKIARKEL 81  Leptotrichia go...
WP_011992776   6 RAIDHMNADHSDIVCVFCEVFGKFENPTNVLMTAINEDGMEISCD-QGKIFVPFLQKAnVNGEgFRNEIIALYSKIKSEQ 84  Campylobacter c...
3GAS_A         4 RIIEHXNAHHVEDXKGLLKKFGQVHHAENVAFKSVDSQGIVIGYNnNQTLRIEFNHEVkDPKD-YKNATIELCQSVEKTH 82  Helicobacter py...

3SWJ_A        83 NFSG---------------------------------VEKELNEFMLSFNSVALATLNANGEVVCSYAPFVSTQWGNYIY 129 Campylobacter j...
WP_002862255  83 NFSG---------------------------------VEKELNEFMLSFNSVALATLNANGEVVCSYAPFVSTQWGNYIY 129 Campylobacter j...
WP_000934548  83 DLKG---------------------------------VEEEVKAFKESFDSVCLATLHPNGHVVCSYAPLMSDGKQYYIY 129 Helicobacter py...
WP_005693201  83 NYDR---------------------------------IKAKIDEFRQEFKSCVLSTLDKDGLPMASYAPIIFFDGKYYIY 129 Haemophilus inf...
WP_002847781  85 GIAA---------------------------------VSKDMIDFIDSFNSVLISSLNGD-HCVCSYAPVVRDNNDFYIL 130 Campylobacter f...
WP_006807059  82 GIPAperykdk-------------------shlqeeeIKIEINDFIRKFKSVILGTVTEDGEPNVTYAPFLRFRGDDYIF 142 Leptotrichia go...
WP_011992776  85 RAAAkggahphavghghgagahphgsghpggekkeskAQESMMALVDSLKSLIISSVDANGDCVSSYAPFVKEGEDIFFC 164 Campylobacter c...
3GAS_A        83 DLKG---------------------------------VEEEVKAFKEGFDSVCLATLHPNGHVVCSYAPLXSDGKQYYIY 129 Helicobacter py...

3SWJ_A       130 ISEVSEHFNNIKVNPNNIEIMFLEDESKAASVILRKRLRYRVNASFLER-GERFDQIYDEFEKQTGGEGGIKTIRKMLDF 208 Campylobacter j...
WP_002862255 130 ISEVSEHFNNIKVNPNNIEIMFLEDESKAASVILRKRLRYRVNASFLER-GERFDQIYDEFEKQTGGEGGIKTIRKMLDF 208 Campylobacter j...
WP_000934548 130 VSEVAEHFAGLKNNPHNVEVMFLEDESKAKSAILRKRLRYKTNARFIER-GAEFDKAFDSFIEKTGGAGGIKTIRAMQDF 208 Helicobacter py...
WP_005693201 130 ISAIAEHYENLKRNPNQVEVMFLEDENKAKSIIVRTRLRYKASARFIPReDPIVEKVLDKLAETMNDVGGIKTIREFTDF 209 Haemophilus inf...
WP_002847781 131 ISEVSEHFKSIKENSDKISIMFLEDESKAKTVFARKRASFRSKAIFLDD---KKESLFSKFESKFKSESAIKMIKNMSDF 207 Campylobacter f...
WP_006807059 143 ISTTGDHFDNLKNNG-KLEVLFIEDEEKSKMISARTRVRYKAVAEFLER-NAQFEEIMDEFQQKDSL---IKMTRTMKDF 217 Leptotrichia go...
WP_011992776 165 VSSVSQHYHTIKANPSKVSVMFIEDEKDARTILARHRLSSKCEINFVEN-EAKRDEIFDKLQAKNPNDGSFEDIKGMKDF 243 Campylobacter c...
3GAS_A       130 VSEVAEHFAGLKNNPHNVEVXFLEDESKAKSAILRKRLRYKTNTRFIER-GAEFDKAFDSFIEKTGGAGGIKTIRAXQDF 208 Helicobacter py...

3SWJ_A       209 HLVKLEFKKGRFVKGFGQAYDI-E-NGNVTHVGASGNPHK 246 Campylobacter jejuni subsp. jejuni S3
WP_002862255 209 HLVKLEFKKGRFVKGFGQAYDI-E-NGNVTHVGASGNPHK 246 Campylobacter jejuni
WP_000934548 209 HLIALDFKEGRFVKGFGQAYDI-L-GDKIAYVGDKGNPHN 246 Helicobacter pylori
WP_005693201 210 DLVELTFGTGRFVRGFGQAYLI-DaNGEISHIGVKGNPHE 248 Haemophilus influenzae
WP_002847781 208 HIIKIEINKGRFVKGFGAAYDT-D-GFEIIQRAHGANPHN 245 Campylobacter fetus
WP_006807059 218 YLVKLKLIKGRYIKGIGKAYDIaE-NGEIKHITQDGHVYG 256 Leptotrichia goodfellowii
WP_011992776 244 YIVKAVLKKGRYVKGFGAAYDV-D-GLEITKGLQDSDPHT 281 Campylobacter curvus
3GAS_A       209 HLIALDFKEGRFVKGFGQAYDI-L-GDKIAYVGDKGNPHN 246 Helicobacter pylori NCTC 11639
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