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alternate signal-mediated exported protein, CPF_0494 family Members of this largely Clostridial protein family contain the cognate signal peptide domain, modeled by TIGR04088, for the variant SipW form of the signal peptidase I family. The remainder of this protein, however, differs from families such as Peptidase_M73 (pfam12389) and YqxM (TIGR04087) that share the same signal peptide domain. Some additional homologs to this family lack full-length homology and are excluded by the trusted cutoff as set. The two known targets for export by the SipW signal peptidase in Bacillus subtilis act in producing biofilm matrix material. Members include CPF_0494, adjacent to SipW homolog CPF_0493. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",