Conserved Protein Domain Family
rSAM_pep_methan

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TIGR04083: rSAM_pep_methan 
putative peptide-modifying radical SAM enzyme, Mhun_1560 family
Members of this family are radical SAM enzymes, homologous to a variety of other peptide-modifying radical SAM, and found primarily in methanogenic archaea.
Statistics
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PSSM-Id: 274966
Aligned: 10 rows
Threshold Bit Score: 684.149
Created: 10-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012106119   6 HVMIIPTLGCPSKCKYCWSSEEGSPIMSVETVHEIVVWLQDIP-RDRVTFTFHGGEPLLAGADFYRQALPLLADGLAQMH 84  Methanoregula b...
WP_011843737   6 HVMIIPTLGCPSKCHYCWSSDERSPVMSIKTVREIAEWLKDYQ-SNQVTITFHGGEPLLAGADFYRQALPTLSEGLAHLE 84  Methanoculleus ...
WP_012618707   6 HVMIIPTLGCPSRCHYCWSSDETSPVMKIETVRDVVAWLNDFR-DDRVTFTFHGGEPLLAGADFYRQALPLLSEGLSHLN 84  Methanosphaerul...
WP_011023249   4 HVMLIPTLGCPANCNYCWSSEEKSPIMSIETIKEVVEWLKVFR-QDSVTFTFHGGEPLLAGVDFYREALPLLAEGLSPRN 82  Methanosarcina ...
WP_012037366   4 HVMIIPTLGCPSKCHYCWSSDVNSPVMSLDTVKDIVAWLKEFR-DDNVTFTFHGGEPLLAGADFYKKALPLLQKGLKDRH 82  Methanocella ar...
WP_011448556   6 HIMLIPTLGCPSNCKYCWSSEEGSPVMNIQVVKDVVSWLSDFR-DDPVTITFHGGEPLLAGPDFYRQALPLLAQGLAKNK 84  Methanospirillu...
WP_012900589   4 HVMLIPTLGCPSKCSYCWSSDPDSPKMSVDTIKEVVEWLKEFRpGEAVTFTFHGGEPLLAGADFYNKSLALLSKSLKDRK 83  Methanocella pa...
WP_011695656   8 HVMIIPTLGCPSKCSYCWSSEEGSPVMSIDTVKEIVEWLKLFR-DDPVTFTFHGGEPLLAGVEFYRKALPLLADGLSHLT 86  Methanosaeta th...
WP_011833892   6 HVMIIPTLGCPGRCKYCWSSDETSPRMTLDTIDDIVTWLKPLE-DQRVTFTFHGGEPLLAGAEFYRQAFKKITEGLPHLS 84  Methanocorpuscu...
WP_011954629   4 HVMIIPTLGCQCNCKYCWGSESTKEMMDISVIDDIITWLKDFR-DDKVHFTFHGGEPLLAGYDFYAEALEKLSK--IDNL 80  Methanobrevibac...
WP_012106119  85 PEFAMQTNLWRMTPEIADALAAYRVPIGSSIDGPEAITDSQRGDGYYQKTMKGYGIAKAHGLDVRFICTFTNKSVKNKEE 164 Methanoregula b...
WP_011843737  85 PTFALQSNLWLLTPEMARIFAEYNIPIGSSIDGPEEINDTQRGKGYYQKTMRGYEIAKANGLEVRFICTFTCRSVEGKEE 164 Methanoculleus ...
WP_012618707  85 PEFAMQTNLWLMTPEIAEILAAYHVPIGSSIDGPEEINDSQRGRGYYEKTMKGYEIARAHGLLVRFICTFTNQSVRLREE 164 Methanosphaerul...
WP_011023249  83 IAFAIQTNLWKLTPEIAEIFARYDVPIGSSLDGPQELNDLQRGKGYYEKTMKGYEIAKAHGLTVRFITTFTSHSVKFRED 162 Methanosarcina ...
WP_012037366  83 VAFAMQTNLWLMTPEIARVLAKYNIPIGSSLDGPEDVNDFQRGKGYYQKTMKGYTIARENGLDVKFICTFTSHSIKHKDE 162 Methanocella ar...
WP_011448556  85 PSFAIQTNLWRMTPELADIFAEYHIPIGSSIDGPEDITDYQRGDGYFQKTMAGYRVAREHGLNIRFICTFTGYSEKQRES 164 Methanospirillu...
WP_012900589  84 IAFAMQTNLWLMTPEIAKVLAKYNIPIGSSLDGPKALNDMQRSEGYYDRTMKGYRIAKENGLDVKFICTFTSYSVKQKEK 163 Methanocella pa...
WP_011695656  87 PSFALQTNLWRLTPELAEVLKEYDVPIGSSLDGPKEINDLQRSEGYYDRTMRGYGIARDHGLSVQFICTFTSHSIKYKQE 166 Methanosaeta th...
WP_011833892  85 PEFAIQTNLWLMDDELAEIFAEYQVPIGSSIDGPQELTNYQRGDEYFERCLAGYKIAVDHGLLVRFICTFTNSSVKQKEA 164 Methanocorpuscu...
WP_011954629  81 EGFSLQSNIWLLSDELIDLFLKYNVAVSTSIDGPEEINDYQRAEGYFKKTIGRYERAKEKGLNINFVLTVTQYSKDYSDE 160 Methanobrevibac...
WP_012106119 165 IFQFFLDKGFTLKLHPALPSIRSENPKEWALEPSEYGELLVYLLDQALDHMGEIEVMNINDLCRCVFVRRGSVCTYVDCM 244 Methanoregula b...
WP_011843737 165 IFNFFLENGFPLKLHPALPSLRSEDPKEWALEPEAYGELLVYLLDKYLENLSKIEVMNINDLCRCIFTRHGTVCTFVDCM 244 Methanoculleus ...
WP_012618707 165 IFDHFLQHGFTLKLHPALPSLKSDDPGQWALDPEEYGELLVYLLDRAIEKRDEIEVMNINDLCRCVFTRRGSVCTYVDCM 244 Methanosphaerul...
WP_011023249 163 IFNFYLEKGLTLKLHPCLPSLKGDNPEKWALDPEKYGELLIYLLDKYLENMGKIEVMNIDQLCKCVFTGRGTVCTYVDCM 242 Methanosarcina ...
WP_012037366 163 IIQFFMDNGWNLKLHPALPSIKGDDPGKWALDAGEYGELLVYLLDTYLENWGRFEVMNIDHLCKCVFKRHGVVCTFVDCM 242 Methanocella ar...
WP_011448556 165 IVQFFIDQGFTMKLHPALPSLRSESPNEWALAPEKFGDLLVYLLDQSLDHYHEIDIMNINDLVRCVFTRRGNVCTFADCM 244 Methanospirillu...
WP_012900589 164 IFNYFLKNDLTLKLHPALPSLRSNKPGEWALDPEEYGELLVYLLDKYLENMGKIEVMNIDHLCKCIFTGHGTVCTYVDCM 243 Methanocella pa...
WP_011695656 167 IFDFFMSNGLTLKLHPALPSLRSDEPERWALDPSEYGELLVYLLDRYLENMDRIEVRNINDLCRCVFSGRGTVCTFVDCM 246 Methanosaeta th...
WP_011833892 165 IVNFFKEQGWVMKLHPALPSLKGENPNAWTLAPEEYGELLVFLLDEAIEHADDLEIMNINDLCRCVFTRAGSVCTYADCM 244 Methanocorpuscu...
WP_011954629 161 LYEFFKSHGMNLKIHAALPSLRGDNADPWALDQEEHGKLLIDWLDKYLYDLDKFSVMDLDHIAKSTFRRRGTLCTFADCI 240 Methanobrevibac...
WP_012106119 245 GSTFAIGPDGSIYPCYRFVGMPEYVMGNVADRPSLETLMESPAGKLMLAFKDYVDTACAECKHIKYCRGGCPYNAMAPTP 324 Methanoregula b...
WP_011843737 245 GTTLAFGPDGSIYPCYRFVGMPEYAMGNVYDRPTAEDLAQSDAWKLMHAFKEFVDRECAGCPHIKYCRGGCPYNAITPTD 324 Methanoculleus ...
WP_012618707 245 GNTFAVGPDGSIYPCYRFVGMPEYILGHVSDHPTMDDLNGSPAGKRMFEYRDYVDTACGGCSHIQYCRGGCPYNALAATP 324 Methanosphaerul...
WP_011023249 243 GDTFAVGPDGGIYPCYRFVGMPEYVMGNVYDRPTMADLAQSDAWKLMHKYKEFVDSECGKCSHIKYCRGGCPYNAIVPTD 322 Methanosarcina ...
WP_012037366 243 GDTFAVGPDGSIYPCYRFIGMPKFVMGNVKDKPTMEDLMSSKAGKLMEKFKKFVDKNCKECAHIRYCRGGCPYNAIVPTD 322 Methanocella ar...
WP_011448556 245 GNTYAIGPDGSIYPCYRFVGMDEYVMGNVRDRPTQKDLDESKPGRLMNDFKAYVDTHCSSCSHNKYCRGGCPYNAIAPSG 324 Methanospirillu...
WP_012900589 244 GDTFAIGPDGSIYPCYRYVGMPTYVMGNVHDHPTMEDLMGSKAGKLMLRYKKYVDKHCKDCTHINYCRGGCPYNAMAPYD 323 Methanocella pa...
WP_011695656 247 DNTFAVGPDGSIYPCYRFVGMPDYVMGDVRDHPSMDDLKRSEAWRRMNRFRECVEVHCRKCRHLRYCRGGCPYNAISHTD 326 Methanosaeta th...
WP_011833892 245 GTTYAVGPDGEIYPCYRFIGMPEWVMGHVRNAPSIESLMESHAGKRMLAFKEFVDTACKDCAHITYCRGGCPYNAIAPTG 324 Methanocorpuscu...
WP_011954629 241 GTTLAVGADGSIYPCYRFVGMDEYILGNVKANPSFDKLKESDAWAKLQEFREYVDENCAKCRYVKYCEGGCPYNAIVASK 320 Methanobrevibac...
WP_012106119 325 GRIEGVDPHCTAYTRIFDEIGDRLNREMF-AAPPMEMGGFGMPsvqkPAK-KEKPGVMTLMRR 385 Methanoregula boonei
WP_011843737 325 GEIQGVDPHCIAYKRIFDEITNRLNEEMF-GSGDTEMEEFGSP----LQR-TAKPGIMAILRA 381 Methanoculleus marisnigri
WP_012618707 325 GEISGVDPHCVAYKRIFTEINDRLNREMY-ESP-MIGAGSGSRs---ARR-KEKPGVTALMRS 381 Methanosphaerula palustris
WP_011023249 323 GEIKAVDPHCVAYKMIFDEITDRVNQEMF-GSAGS-MDMFLPQ----TMK-PSRPGIMSLMLK 378 Methanosarcina acetivorans
WP_012037366 323 GKIKAVDPHCVAYKRIFDEIKERQNRDLLaGTSGLEGAIMGFD----PMRmAAKPGVMAIMLK 381 Methanocella arvoryzae
WP_011448556 325 GEITGVDPHCIAYKRIFDEITDRMNTEMF-EAPPM-FGGFGPGqtgtGMG-KTKPGIMALMQK 384 Methanospirillum hungatei
WP_012900589 324 GKIKGVDPHCIAYKRIFDEIIDRMNSDMFgGSSSLESASFGFP----PQQ-SSKQGIMAIMLK 381 Methanocella paludicola
WP_011695656 327 GEIRGVDPYCIAYKRIFDEITERFNREM--------LSSFGLQ--------SSKPGIIALIRK 373 Methanosaeta thermophila
WP_011833892 325 GSLEGVDPHCTAYKRIFDEITTRLNEEMN-AAPVSRVS----R----VKR-QKKPSVTRLIQK 377 Methanocorpusculum labreanum
WP_011954629 321 TP-KAVDPQCKAYKMIFGEVSKRLNKEFA-KNAFGGLNGPGIK-----KE-NEAFSIMDLMMK 375 Methanobrevibacter smithii
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