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exported signaling peptide, YydF/SAG_2028 family This family describes a rare family of small proteins, about 50 residues in length, that includes YydF from Bacillus subtilis and SAG_2028 from Streptococcus agalactiae 2603V/R. Mutational analysis and genomic context show that members of this family likely are modified by a (variably present) radical SAM enzyme, are exported by an ABC transporter, and serve as signaling peptide. The member from Bacillus subtilis induces the LiaRS two-component system. [Regulatory functions, Protein interactions] |
Jiyao W et al.(2023). "The conserved domain database in 2023.",