Conserved Protein Domain Family
rSAM_paired_1
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TIGR03978: rSAM_paired_1 
His-Xaa-Ser system radical SAM maturase HxsB
This model describes the upstream member, HxsB, of a pair of uncharacterized radical SAM proteins, regularly found in the context of a small protein with four or more repeats of the tripeptide His-Xaa-Ser (HXS). This enzyme appears to be part of a peptide modification system.
Links
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Statistics
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PSSM-Id: 274896
Aligned: 18 rows
Threshold Bit Score: 591.154
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDM20916       5 LLPFRFERFDENKYLLTNEVGEYIFLSNEDFQCFVDGKLDEHSELFYDLASKQIATTDKTEDVV-R-MLATKFRTKKSIL 82  Bacteroides cac...
EDM58511       3 VLPFNFEFLDSDIALLTNQAGFHAYLSRMELNSLIDKNSTDDAVIDELLERKLFICDDEYKSASvG-SLASGMSKRLMSA 81  Vibrio parahaem...
EDM81026      16 QAFFRWRQIGDDAILVTNLEGNWLILTEDEFTAYARGEVAPDSDLHGRLDEKNFLRASYDV----Q-AASERVKARRYFV 90  Plesiocystis pa...
EDU59447       3 LLPFNFEKISEEDFFISNLAGYSTTLKSENFFELVNEHATSNELLNKELIEKLFISNNVLLAE--K-MLSSALGKKITNE 79  Providencia stu...
EEC93040       4 LNHFNFRALDDGDFLITNDYGRALFVSPEEFQRFLRQDFDGAEALYQRLHRAHFVLDPMEIYA--D-SMTDELREMKQYL 80  Mitsuokella mul...
EED59418       3 LNYFNFKSFEDE-ILLTNDLGEHIFLKNEEFHQLISKSVQQESDLEKKLLEKYMIYDETNLEFT-N-KNRYEMQYLKGHL 79  Blautia hanseni...
WP_011899284  20 LFPFNFERLSQDEVLIVNAVGEFSFIQDRELQELVAGELPTDTELYQELKRKSFLAGSEDSYAL-R-CLSAKYRQRKSFL 97  Aeromonas salmo...
WP_011790688  16 LLPFRFERVNDDRFLLINEVGEHCYLNCADLNNLVNGYLTTSGKTFQNLESKSFVYSENNNFAL-R-AFSAKYRARKSFL 93  Shewanella sp. ...
WP_012078870   7 PLPFLTREISDELMIAISESGDHIFTSVDEVRQIRKHPSSLSHERQAFLRARFFIKSVDQSPGM-RrLLISRRAARRTTT 85  Janthinobacteri...
WP_015959892   3 LMPFNFDRMPDDRVFISNLAGFHHFLGEKEFLDLVNGHISQEQSSSLE--SKLFISGDDNSSVTpY-AYSSAFAKRLLNE 79  Enterobacter sp...

EDM20916      83 RDFTSLHMIVPTLRCNSSCIYCQVARKNMDDHSADMTKKTAKNVVKTIFQSPSPFIKIEFQGGDPSTDFDMVKYIIEEAE 162 Bacteroides cac...
EDM58511      82 LNFNPIFMIVPTLRCDHTCHYCQVSRASVKASNYDLEPDLIPLLLQRIRSLGNAPYKLEIQGGEPLLRFDLVQKIYQEAV 161 Vibrio parahaem...
EDM81026      91 HGGPLLHVMVVTLRCNETCVYCHASRANMDAVHTDMTPEIARKAVDVALSSTNGFVTIEFQGGEPLVNFPVVKEIIEYAT 170 Plesiocystis pa...
EDU59447      80 IKFSPIFMIVPTLRCDHTCKYCQVSRASLSAKNFDLKEEKIPKIISLIKKLSSKPYKIEIQGGEPLLRFDLIKKIYQEAV 159 Providencia stu...
EEC93040      81 CYGTALHIFVVTNQCNLRCIYCQAQDHQHFERG-SMSPETGRRAIDLALQSPNPSLAFEFQGGEPLLAFPVIREMVCYAE 159 Mitsuokella mul...
EED59418      80 NMSASLHIFVVTTACNMGCVYCQANNGTKCSNIF-MDEETAEKAVDIALQSPTRCLSFEFQGGEPLLNFKIIKHIVEYTE 158 Blautia hanseni...
WP_011899284  98 SGGPGLHIFVITLRCGNSCEYCQASRKSVTSSQHDMSQETARNAVDRVFESPNQRITIEFQGGEPLLAFDLIKFIVDYAH 177 Aeromonas salmo...
WP_011790688  94 FDGPALHIFVLTLRCENSCEYCQVTRRSPDAVKYDMPLSIAKQAVLRMFESPAENLTVEFQGGEPLLAYDVLKYIVELCI 173 Shewanella sp. ...
WP_012078870  86 QDGPSLHIIVPTLQCAHSCKYCQVSRSLNDEGH-TIKIEDLDAACESIFESSSPTLTVEFQGGDPLLRFDLVRRAILYIT 164 Janthinobacteri...
WP_015959892  80 LAVRPIFMIVPTLRCDHTCKYCQVSRASATADGYDLNPKLLPQIVSTIKKLGTPPYKIEVQGGEPLLRFDLVQSIYHECE 159 Enterobacter sp...

EDM20916     163 WQNLFKRRELDFVICTNLTLLNEDMVKYLKKHKCMISTSLDGPKDLHDMNRPLQN-KELdHHViFEKNLAMIRQIW---- 237 Bacteroides cac...
EDM58511     162 SNLG--VDQFEIVIATSLSLLNDDVLTWSEDKPINFSTSLDGGAFTHNSNRVLKG-GNS-FEL-VKQGVEKIRRRL---- 232 Vibrio parahaem...
EDM81026     171 ERNKEIKKRLEFTMVSNFALLTEEKLQYLLDNKVQLCTSIDGPEEVHNAQRKLPQtHNA-YQA-AARWIKRVNEAYierg 248 Plesiocystis pa...
EDU59447     160 IVLG--EENIEFVITSSLSLLNDDMIDWSINKPIYYSVSLDGTESIHNKNRILPN-GNS-FQL-VENNIKKLQKAL---- 230 Providencia stu...
EEC93040     160 AQRG--KKQVSFTVVSNLSLLTDEMADFFQEHRVTVCTSLDGPAAIHETNRRAQAvGMSsYEK-MCAGLQKLHER----- 231 Mitsuokella mul...
EED59418     159 EHNT--NHEINYNVVTNLTLLDDEKIEFFKTYKFGVSTSIDGHEYLHNSNRPFKD-GTPtFTK-VIDSLDKLKNS----- 229 Blautia hanseni...
WP_011899284 178 EKNSVHGKSLVFVIATSLQYITDEMLDFIKLHSIQISTSLDGPEALHNKNRPSSC-GNS-YQS-TLAGIRKVREAI---- 250 Aeromonas salmo...
WP_011790688 174 ELNITEQKSLQFVVATSLQNINMEMLEFFHLHNVHISTSVDGPQWLHQLNRPNSC-SNS-YEK-TMHGLEMARGVL---- 246 Shewanella sp. ...
WP_012078870 165 SLNKSQNRRIRYVVASTLHQLNVEMCLFFKEHKVYLSTSIDGPSRLHNKNRPTPT-RDA-FER-TLQGVALAQKII---- 237 Janthinobacteri...
WP_015959892 160 ISLG--NDAFEMVIATSLSLLDESILSWVKERNITFSVSLDGNEAVHNKNRILTD-FQA-HNK-AVTGIQKITEEL---- 230 Enterobacter sp...

EDM20916     238 ---GDGDcVSALMTTSKHSLGRFKDIIDEYIRLGFNNIFLRSLNPYGFAKQYKEKIAYPVEEFIANYKEGLDYIIELNKQ 314 Bacteroides cac...
EDM58511     233 ---GPDR-VATVTTVTEALLQKPEDIVDAHSDLGFSDMFVRPISPYGFANKGNAK-TYDIKAFMAFYEQLLKVLNRKRLA 307 Vibrio parahaem...
EDM81026     249 ldpSLYH-VEALLTTTKKTLDYHEEVVDTYVKLGCNTIFLRPIDPFGFAERARLRLEYPRSKYLEFYRKSVDYMIELNKQ 327 Plesiocystis pa...
EDU59447     231 ---GKSH-VATVTTVTKALLDSPHLLLDAHQSLEIFDIFIRPISPYGFAKNKED---YTIDEYLAFYSKLLELVLEKNKQ 303 Providencia stu...
EEC93040     232 ---GIF--PGAVETTTRYTLAHARELLAEYVRQGMQTIFLRPLTPLGFARSDWQAVGYTVDEFLTFYRQALDEIFRLNRE 306 Mitsuokella mul...
EED59418     230 ---GIY--VGAIQTTTRESLKYPVEIVKTYYDLGFDSIFIRPLTPLGKATINWKDIGYTAEEYLEFYLKALEATISLNKE 304 Blautia hanseni...
WP_011899284 251 ---GDEA-IAAMTTITKDSLPFHQEIVDEYVKHGFHSIFLRPLNMYGFAVKRESKVSYTSAEYFAFYQKSLQYIIDINKA 326 Aeromonas salmo...
WP_011790688 247 ---GHDR-IAGMTTITRSSLTAIKTIIDEYVRLGFHSIFLRPLNMYGFAVKKENKVGYSSEDFNKFYEQALKYIIEINQQ 322 Shewanella sp. ...
WP_012078870 238 ---GPDA-VSALMTTTKESLLYPNEIVDEYVRLGFKEIFLRPLSAYGFAKRNQKFLAYTLEDFNQFYLSALERVLYWNQQ 313 Janthinobacteri...
WP_015959892 231 ---GANR-VATVTTVTKELTKEPASIVDAHLSLGLTDMFIRPVSPYGFAQK--QSFTFSMPEYFAFYKELMQEVLIQNEK 304 Enterobacter sp...

EDM20916     315 GTFFVEGFAALLLKRMLTPFATGFVDLQSPAGVGIAGAIYDYDGNVYVSDEARMMARFK-NYYFRLGNVNENSYQEMFNG 393 Bacteroides cac...
EDM58511     308 GERIIEHSALIHLRRIFNADYSGYADLKSPSGLILNCIMFNYDGRIYGSDEARMLQKTNpDIDFSLGTIQEPVIES---N 384 Vibrio parahaem...
EDM81026     328 GVQILERYAAIFLTKILRGEDPNFLDNRNPAGAGIGQIAYSYDGNIYSCDEGRMLAATG-DETFKIGTV-DSAYRQVVGH 405 Plesiocystis pa...
EDU59447     304 GIPFVEHSAAIHIKRINNPNFAGYADLKSPSGLIFNSLLFNYDGKLYGSDETRMLQKVHpDIDFSIGDIELLIFSQ---N 380 Providencia stu...
EEC93040     307 GVRLREQHAVFFLRKILQGRADNYMELRSPCGAGFGQLAYYYNGDVYTCDEGRMVAEAG-DPAFRLGNVYRDTYASLMRS 385 Mitsuokella mul...
EED59418     305 GRFFKEEHATILLKRI-SGFFVNYMELRSPCGAGIGQLAYYADGNIFTCDEGRMLYEMG-NEAFKLGNVNSSTYSTLIGN 382 Blautia hanseni...
WP_011899284 327 GYYLDEVTASLALNNMLTGRAVGYVDLRSPCGDGTGVLVYHYNSYVYPSDEARMLYDMG-DNKFCLGSV-EAPYVELISS 404 Aeromonas salmo...
WP_011790688 323 GYRLDEVNAALALNNILTPQATGYVDMRSPCGDGTGVLVYNYDGKVYPSDESRMLVEMG-DESLALGSV-SESYQDLMSS 400 Shewanella sp. ...
WP_012078870 314 GVELREVYTSIILNKLLSTFDSGYVDLQSPTGAGLSTLVYNYDGFVYPSDEARMIAETG-DQSLRLGRI-GEAIASLLSS 391 Janthinobacteri...
WP_015959892 305 GIPVIEHSAAIHLKRIFNPGFSGYADLKSPSGVVLNCILFNYDGKVYGSDESRMLQKVNpEADFSAGEFASLSFSS---N 381 Enterobacter sp...

EDM20916     394 ELLHHIIASACNECLPVCAECVFQPYCGADPVRNMSEQGDMIGFRPTNEMCKKTKAIIHYLFELLQKHDPEINRIFWSWL 473 Bacteroides cac...
EDM58511     385 SLYKSILSQSFISVHPGCASCVYQPFCGSDPCQNISVFGEPIGDKSLSRFCQYHKAMFTLILKHLY-AEDGIGEMLKEWL 463 Vibrio parahaem...
EDM81026     406 ETVRAMAIATNLDQQPDCVNCAYNPYCGTNAAYNYKAQGSIFGRMRDNNVCAVHKGIQDYLFEKLAENDPETMQIFERWT 485 Plesiocystis pa...
EDU59447     381 PIYHQLLSDSLNMLHVGCDNCAYQPFCGVDPCQNISLFGEPIGNKSLSRFCLYHKGMFNLLLSKII-KNNEDAKILKEWS 459 Providencia stu...
EEC93040     386 DTCRATSVASVLESLPGCCDCAYQPYCGVCPVVQYASSGNIFPREANTYRCQIYKGILDTLFAILKHGSEEEREILKAWV 465 Mitsuokella mul...
EED59418     383 SACKAICASTILESIPTCCDCVYQPYCGTCPVVSYAATGDIIEKSPRGYRCKIYAGMLDKLFLLLKENDTQIVHILQTWS 462 Blautia hanseni...
WP_011899284 405 DVMGEILMSGVAESLPACAYCAYLPYCGANPIQNYSRTGDLGGHRAKNDFCNKQKPLYRHLFSLL----EENKDVFTSWV 480 Aeromonas salmo...
WP_011790688 401 SVLNTILHAGIAEALPGCSDCAYLPYCGANPIQNYSRYGDMIGHRTFSAFCAKQKFIYRYVFNLL--QDKSNRTVFNSWL 478 Shewanella sp. ...
WP_012078870 392 DIQKNLINASLVDLVPGCKECAYNQFCAPNPVDSQAQFGTPFAPVHLTEHCRRHMWLFDYVFSIVKNADDDLLDLFCRWA 471 Janthinobacteri...
WP_015959892 382 EYYRSALSSSFNFAMPGCDTCAYQPFCGADPCQNISVHGEPVGDKSRSTFCQYHKGMFRFLLNEI-SQDGPMAKMLKGWA 460 Enterobacter sp...
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