Conserved Protein Domain Family
Rv0697
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TIGR03970: Rv0697 
dehydrogenase, Rv0697 family
This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function.
Links
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Statistics
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PSSM-Id: 274888
Aligned: 6 rows
Threshold Bit Score: 670.754
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_003941995   7 ADFLVVGGGTCGCVVAARLSEDPSATVMLLESGSGYRSAlELPDVLGDPYRLPVGPASEYTWTYPVELT--PRRAS---- 80  Rhodococcus ery...
WP_003403503   8 SDVLVVGAGSAGSVVAERLSMDSSCVVTVLEAGPGLADP-GLLAQTANGLQLPIGAGSPLVERYRTRLTdrPVRHL---- 82  Mycobacterium t...
WP_011778566   3 SDVLIVGAGSAGSVLAERLSADDGCQVTVVEAGPGPFDP-RVGTQITDGLRLPIGVASSVVRRYPTALTdePRRHA---- 77  Mycobacterium v...
WP_014877070   2 SDVLIVGAGSAGSVLAERLSADPSCQVTVVEAGPAPSDP-RVAAQITDGVRLPIGAASSVVRHYGSTLTedPPRRT---- 76  Mycobacterium s...
WP_011598115   8 advvvvgggssgcvvAARLSENPGRSVLLLESGPGYRTVsDCP--VLDYRTLPVGPGSAFAETYGVELA--PSVPS---- 79  Rhodococcus jostii
WP_011211599   2 TDTLIVGGGTAGCVLAARLSEDPAHTVRVLEAGPVWLEPqRWPAALRDAGRMPIDPTAPWLWRYTSTLDdgAGAAAavvg 81  Nocardia farcinica

WP_003941995  81 TIARGRTLGGSGAVNGAYFTRATRADFENWP----SSWRYDDVLPYFKKSETDRDF-EGEFHGTAGPIPVERRAwdQLHP 155 Rhodococcus ery...
WP_003403503  83 PIVRGATVGGSGAINGGYFCRGLPSDFDRASi---PGWAWSDVLEHFRAIETDLDF-ETPVHGRSGPIPVRRTH--EMTG 156 Mycobacterium t...
WP_011778566  78 QIMRGAVVGGSGAVNGGYFCRALPSDFDGWGi---AGWSWDEVLPHYTAIETDLDF-TGPLHGSAGPISVRRVS--EFDG 151 Mycobacterium v...
WP_014877070  77 EIIRGSVVGGSGAVNGGYFCRGLPTDFTAWAv---PGWSWDDVLPHFRAIETDLDF-ATALHGSEGPIKVRRVH--EFDG 150 Mycobacterium s...
WP_011598115  80 AMVRGHVLGGSGAVNGAYFVRGTEADFRHWP----ASWSYEHVLPAFRALERDADF-DDSRHGTTGPMPVRRQPaeRLSE 154 Rhodococcus jostii
WP_011211599  82 QLVRGRVLGGSSSVNGSYFGRARAADFAAWSriagPLWDFDAVLPAYERSERDLDFgDRPGHGAHGPIPVRRTA--TGVP 159 Nocardia farcinica

WP_003941995 156 LSGEFHAAALGAGFPDDVDKNAp-----dSFGVGRVPLNVSDHRRISTAIGYLMPALHRPNLRVESGVNVIRIAFSGTRA 230 Rhodococcus ery...
WP_003403503 157 ITESFMAAAEDAGFAWIADLNDvgp--emPSGVGAVPLNIVNGVRTSSAVGYLMPALGRPNLTLLARTRAVRLRFSATTA 234 Mycobacterium t...
WP_011778566 152 CTASFVESAREAGFGWIEDLNGstperplPAGVGAVPLNINGGTRVGPGGAFLQPALQRANLTLVTDTRVGGLRFSAGRV 231 Mycobacterium v...
WP_014877070 151 CTAAFVDAVSAAGYGWIDDLNGsdadaalPPGVGAVPLNIDGGTRLGPGGAYLQPALDRPNLHLRADTRVRRVLVEHDAA 230 Mycobacterium s...
WP_011598115 155 ISAAFRAAALGAGHPEEPDKNSagg--ggVG---PVPLNVDGGHRVSTAVAYLLPAWKRPNLTVEANSDVVRILFSGNET 229 Rhodococcus jostii
WP_011211599 160 VSRLFADAVRAAGFGERADLNGlpd-agpSTGLAKVPCNVADGRRVGTAAAYLLPAATRPNLRVDGEVPVSRILFRRGRA 238 Nocardia farcinica

WP_003941995 231 IGVDVLGDGNVRRIRADHVVVCSGAVATPHILLNSGVGPAEQLVEQGVSVVLDRPgVGQNFVDHPEVLLPYHFSKPRTIr 310 Rhodococcus ery...
WP_003403503 235 VGVDAIGPGGPVSLSADRIVLCAGAIQSAHLLMLSGVGEEEVLRSAGVKVLMALP-VGMGCSDHPEWVMPTNWAVAVDR- 312 Mycobacterium t...
WP_011778566 232 VGVDCLGPGGPTTLVADRVVLCAGAIASAQLLMVSGVGPQQVLRAAGVAVQIDLP-VGVDTVDHPEWVLPVTWPPTHGVp 310 Mycobacterium v...
WP_014877070 231 VGVECVDG---EILYADRIVLSAGAIGSAHLLLLSGIGPAGDLAAHGIAVAANLP-VGTATVDHPEWVLPVAWTPTHDLp 306 Mycobacterium s...
WP_011598115 230 VGVEVESDGVRRTVRTGRVVLAAGPVETPVLLMLSGIGPAEHLKDNGIPVVLDAPgVGSDFSDHPEVALPYRIRDSLRRn 309 Rhodococcus jostii
WP_011211599 239 VGVEYRRGRAAETAWADRIVLCAGAVESAALLLRSGIGPPGQLRALGITPVQAAP-VGSWCTDHPEIGVEYRLEPEPDRp 317 Nocardia farcinica

WP_003941995 311 sqtPVLETALNLAE-IEIRPYTASFTDLVPG---V---PRMDHGVGVVLMAPHSRGSIELASRDPAGAPRIRYNYVASAH 383 Rhodococcus ery...
WP_003403503 313 ---PVLEVLLSTHDgIEIRPYTGGFVAMTGDgtaG---HRDWPHIGVALMQPRARGRITLVSSDPQIPVRIEHRYDSEPA 386 Mycobacterium t...
WP_011778566 311 ----pLEAVLTTGDgLEIRPYTAGFGAMMTG---RrddPTDQPHLGVTLMQPLSRGRVTITSADPDADPVIEHRYDSEPA 383 Mycobacterium v...
WP_014877070 307 ----pLEAVLTTADgIEIRPYTAGFSALVHG---PehdPAELPHLGVALMRPHSRGRVRLASADPAVPPIIEHRYDTVAG 379 Mycobacterium s...
WP_011598115 310 dtsPVVETVLNVGD-LEIRPYTAPFDVLVPG---S---GQPDPILGIGLMVTDSRGDIRLTSGRRRDRPRIEYRYAQSAA 382 Rhodococcus jostii
WP_011211599 318 ptvP-LEYVLDLDD-IEIRPYTVSFTP-------------DTYRLGVALMRPLAAGELRLRSADPARPPVLEHRYLSAAA 382 Nocardia farcinica

WP_003941995 384 DRAAIREGMRIAENLLESiaetg---lidrPVVEYTDEWvesrlGTSLHMSGSCVMGAEADPFAVVDGRCRVIGAQGLSI 460 Rhodococcus ery...
WP_003403503 387 DVAALRQGSALAHELCGA------------ATRIGPAVW-----ATSQHLCGSAPMGTDDDPRAVVDPRCRVRGIENLWV 449 Mycobacterium t...
WP_011778566 384 DVELLRAGTRLAHELAG-------------ATVQSEASW-----ATSQHLCGTARMG------AVVDARCRVYGVSNLWV 439 Mycobacterium v...
WP_014877070 380 DVDALRAGAELARELVSH------------AVKVGEASW-----STSQHLAGTAPLSA--DGQGVLDPTCRVLGVERLWV 440 Mycobacterium s...
WP_011598115 383 DRRALREGQAIGLELLRSpelgp---llepLSREVSDRAvlahlGTSLHLCGSCRMGGRDDAGAVVDEWCNVRGMEGLTI 459 Rhodococcus jostii
WP_011211599 383 DRDRLCAAAVLATDLLAAvpgarastvappAAGERAAAWlrarlATSQHLSGTCRMGGPEDPAAVVDAHCRVHGLAGLAV 462 Nocardia farcinica

WP_003941995 461 VDTSILPTIPTRGPHATAVMVAERASAILL 490 Rhodococcus erythropolis
WP_003403503 450 IDGSVLPSITSRGPHATIVMLGHRAAEFVQ 479 Mycobacterium tuberculosis complex
WP_011778566 440 VDGSILPAIPSRGPHATIVMAGHRAAEFVS 469 Mycobacterium vanbaalenii
WP_014877070 441 VDGSIMPAITSRGPHATIAMIGHRAAEFIA 470 Mycobacterium smegmatis
WP_011598115 460 ADTSVFPVVPSRGPHATAVMVAERVSTFLG 489 Rhodococcus jostii
WP_011211599 463 VDLSIVPVPLSRGPQASAVMLAERAAEFLR 492 Nocardia farcinica
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