Conserved Protein Domain Family
metzin_BF0631
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TIGR03952: metzin_BF0631 
zinc-dependent metalloproteinase lipoprotein, BF0631 family
Members of this protein family are zinc-dependent metalloproteinases, related to ulilysin and other members of the pappalysin family. Members occur as predicted lipoproteins and occur mostly in the genera Bacteriodes and Prevotella. [Protein fate, Degradation of proteins, peptides, and glycopeptides]
Links
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Statistics
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PSSM-Id: 274876
Aligned: 8 rows
Threshold Bit Score: 418.804
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
ZP_06419980  19 LLFLMVVGLLLVSCKSED-------------------------------------------------------------- 36  Prevotella bucca...
ZP_05916839   8 LFMVVAALVLLVACSKDE-------------------------------------------------------------- 25  Prevotella sp. o...
ZP_06423792   8 LFMVAAALVLLNACDKKD-------------------------------------------------------------- 25  Prevotella sp. o...
ZP_06253468   6 YFMIALTVLSFASCKDTE-------------------------------------------------------------- 23  Prevotella copri...
ZP_06406153  12 ILCCLFAIVALMACDKEPfdngkt-------------------------------------------------------- 35  Prevotella sp. o...
ZP_01961348   5 LIFLLPLLWLLIGCEDSE-------------------------------------------------------------- 22  Bacteroides cacc...
ZP_06268715   8 WAMPIAALFLLGSCNDNEieqtsqlnvdnseikaplegtvvklaieanvkwtlrtnhswlttsvtqgegsdvvtvtipen 87  Prevotella bivia...
ZP_06268609   5 LLLLLCIVGLFTACSNYA-------------------------------------------------------------- 22  Prevotella bivia...

ZP_06419980  37 ----------DLSLetagi---dqdedNTTAKLDESYVYQLPVVFHVLYQDASDKSQYVDAN-RLKEILQNVNDLWKGnI 102 Prevotella bucca...
ZP_05916839  26 ----------LRTS-------------PGPEPIDPTVVSILPVVFHVFYADENDATQKVPAN-RLRQVLNNVNELYRG-T 80  Prevotella sp. o...
ZP_06423792  26 ----------DRTTi------------PKPEPEEPIKLGVLPVVFHVFYADENDATQKVPAE-RLRQVLDNVNRLYQG-V 81  Prevotella sp. o...
ZP_06253468  24 ----------Gsigdpii---shgqdrDTDIITGDDYVYHLPVIFHVFYR---DSTQYIEYT-RLKEILSNVNELYQGdV 86  Prevotella copri...
ZP_06406153  36 ---------------------lkkeekEAPKEINDNTLYELPVVFHVL-SNSTTKQEYIPNDvDLRRLLFYVNELYAGgI 93  Prevotella sp. o...
ZP_01961348  23 ----------PESKp------------DSTDPPLIEYHYELPVVFHVLYQ---NEQQNIKKG-RIQEIITDCNKYYQNrL 76  Bacteroides cacc...
ZP_06268715  88 lyrgnrtdsiQIASvdgtavkiikveqATTTKLTEDYHYKLPVVFQIIYSDSTKNLEDMSQS-YLTTVLGRVNEIY---- 162 Prevotella bivia...
ZP_06268609  23 ----------DINTeskp-----isgkHYTLQELEPMTYKFKVVFH-FLQNNKSELSAVHTT-HLQAIIDAINNFYVGnT 85  Prevotella bivia...

ZP_06419980 103 YG------ESENMGVHFVLAKQDEAGKTMPIPGVEYIKYEg-TYPIDAYDFM---KQKS---NLKYIWDPNEYINVMVYN 169 Prevotella bucca...
ZP_05916839  81 YS------GGESTNIAFTLASTADAGKRLDAPGVEYIKLGknEYPIDPYVLM---NDKTg-kFKQYMWDPNKYINVYVYH 150 Prevotella sp. o...
ZP_06423792  82 YS------GAGNANIRFLPTPVDKAGKRLAESGVEYIKLEksEYPIDPYVLM---NDKSg-kYKQYMWDPNRFVNVYVYH 151 Prevotella sp. o...
ZP_06253468  87 YNyqmdtiPSENLHILFELAEKNESGKRLSTPGVEYIKVP--ESEFDCESFM---KDKk---NAKYCWDQNNYINVMVYA 158 Prevotella copri...
ZP_06406153  94 YG------PSVNIRVKFVTATEDEEGKKMTTQGVVYDKWDe-KYPINCEDFM---TNNSn-kYTKYLWDPNKYINVFVYL 162 Prevotella sp. o...
ZP_01961348  77 GS------NSVDMNLEFVLATENPQGVKLDEPGVHPIQVS--NPVQDCEVFM---TDKA---NLKYLWDTDKYINIMLYP 142 Bacteroides cacc...
ZP_06268715 163 --------EKSGANVEFVLATETPNGKKMDIAGINRTKLS--IKSINTDAFMgytKDAPa-eYKNILWDQDRYINICLFD 231 Prevotella bivia...
ZP_06268609  86 --------NETNTKVVFELADNAPQGKTLSEKGITRYNIT--EDSISYNALI---NEKPgdkFYDMGWDRANYINIYVYT 152 Prevotella bivia...

ZP_06419980 170 FKEEE-KSGLLLGISHMPLTIKSDSALAGLETTEYRKIPKNRLSYAPCTSINSSLhngksiINTQSTRYTlADKGKKG-Y 247 Prevotella bucca...
ZP_05916839 151 FSQTK-ENATTLGVSHMAVSSKGNHELEGLVVANSNYLTLENLTTPFCVSVNSKY------VNEESNRYN-DWPNLRT-F 221 Prevotella sp. o...
ZP_06423792 152 FKQTN-TNGTTLGISHMAISAKGEHELEGLLAVQARHLTLDNLPTPFCVSVNSKF------VNDESNRYK-DWPNLHF-L 222 Prevotella sp. o...
ZP_06253468 159 FKKTD-ENSTTLGISHLPYQVGGYPQIDGLG--DGKNYPLSKLGKPYCVSLNSIYv----gREYEGTRYT-TDKNHKG-Y 229 Prevotella copri...
ZP_06406153 163 FDDDD-NEAEVLGISHMPYKTKENATLQGLEQVASGKMTKKNIAFPLSVSINAKY------INTLSARYSsGLKEKTF-R 234 Prevotella sp. o...
ZP_01961348 143 FKQDEnSEGVILGISHLPYTIKPD-YLEGLNQLNG-IPSHSSLKYPHCISINNTY------IN--------STPSNESkK 206 Bacteroides cacc...
ZP_06268715 232 FADED-----VAGISCFPYTIAPD-TLIGLTKLNH-WVKPNELILPYCVALNTAY------LK--------DFPQ----T 286 Prevotella bivia...
ZP_06268609 153 TKEKN-----IGGVSTLPKMPKSV-AKDGDIVASGNEYTSYNVSVTLQKALLGLW------LK-IEKKYPnISPAK---V 216 Prevotella bivia...

ZP_06419980 248 EYSSADVNVTLAHELGHYLGLHHVFAEEKndkgytSIDDCQDTDYCEDTPSYNILEYNK-------MLTQYIKQKKQ--N 318 Prevotella bucca...
ZP_05916839 222 TIHSADFNVTLAHELGHYLGLFHVFGEENk----vYIDGFKDTDYCKDTPTYNKVAYDK-------FFIEYLKTHSG--H 288 Prevotella sp. o...
ZP_06423792 223 RINSADFNVTLAHELGHYLGLFHVFGEEDg----eYIDGFKDTDYCKDTPTYNKVAYDK-------FLAEYIRTHYA--Q 289 Prevotella sp. o...
ZP_06253468 230 TYNTADPNATLAHELGHYLGLFHCFSEKTtkesseAADDDDDSDYCDDTPSYNRIAYGK-------WLTEYVSKAQAikK 302 Prevotella copri...
ZP_06406153 235 GYKEEDVVVTLAHELGHYLGLFHVFAEDSkn---gVVDQCFDSDYCQDTPSYNKKQYER-------DLQELSK------H 298 Prevotella sp. o...
ZP_01961348 207 IYSSTDIVATIAHELAHYLGLFHTFSESDde----gLNTCMDTDYCDDTPTYDREAYSN-------WMQSYIESKNGikN 275 Bacteroides cacc...
ZP_06268715 287 LTRSSNFAESIAHELGHYFGLRHVFGEGKts-----dDATKDTDYCTDTPTYHRKNYVI-------NVSNYIRKHP---N 351 Prevotella bivia...
ZP_06268609 217 IPSDSNPVNVLAHELGHYLGLYHVFHTKE-----------ADNDYCEDTKEYDRNEYMKrvdaaqpTIDAAIKANDA--K 283 Prevotella bivia...

ZP_06419980 319 HeqVQMKDVAKRI--NC-SNESFLSENYMDYAISYSFRFTPDQKKRVRNVLYYSPLIPGPK 376 Prevotella buccae D17
ZP_05916839 289 N--ADLNELLKRT--GS-DGKTFTSNNIMDYALSLGHTFTKNQTERMYHVLGYSPLMPKTG 344 Prevotella sp. oral taxon 472 str. ...
ZP_06423792 290 A--ADLKELLKRT--GS-DGKTFDSNNIMDYAISLGHTFTQDQTERMRHVLNYSLLIPRPG 345 Prevotella sp. oral taxon 317 str. ...
ZP_06253468 303 DttLSMRELAKRT--NS-KDEEWQSDNLMDYSICYSMRFTPEQANRIRQVLYYSPLIPGPK 360 Prevotella copri DSM 18205
ZP_06406153 299 LtyENVHEIFQRT--DC-SGKVYEATNIMDYAYCYSYAFTPNQQYRMRQVLYYSPLIPGPK 356 Prevotella sp. oral taxon 299 str. ...
ZP_01961348 276 MslSEFNKLFERK--DCvTNLTSTPNNIMDYDISWVNRFTPNQQERIRYVLMHSPLVPGPK 334 Bacteroides caccae ATCC 43185
ZP_06268715 352 LtdADLPFLLKRVvpNTkPKQTFESTNVMDYYFTRQNEFTPEQVARIRYVLLNCPYVPGPK 412 Prevotella bivia JCVIHMP010
ZP_06268609 284 AyyAAIDPLFMRT--PMnGGSSFRSVNIMDYYYTDANKFTADQVKRIRRHLYYSTTIPGPK 342 Prevotella bivia JCVIHMP010
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