Conserved Protein Domain Family
butyr_acet_CoA

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TIGR03948: butyr_acet_CoA 
butyryl-CoA:acetate CoA-transferase
This enzyme represents one of at least two mechanisms for reclaiming CoA from butyryl-CoA at the end of butyrate biosynthesis (an important process performed by some colonic bacteria), namely transfer of CoA to acetate. An alternate mechanism transfers the butyrate onto inorganic phosphate, after which butyrate kinase transfers the phosphate onto ADP, creating ATP. [Energy metabolism, Fermentation]
Statistics
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PSSM-Id: 188463
Aligned: 7 rows
Threshold Bit Score: 909.604
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_02092519   11 DCKELYAQKLMTAAQAAALVKSGDWVDYGWAVNTPVAVDAELAKRLPELEGVNFRGGILMWVPEIFQIDDPAAHMTWNSW 90  Faecalibacteriu...
AAX19660       2 DFREEYKQKLVSADEAVKLIKSGDWVDYGWCTNTVDALDQALAKRTDELTDVKLRGGILMKPLAVFAREDAGEHFCWNSW 81  Roseburia sp. A...
AAZ23219       2 SFIKEYAQKLVTAEEAVKVVKSHDWVDYGWTTGTPVALDAALAARADELEDVKVRGGILLREPEIFKVDNVAEHFTWNSW 81  [Eubacterium] h...
ZP_02418566    2 SFKEEYQKKLKTADEAVKVVKSGDWLEYGWCVTTPAALDKALAKRMPELENINIRGGIVMWPLEITKIDSPADHFTWNSW 81  Anaerostipes ca...
EEG66311       2 DYKNMYDQKLVSADQAAAVVKSGDWVDYGWTTGTTVAFDAALAKRMPELHDVNLRGGILMWVPEVFKIENPAEHFTWNSW 81  Clostridium sp....
ZP_02861109    2 DFKQEYGQKSVTAAEAVKAVKSGDWIDYGWTTTTPVAFDKELAKIMPNLKDLNIRGGILMWEPEIFKLENAKDHFTWNSW 81  Anaerofustis st...
WP_012743830   2 SFLEEYKQKLVSADEAVKIVKSGDWVDYGWCTGTPDALDKALARRTDELKDVNVRGGILLKPLAIFEREDAGEHFTWNSW 81  Eubacterium rec...
ZP_02092519   91 HMGGIERKAIAQGFSFYSPIRYSELPRYYRESNDP-VDVAVFQVTPMDEHGYFNFGPSASHLGAVCEKAKKIIVEVNTNM 169 Faecalibacteriu...
AAX19660      82 HMSGIERKMINRGVAYYCPIRYSELPRYYRELDCP-DDVAMFQVAPMDAHGYFNFGPSASHLGAMCERAKHIIVEVNENM 160 Roseburia sp. A...
AAZ23219      82 HMGGLERKAISKGFAFYSPLKYSELPRYYRENIKH-LNVAMFQVAPMDKHGFFNFGPNASHMMAVCETADVIIVEVNENM 160 [Eubacterium] h...
ZP_02418566   82 HMGGLERKWIKEGFSYYAPIRYSELPGYYRNYIDH-VDVAMMQVAPMDEHGFFNFGPSASHLAAMLEKADCVIVEVNENM 160 Anaerostipes ca...
EEG66311      82 HMSGIERKAIAQGFAYYAPIRYSELPRYYRESSTP-LDVAVFQVAPMDEHGFFNFGPNASHMAAVCEKAKVVIVEVNENM 160 Clostridium sp....
ZP_02861109   82 HMGGIERKAIAKGFAFYAPIRYSELPRYYRDGNTPgADIAVMQVAPMDNHGYFSFGPSASHLMAACENAKKVIVEVNENV 161 Anaerofustis st...
WP_012743830  82 HMGGYERKLIKRGCSFYSPIRYSELPRYYRDSTTP-DDVAMFQVAPMDSHGYFNFGPNASHLGAVCETSKKIIVEVNENM 160 Eubacterium rec...
ZP_02092519  170 PRCLGGMENCVHVSQVSGIVEGANPPIGQMAAAGAATEVDLKVANLIVPQIPNGACLQLGIGGMPNAIGGLIAQSDLKDL 249 Faecalibacteriu...
AAX19660     161 PRCLGGTECGIHISDVTYIVEGSNPPIGELGAGGPATDVDKAVAKLIVDEIPNGACLQLGIGGMPNAVGSLIAESDLKDL 240 Roseburia sp. A...
AAZ23219     161 PRCLGGFEEGIHISRVDYIVEGQNPAIGELGAGAPPTEVDRAVAQLIVEEIPNGACLQLGIGGMPNTVGSMIAESDLKDL 240 [Eubacterium] h...
ZP_02418566  161 PRCLGGFEEGVHISKVDMIVEGENPAIAELGGGGAATDVDKAVAKLIVDQIPNGACLQLGIGGMPNAVGSMIAESDLKDL 240 Anaerostipes ca...
EEG66311     161 PVCLGGFENCVHISDVDMIIEGDNPAIGEMGGGAAASEVDEAVAKLIVEEIPDGACLQLGIGGMPNAVGSLIAKSDLKDL 240 Clostridium sp....
ZP_02861109  162 PRCLGGYEEAIHISKVDMIIEGDNPPMAEMGGGGAATEVDKTVAELIVEEIPNGACLQLGIGGMPNAVGSLIAESDLKDL 241 Anaerofustis st...
WP_012743830 161 PRCHGGSEANVHISQVSYIVEGDNPAIGELGAGGPATDVDKKVAELIVDQIPNGACLQLGIGGMPNAVGSLIAESDLKDL 240 Eubacterium rec...
ZP_02092519  250 GVHTEMYVDAFVDIAKAGKINGSRKQLDKGRQVYAFGAGTQKMYDYLNDNPECMSAPVDYTNDIRSISALDNFISINNAV 329 Faecalibacteriu...
AAX19660     241 GVHTEMYVDAFVDIAKAGKINGSKKNIDRYRQTYAFGAGTKKMYDYLDDNPELMSAPVDYTNDIRSISALDNFISINNAV 320 Roseburia sp. A...
AAZ23219     241 GVHTEMYVDAFVDIAKAGKINGLKKNIDKGRQVYAFGAGTKKMYDYLDDNPECMSAPVDYTNSAKTIAQIDNFISINNAV 320 [Eubacterium] h...
ZP_02418566  241 GVHTEMYVDAFVDIAKAGKITGARKNIDRYRQTYAFAAGTKKLYDYLNDNPECMSAPVNYTNDIARVSSIDNFISINNAV 320 Anaerostipes ca...
EEG66311     241 GVHTEMYVDAFVDIAKAGKITGAHKAIDKGRQVYAFGAGTKKLYDYLHNNPECMSAPVDYTNDIRSISALDNFMSINNAV 320 Clostridium sp....
ZP_02861109  242 GVHTEMFVDGFVDIANAGKINGSKKNLNRFRQTYAFGAGTKKLYDYLDNNPECMSAPVDYTNDVRIISAHDNFISINNAV 321 Anaerofustis st...
WP_012743830 241 GVHTEMYVDAFVDIAKAGKITGAKKNIDRYRQAYGFGAGTKKMYDYLDENPELMSAPVSYTNDIKNIAALDNFISINNCV 320 Eubacterium rec...
ZP_02092519  330 DIDLFGQVNAESAGVKHISGAGGQLDFVLGAYLSKGGKSFICLSSTfFNKKTGQLESRIRPTLENGSIVTDTRANVHYLC 409 Faecalibacteriu...
AAX19660     321 DIDLYGQVNAESAGIKQISGAGGQLDFVLGAYLSKGGKSFICLSST-FKTKDGQVQSRIRPTLANGSIVTDARPNTHYVV 399 Roseburia sp. A...
AAZ23219     321 DIDLYGQVNAESAGVKQISGAGGQLDFVQGAYLSKGGKSFICCSST-FTSRDGVKHTRIRPTLAEGSTVTDTRPNTHYVV 399 [Eubacterium] h...
ZP_02418566  321 DVDLYGQISAESSGIKQISGAGGQLDFVMGAYLSNGGKSFVCLSST-FTDKAGQMHSRILPTLHNGSIVTDTRANAHYIV 399 Anaerostipes ca...
EEG66311     321 DVDLFGQVNAESAGIKHISGAGGQLDFVLGAYLSKGGKSFICCSST-FKGKDGSLQSRIVPTLNPGSIVTDTRANIHYLV 399 Clostridium sp....
ZP_02861109  322 DIDLFGQVSSETSGTKQISGAGGQLDFVLGAYLSKGGKSFICLSST-FKNKQGELKSRILPTLHPGSVVTDTRANTHYVV 400 Anaerofustis st...
WP_012743830 321 DLDLFGQISSETSGTKHISGAGGQLDFVLGAYMSNGGKSFICCSST-FTDKQGVVHSRIRPTLVEGSVVTDTRANTHYIV 399 Eubacterium rec...
ZP_02092519  410 TEYGCVNLKGLTSWEKAEALISVAHPDFREELIREAEKLHIWRRSNK 456 Faecalibacterium prausnitzii M21/2
AAX19660     400 TEYGKVNLKGLSTWQRAEALISIAHPDFRDDLIKEAEQMHIWRRSNR 446 Roseburia sp. A2-183
AAZ23219     400 TEFGKVCLKGMSTWQRAEALISIAHPDFRDELIKEAEKMQIWRRSNK 446 [Eubacterium] hallii
ZP_02418566  400 TEYGMANMKGLSAWQRAEALINIAHPDFRDQLIKDAEKAQIWRRSNK 446 Anaerostipes caccae DSM 14662
EEG66311     400 TEFGKVNLKGLTTWQKCEAIISVAHPDFRDQLIAEAEKMHIWKKSNK 446 Clostridium sp. M62/1
ZP_02861109  401 TEYGKVNLKGLSTWQKAEALISIAHPNFRDELIKDAENMNIWRRSNK 447 Anaerofustis stercorihominis DSM 17244
WP_012743830 400 TEYGMVNVKGLSTWQKAEAIISVAHPDFRDELIKEAEKMHIWKRSNK 446 Eubacterium rectale
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