Conserved Protein Domain Family
pyrrolys_PylC

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TIGR03909: pyrrolys_PylC 
pyrrolysine biosynthesis protein PylC
This protein is PylC, part of a three-gene cassette that is sufficient to direct the biosynthesis of pyrrolysine, the twenty-second amino acid, incorporated in some species at a UAG canonical stop codon. [Amino acid biosynthesis, Other]
Statistics
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PSSM-Id: 188424
Aligned: 4 rows
Threshold Bit Score: 607.993
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEN15950       2 LVAIMGGKLQGVEAAYLSRQAGWKAVLVDRNRDAPAAGMCDNFIQADLM-EKDKLVDLFKKVKLVIPAVENSEVLENIKE 80  Desulfotomaculu...
WP_011462268   2 RVGIIGGKLQGVEAAYLAKKAGWDVVLFDRRKKAQGAQLADVFHCMDILrSREEFVAELKGVNLILPAIEDLEVLTALAD 81  Desulfitobacter...
WP_011033389  11 TICLIGGKLQGFEAAYLSKKAGMKVLVIDKNPQALIRNYADEFQCFNITeEPEKLVAISKNVDAILPVNENLECIEFLNS 90  Methanosarcina ...
WP_011500098   3 TVCLIGGKLQGFEVTYLAKKAGMGVVLIDKNRKPLIRNVVDELFCFDITeEPERFIEISKNVDAIIPVNENLDTLNFIRD 82  Methanococcoide...
EEN15950      81 CALAAGVKIIYDSAAYALSSSKIESDKLFARLDLPVPKPWSGCGFPVVIKPSGASGSENVYKINSLRDFNELtLKLGNLD 160 Desulfotomaculu...
WP_011462268  82 IGQRTHIPCVLDLDAYRISSSKQRSNQLFAAMGVPAPRPWPDCHFPMLLKPSDGSGSEGVQVIPCREKLERL-LHQESRD 160 Desulfitobacter...
WP_011033389  91 IKEKFSCPVLFDFEAYRISRDKRKSKEYFASIGTPTPQDKP-SEPPYFVKPPCESSSVGARIIHDRKELKEL------EP 163 Methanosarcina ...
WP_011500098  83 ISNKLDCPVLFDFDAYHISMDKKRSKEYFTSIDIPTPGDRP-SQPPYFVKPPCESSSIGTHIIYDDSELADV------GP 155 Methanococcoide...
EEN15950     161 SWVKQEYLRGPSYSIEVIGCKGDYQTFQITELEMDAAHDCKRVLAPAQLSTEKQDEFKSQAVKIARALNLNGIMDVEVIL 240 Desulfotomaculu...
WP_011462268 161 NWVLEEYLEGPSYSIEVMGFSGNYQVFQITELEMDAQYDCKRVLAPARLDLGLKREFEEMALKLAGELSLQGIMDVEVIL 240 Desulfitobacter...
WP_011033389 164 GMLIEEYVEGEVVSLEVIGDGNNFAVVKETLVHIDDTYDC-HMVTPLPLD----PSFRELSYSLAANLPLKGIMDVEAIS 238 Methanosarcina ...
WP_011500098 156 NMLVEEYLEGNVISLEVIGDGKHFAVVKETKVHIDDTYDC-HMITPVEHD----PKFREISYRLAQGLNLKGIMDVEAIV 230 Methanococcoide...
EEN15950     241 HDEKFKVLEIDARLPSQTPTVVYKATGINMLEVL---WPG----GLKRREKQEIGMTRGVVYEHIKVRSNRlIEVGGEHI 313 Desulfotomaculu...
WP_011462268 241 HAGKLKVLEIDARLPSQTPIAVFHSTGFNMVEYLgkaFVQgkmpGPRLKRARQKGAEKPVILEHFLVTPEK-IEACGEHI 319 Desulfitobacter...
WP_011033389 239 GPLGLKVIEIDARFPSQTPTAVYYSSGINLIELLfraFNG----G--IEEIKTLPEDRYCIYEHLMLAENGvLIPVGEQV 312 Methanosarcina ...
WP_011500098 231 SEKGLKILEIDARFPSQTPIVVYHSSGMNLVALLmqaFTE----G--VTEIERAPEKSYCIFEHLKWDSSG-LIPVGEHI 303 Methanococcoide...
EEN15950     314 MAGAGRLHILKKFFGADEAISNYDRDKTEWVATLIITGKNRQEAWLKRTAVIKNIMQEF 372 Desulfotomaculum acetoxidans DSM 771
WP_011462268 320 LGEAGPLHVLRDFFGADEVLTDYTWGKKEWVLTLMTWGSSPVEVWAKRDQVLKRIQEEL 378 Desulfitobacterium hafniense
WP_011033389 313 LSMGNDY----GNYYEEPGIEIFLCKGENPVFTLVFWGRDREEAEARKNKGLSILKSRF 367 Methanosarcina mazei
WP_011500098 304 LSMGERY----ELFHEEENLEIFHSSGENDVFTLISRGKDIESTEEVRSKGIMRIEDHF 358 Methanococcoides burtonii
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