Conserved Protein Domain Family
prc_long_Delta

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TIGR03900: prc_long_Delta 
putative carboxyl-terminal-processing protease, deltaproteobacterial
This model describes a multidomain protein of about 1070 residues, restricted to the order Myxococcales in the Deltaproteobacteria. Members contain a PDZ domain (pfam00595), an S41 family peptidase domain (pfam03572), and an SH3 domain (pfam06347). A core region of this family, including PDZ and S41 regions, is described by TIGR00225, C-terminal processing peptidase, which recognizes the Prc protease. The species distribution of this family approximates that of largely Deltaproteobacterial C-terminal putative protein-sorting domain, TIGR03901, analogous to LPXTG and PEP-CTERM, but the co-occurrence may reflect shared restriction to the Myxococcales rather than a substrate/target relationship.
Statistics
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PSSM-Id: 274843
Aligned: 6 rows
Threshold Bit Score: 1334.42
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDM74020       36 DDPAQLRVLDWTLWNVSKYYVESKRVEPAAMTLAGLEALEAIIPEVLVEPTDeTKAAVRVRVGTTEQVF-PADANALWAV 114  Plesiocystis ...
EEJ01102       24 HDLSALDVFNVTLVRVRDAYVDPSRIDPKNMLYSALDSVQFNIPEVLIDPYP-EEERVIVHVNDQKKSFsTKAVDSPWRL 102  Haliangium oc...
EDM79842       53 LDERSFPLLIWSIHTVSQDYYDKTRFDPRGQLLAATDRLGLHTPEFFAVPDAsDPGQLEVTVRDQSKRFaIGELKGLDPA 132  Plesiocystis ...
WP_011555759   59 HDLNSLRVLTKVILYVKENYVDPKRVKPKEMMIASLEYVEKSVPDVLVDGNA-ETGKLNVNVNGKQREFdIAHVDSLWKM 137  Myxococcus xa...
WP_012098730   67 YRLDRLPILSQVILKVKDNYVDPARFDPKKMVVASLESVERAVAEVMVQGDE-KSPKLTLTVGSSQRDLdLTGVDSIWKI 145  Anaeromyxobac...
WP_012239069   53 YDLTRLEAVNETLKMIRDKYVEPDRVKPKEMLLSALNAVQRDVAQVIVL-NE-DPNEVTVRVETSEKKFrIDNIQGPWDV 130  Sorangium cel...
EDM74020      115 GPQVRAVFSFVNDHATlTDDEQREAEYAIVEGVLSTLDPHTNLLRPAAFEDMRTNTAGAFGGLGIEVGMRDNELTVLRVL 194  Plesiocystis ...
EEJ01102      103 SGKLKEIFRFIETHMN-PGADLAQVEYAAINGMLNTLDPHSVLLDPETAREMDMNTSGKFGGLGIVVGMRNRKLTVLRPI 181  Haliangium oc...
EDM79842      133 ADRLEEILEFTASVLSlEAEPLHELEYAAINGFLSPLDPHTILLTPEESAELGVKTRGSFGGIGAEIVARDRRILVVRVI 212  Plesiocystis ...
WP_011555759  138 SFALKDVFDFLSKNMR-PIEDTRDVEYAAVNGMLSTLDPHSVLLRPELYREMKLSTKGEFGGLGFVIQMREGNLTVVKVI 216  Myxococcus xa...
WP_012098730  146 RLVLGEAMGFIQDHLV-AHKELKDIEYAAVAGLLSTLDPHTNLLEPKYFKEMKLQTRGEFGGLGFVIAMRDGNLTVVKVL 224  Anaeromyxobac...
WP_012239069  131 SARLREVFTFLQKNLRgTEVDLRDVEYAACNGMLHTLDPHSSFLSPEAYKEMNLSTSGAFGGLGVVISIRDQMLTVLNPM 210  Sorangium cel...
EDM74020      195 PGNPAARAGLQAGDKIVQIDDESTVTMTLNESVGLMRGPAGTEVAIYVRRE---GlDRAKRFDIERAMIKLDSV-TGDIL 270  Plesiocystis ...
EEJ01102      182 KGTPAERAGILRADHIAKIDAELTENLTLQEAVDRMRGAPDTKVTLWIRRK---GeSELLRFDLDRAIIRVESV-ESRML 257  Haliangium oc...
EDM79842      213 PESPAAKAGLQDNDVILAIDDQSTVNMSSADAQGLLRGPIDTQVVLEVRRG-----DAVVRVEITRGQIAIPTV-IAEML 286  Plesiocystis ...
WP_011555759  217 PKTPAHRSGIQKDDRIKKIGEESTVNMDLNEAVSKLRGPVDSRITITVERD---GwDKPRIMTLSRAMISIESV-QHKML 292  Myxococcus xa...
WP_012098730  225 KNTPAQRAGIKAKDVIARIEEQSTVNMDLQDAVDRLRGKPQTKISITVQRK---G-AEARKLSLLREVINVETVaQAKLL 300  Anaeromyxobac...
WP_012239069  211 PDTPAGRAGLKRLDRIVKINNESTLNMPLDDAVRRLRGDPGTPVTVWVTREgegGwQGPKAFELTREVIKVRSV-ESRAL 289  Sorangium cel...
EDM74020      271 PGKdgqgrdakIGLLQIpRNFSQTTSTELRDKLRDFERA----G---VTGIVLDMRDNPGGLLNAAVEVVDAFVDTGTIV 343  Plesiocystis ...
EEJ01102      258 SKN--------VGYIRI-RQFSGRTGQETREAIDTLEGK----G---AKGWVLDLRSNPGGLLEQAIEVSDLFIDQGTIV 321  Haliangium oc...
EDM79842      287 PND--------VGYLQV-ATFQEDTAEKLLAALQDFQSN----Aq--LAGLVVDLRGNSGGLLAQAVGILNQFVKGGELV 351  Plesiocystis ...
WP_011555759  293 SNN--------VGYIRL-KNFQGNTTRDLEAALTQLRKQadakGg--FKGLVLDMRGNPGGLLEQAIQVSDTFLSSGTIV 361  Myxococcus xa...
WP_012098730  301 EGN--------VGYVRL-SQFSANTTRDLLGALQQQRAQ----AggkLEGLVLDLRGNPGGLLEQAIQVSDLFLSQGVIV 367  Anaeromyxobac...
WP_012239069  290 EGG--------VGYVRL-KTFQATSTAELDAALDGLRSK----Gq--LKGLVLDLRGNPGGLLDQAARIADKFLADGVIV 354  Sorangium cel...
EDM74020      344 STVGESSPR---DESKATGDYr-fADVPLVVLVDQGSASATEIVAGALRNLDRAVILGRRTFGKGSVQVLHDr----rVA 415  Plesiocystis ...
EEJ01102      322 TTVGGRERE---PRRARRQDT---NKKPVAVLVNTGSASASEIVAGALKNLDRALVIGSNTFGKGSVQVLYD------NK 389  Haliangium oc...
EDM79842      352 IVRSALGR----EHQDATEEIvvpMKVPVVTLVDESSASASEIVGGSMKHLDRGVILGRASFGKGTVQELRNa----tPY 423  Plesiocystis ...
WP_011555759  362 ATVGLSDKL---REEKRARATdgeDSYPIAVLVNAGSASASEIVAGALKNLDRATIIGRQTFGKGSVQVLYD------FP 432  Myxococcus xa...
WP_012098730  368 KTVGGGDRQrihEVKEASSDAsdlATLPLVVIVNNSSASASEIVAGALKNNDRALVIGRQTFGKGSVQVLDDlddptgSG 447  Anaeromyxobac...
WP_012239069  355 STVGASEGR---EEKRAKGPGt-ePLYPIVVLVSGNSASASEIVAGALKNNDRAVIVGSQTFGKGSVQLVFPd----vTA 426  Sorangium cel...
EDM74020      416 DTElALKLTIAQYLTPGDVSIQSVGVSPDL----ETIPVYVGKDY--LAYYGrkRFDLVREESLSAHLVHSTAQQQQit- 488  Plesiocystis ...
EEJ01102      390 DGS-KLKLTIAQYLTPGDRSIQSLGIVPDIglqrMLVPEKNDEPTdyLRLLP--PSRSYREKDLRAHLTSRYATDEN--- 463  Haliangium oc...
EDM79842      424 GRPlALKLTIAEYRVAGDRKIQNIGVIPDV----ELLPVELLEYEgvARYYDleRFERQRQRGRTAHLPSAVHDAHIeae 499  Plesiocystis ...
WP_011555759  433 DDS-ALKLTIAKYLTPGDVSIQEVGIVPDI----QLVPTRATDER--VDVFA--PRRSMGEADLDQHFGNPDSSTVAkkr 503  Myxococcus xa...
WP_012098730  448 EQS-ALKLTIAQYLTPGDLSIQEVGITPDV----LLLPGRALKEQ--VNFFA--PPRSMGEADLDGHLMNPGGAGPAeva 518  Anaeromyxobac...
WP_012239069  427 EKA-ALKLTIAQYLTPGDISIQGVGVTPDI----ELDPMTVDELE--MDLTV--QKDGLRERDLSAHLSNARAAAAG--- 494  Sorangium cel...
EDM74020      489 ---------aGPLFFLQQGSVNDGSGLT-----------------------------EGELPPRIDVEEDAAKRAQMLLR 530  Plesiocystis ...
EEJ01102      464 ----------KPTYELPFIYEPPTRPDE-----------------------------NLEAEGAEGIQMEEEPLGDEFVL 504  Haliangium oc...
EDM79842      500 l------alaKSPLMLRYLSYSPQLAQE-------------------------------------ALQASGGDAASRTLR 536  Plesiocystis ...
WP_011555759  504 ed---vlnreKPLESLKYLKVDEKQAQAtakkeegkappktaanakkhgdkdplldvDVAGMGEDLDDQLDAEAQEEIKE 580  Myxococcus xa...
WP_012098730  519 kaeakkrrveKAPLELRYLLDEKEDQVAkalkrdlag------------daaaahedVFELTPEQVEDEEAEADPDRLVE 586  Anaeromyxobac...
WP_012239069  495 ----------KPSEVVRYQLTSADREKM---------------------------------------RERGGDIDEDFSI 525  Sorangium cel...
EDM74020      531 DPEIRMARDLALW-APSHRRSDILANLPQFTAQQVAIEDARIAASLGSKDVDWAEGPAPTDGKA-AKLEVSLStdkrGDT 608  Plesiocystis ...
EEJ01102      505 DFEIALARDVVVR-SAHGRRDEMVEVAAKILEQRQAAEEEKLVEALGKLGVDWRDAPKREEARPqLEASLSTD----KSS 579  Haliangium oc...
EDM79842      537 DPEIRLARDVALKlVGKEGRRAQVDALPAIVEELSKREGEAIRAGIETWKVDWADV---GPVDApLEVAVNIVdtknGEL 613  Plesiocystis ...
WP_011555759  581 DFEVQFARDFVLR-APATTRKEQLKQGKAFIDQKRAEEESRINAAIAALGVDWSAGP--TPKNVqMAVSLTPGp---DAK 654  Myxococcus xa...
WP_012098730  587 DYQIRFARELLKR-APQPARARLMESAKALVAERQAQEDERLEKRLRELGVDWTAEAPAGRGTPrPVVTLTPAp---GKD 662  Anaeromyxobac...
WP_012239069  526 DFPIRFARELAARmPPSTPRLQQLRAMHDYIEQVGKEELGKVAAELTKLGVDWSDAPEAVTPAAkSELDVKVEtdrpNAE 605  Sorangium cel...
EDM74020      609 IAGGESGVLTMTVTNAGDAPAYRVRALSDSDYN-YFDERELMFGRIDPGETKTATLKL---------------------- 665  Plesiocystis ...
EEJ01102      580 YDAGDTVTLSGTVTNQGQGPAYRVHARVASDDM-VFEDTEMVFGYIPAGESRTWKVQV---------------------- 636  Haliangium oc...
EDM79842      614 HRAGEAFTLHVEVRNPGTETLEQVHLITDCARD-ELDGIELLIGALPPGESTSRDIEL---------------------- 670  Plesiocystis ...
WP_011555759  655 ILAGEVMEMALTAENRGTEPLKRVRAWTESDNA-FLDRREFLFGALAPGEKKTWKVKV---------------------- 711  Myxococcus xa...
WP_012098730  663 HRAGETVSWTVTVENKGDAPFRRLRAWTTAEKNaLLDRREFVFGNVPPGQRRSWTVPL---------------------- 720  Anaeromyxobac...
WP_012239069  606 VTAGQPMELRVTVKNNGKQPVYRLRGTTESDNP-YFDSKELIFGKIGPGQTKSAKAPLgwcdvegrkvgstkprkanekr 684  Sorangium cel...
EDM74020      666 --SVSAHELSRTDRIDFHlLSQHDAALTANsaTSIDVSAKGVDRPKFAYGYQVIDDpklaak--------------gnai 729  Plesiocystis ...
EEJ01102      637 --KLPDAAYDRVDRLDVE-FTEARGNAVAA--APVNLRVVAADRPVFAYSHQLVDE------------------------ 687  Haliangium oc...
EDM79842      671 --QVLPWYPDFVDTLTVA-AHVGEPEATPDgeASVAFTMLGAERPRFSFDYWIIDDphlvaegparpehepwpgevpfvv 747  Plesiocystis ...
WP_011555759  712 --RLPKDLTSRRDDVTVR-FFDDHGALPET--RVAELNFVELPRPAFAFNWQVIDDca---------------------- 764  Myxococcus xa...
WP_012098730  721 --KLPKGMDSRRDEITLH-FEEDGGHAPAD--LLTSVGVVEVAKPVFAFSVQIDDRq----------------------- 772  Anaeromyxobac...
WP_012239069  685 vcTIPMDALSRSDGLKVK-FEVAAAPEPPA--VEIRPTVRALDRPLFQYAYQIADDr----------------------- 738  Sorangium cel...
EDM74020      730 vGNGDGLLQVGERVHLRVWVQNAGPGDARD-TRVQLRNGSGDAVFLHSGRIKVGELKVGKADFVDIDFEVQK---PTDDV 805  Plesiocystis ...
EEJ01102      688 -SNGDGLVQIGETHHLRVTIKNTGKGTAKE-PTALLRNASGDGILLKKARFELDPLAPGESKTLDFVFDVKPe-lREDEV 764  Haliangium oc...
EDM79842      748 qGNGDGLLQPGEHVLLAFRAHNAG-GPAPD-ARVLLRNLSGTQGLLEEGLVVHGALAQGEEFTGAFGVSIAPtadPSQPL 825  Plesiocystis ...
WP_011555759  765 tCNGDGTVQRGETVSVLLDVTNAGTGTALD-SFTQIKNGGDANIFIEKGRFKLGELKPGETKTARFQLEVKKg-fKGNTF 842  Myxococcus xa...
WP_012098730  773 fGNGDGLAQRGETFDVRLDVRNAGTGAAGDkTWVSLKNLGDEKLFVKKGRESLGALKPGETKSARMEVELRRg-sKSDTL 851  Anaeromyxobac...
WP_012239069  739 eGNGDGLIQKGERVSMYLTVKNVGKGPSYE-TQANIANLSGDGLMLHAGRFDISNIKPGDVRKVVFSFDVEQq-lSEPEA 816  Sorangium cel...
EDM74020      806 SLQLTVSDAKIGEYLMDELSFPISAPLDFRGEGG-----VSASAQIDLYAGPYEGAPVLARAEAGASFATTGNA-GGWYE 879  Plesiocystis ...
EEJ01102      765 VVEMTVYDANLHVSVIEKLHYPVRVPSAGPTPAKgy--vQVARQEAAVLEGAAEDASRVASAPKGAVFQVTGRL-GDWYR 841  Haliangium oc...
EDM79842      826 ELELIVGDGVLRESVDDKLRFRIVPGRDAVSDAHsgrykVGGDEPVRLYNGADSSAPVVAELPAGTLLEVVGSS-GDWRA 904  Plesiocystis ...
WP_011555759  843 PLKLAIIDEPLEEFVMEKLELPVTDAAIATMEPKkg--lIRVGDKVDLYGAPAQGARAVAKLSGTTVLPAEAVT-KGYYR 919  Myxococcus xa...
WP_012098730  852 PIRVMIVDEKMEEYVSEKLDWPIAKDEQARTPASga--iRVEVAEATLRSGASAAAPAIATARRGALMPVDAKI-GEFFR 928  Anaeromyxobac...
WP_012239069  817 TLTLSVGDRDLREFASEKVKIPISPRIQLSGGGSt---mKAGAEGATLLPSPEASARGFGRLPAGAVVKVLGEApGGFLK 893  Sorangium cel...
EDM74020      880 LR--LGKDQVAYAKASALTS-EAKaprRPGATTTVYPVSPPRIELQDVPGQ--------TADTSITLSGVALDG------ 942  Plesiocystis ...
EEJ01102      842 VR--LDDKRPGFIASEDVRPtKSRa--KQSKLTTNWQVTPPAISVEIPAYV--------TQDATYRLSGSATDD------ 903  Haliangium oc...
EDM79842      905 LAgpKGQGRRLWVPADLLEAaSGGkarAALDPKAGRMVDPPHIVLADDAGEdgddgapvVETERVTIAGVAEHP------ 978  Plesiocystis ...
WP_011555759  920 VE--LEKDRFAFVRSQDAKElKTGkatTPKA-TLVTNHRPPDIRLDVDPAAgg----mvANGDKFTLSGVVTDP------ 986  Myxococcus xa...
WP_012098730  929 VE--WQKGRFAFVPDSEVRAaRGt---RSGTIAAAWQREPPRIALVPDPQRga----pvVEGDSWKLQGSALVPpsadpd 999  Anaeromyxobac...
WP_012239069  894 ID--LGAGRFAFVAARE-VApGGGpapAAVAFEDLYSHAPPTLDIA----Aaa----laTTAGTVKITGTASDS------ 956  Sorangium cel...
EDM74020      943 EAVRDVYVTVQnpsrnlfgsAEKISYVASK---DPSSGRLEFSAEVPLEPGNNYIEIVARENGQVSGRQRMWVLRT 1015 Plesiocystis paci...
EEJ01102      904 THVEDVYVFVSnrds--eveNRKVFYKSNRg--GGKPNELPFQAEIPLGLGTNQVTVVARENDEVKSTHTVYVYRS 975  Haliangium ochrac...
EDM79842      979 ERVRDVMVTVRaagp--aqpERKVFYLANRavdGDAAKRLEFSAEVPLSPGSNRVTIIVRDQDKVMRQRDLRVFRR 1052 Plesiocystis paci...
WP_011555759  987 HGLLDVYVLVN---------DQKVYFKGVDp-kGAEPNTLKFSTEFALKEGNNNVLVVAREDNDFASRRTLVIRRR 1052 Myxococcus xanthus
WP_012098730 1000 ARLRDVFVFVN---------EQKVFFKVLPe--DATTSKLDFSADIPLQAGNNVVTVFAREDDEFQSRRSIVVYRR 1064 Anaeromyxobacter ...
WP_012239069  957 ERLLDTFIFVG---------SRKLYYKSNRd--GADPKKAEFAFEAPLRPGVNVITVVARETPDTTTRRTLVVRKD 1021 Sorangium cellulosum
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