Conserved Protein Domain Family
PLP_synth_Pdx2

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TIGR03800: PLP_synth_Pdx2 
pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2
Pyridoxal 5'-phosphate (PLP) is synthesized by the PdxA/PdxJ pathway in some species (mostly within the gamma subdivision of the proteobacteria) and by the Pdx1/Pdx2 pathway in most other organisms. This family describes Pdx2, the glutaminase subunit of the PLP synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine]
Statistics
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PSSM-Id: 274792
Aligned: 6 rows
Threshold Bit Score: 295.494
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010988229   5 VIGVLALQGDVREHL----IALAAADAVAREV--RRPEELAE----VDGLVIPGGESTTISKLAHLFGMMEPLRARVRGG 74  Streptomyces av...
WP_002026805   9 KIGVLGLQGAVREHV----KSVEASGAEAVVV--KRIEQLEE----IDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSG 78  Bacillus cereus
WP_001849526   2 KIGILALQGAFAEHA----KVLDQLGVESVEL--RNLDDFQQdqsdLSGLILPGGESTTMGKLLRDQNMLLPIREAILSG 75  Streptococcus p...
WP_011082818   2 KIGVLALQGAVREHI----RHIELSGYEGIAI--KRVEQLDE----IDGLILPGGESTTLRRLMDLYGFKEKLQQL---D 68  Staphylococcus ...
WP_003019423   7 KVGVLAIQGGYQKHA----DMFKSLGVEVKLV--KFNNDFDS----IDRLVIPGGESTTLLNLLNKHQIFDKLYNFC-SS 75  Francisella tul...
WP_011012675   3 KIGVIGLQGDVSEHIeatkRALERLGIEGSVIwvKRPEQLNQ----IDGVIIPGGESTTISRLMQRTGLFDPLKKMIEDG 78  Pyrococcus furi...
WP_010988229  75 MPVYGTCAGMIMLADKILDPRSGQetIGGIDMIVRRNAFGRQNESFEATVDVKGVGGDpVEGVFIRAPWVESV-GAEAEV 153 Streptomyces av...
WP_002026805  79 KPMFGTCAGMILLAKTLIGYDEAH--IGAMDITVERNAFGRQKDSFEAALSIKGVGED-FVGVFIRAPYVVNV-ADNVEV 154 Bacillus cereus
WP_001849526  76 LPVFGTCAGLILLAKEITSQKESH--LGTMDMVVERNAYGRQLGSFYTEAECKGVGKIpMT--FIRGPIISSV-GEGVEI 150 Streptococcus p...
WP_011082818  69 LPMFGTCAGLIVLAKNV-ENESGY--LNKLDITVERNSFGRQVDSFESELDIKGIAND-IEGVFIRAPHIAKV-DNGVEI 143 Staphylococcus ...
WP_003019423  76 KPVFGTCAGSIILSKG-----EGY--LNLLDLEVQRNAYGRQVDSFVADI---SFNDKnITGVFIRAPKFIVV-GNQVDI 144 Francisella tul...
WP_011012675  79 LPAMGTCAGLIMLAKEVIGATPEQkfLEVLDVKVNRNAYGRQVDSFEAPVKL-AFDDKpFIGVFIRAPRIVELlSDKVKP 157 Pyrococcus furi...
WP_010988229 154 LAEHGGHIVAVRQGNALATSFHPELTGDHRVHGLFVD 190 Streptomyces avermitilis
WP_002026805 155 LSTHGDRMVAVRQGPFLAASFHPELTDDHRVTAYFVE 191 Bacillus cereus
WP_001849526 151 LATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFIN 187 Streptococcus pneumoniae
WP_011082818 144 LSKVGGKIVAVKQGQYLGVSFHPELTDDYRITKYFIE 180 Staphylococcus epidermidis
WP_003019423 145 LSKYQNSPVLLRQANILVSSFHPELTQDPTVHEYFLA 181 Francisella tularensis
WP_011012675 158 LAWLEDRVVGVEQGNVIGLEFHPELTDDTRIHEYFLK 194 Pyrococcus furiosus
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