Conserved Protein Domain Family
RNP_Burkhold

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TIGR03795: RNP_Burkhold 
ribosomal natural product, two-chain TOMM family
Members of this protein family are found sparsely, mostly in members of the genus Burkholderia. Members often occur as tandem homologous genes, such as BMA_0021 and BMA_0022 in Burkholderia mallei ATCC 23344, or else have a duplication. The genes regularly are encoded near a cyclodehydrogenase/docking protein fusion protein of TOMM (thiazole/oxazole-modified microcins) biosynthetic clusters, suggesting a role in bacteriocin biosynthesis. The role of the putative natural product is unknown, but function as a two-chain bacteriocin is suggested. [Cellular processes, Biosynthesis of natural products]
Statistics
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PSSM-Id: 163507
View PSSM: TIGR03795
Aligned: 6 rows
Threshold Bit Score: 134.917
Threshold Setting Gi: 556603849
Created: 9-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011796141  135 GGALPTglgipggdPGSLLAFGGVVLRAIALAWQSKEFRDELLnpgcADAAPLLSQWLGYNNPFNFSIRFTPNKSLTWDA 214  Acidovorax ci...
WP_004189426    4 NNAVPT--------HQSLLDFPEVYLRAIALSWENEQFKRELL----ADPLDALERYFDYRCPWILNLKVAEVPPDESHY 71   pseudomallei ...
WP_006480160    4 DNANPT--------LESMLEFQKVYLRAIALSWRDPAFKAELL----DRPLDTLAKYFGYQCPWIIDIDIEKTGGD---H 68   Burkholderia ...
WP_011548729    4 DLRLPT--------YEQFLEYRATVIRAIALAWHSPAFLDKLE----ADPVHALREQFDYHFPFKLDLKVQLKSSEWTPT 71   Burkholderia ...
WP_009893002    4 NNAVPT--------QQSLLEFQEIYLRAIALAWENEEFKRKLL----ADPHDALERYLDYRCPWILNLKIVEAPANEPAY 71   Burkholderia ...
WP_023360148 1364 SPNVPT--------YDQFLEYRAVIVQAIAAAWHDAEFREELI----AHPVDALHKRFDYRFPMKMHLKVHENSATWTPL 1431 Burkholderia ...
WP_011796141  215 GKGCWNQlnpDGSKIKNRIVLNYPNAPEARDFWPISLTSYNNTGSAYP 262  Acidovorax citrulli
WP_004189426   72 GWDAKRQ---RWNLPVNTLRVGIPTPPKHLAEEGIALAAYNDAGPAYL 116  pseudomallei group
WP_006480160   69 GWTSDGKgggSWNLPRNVMTVGIPEQPTHLDEEAVALAAYCDAGPCYL 116  Burkholderia cenocepacia
WP_011548729   72 VNGDWTAg------QKNRLTLYLPPAPVDDAQFAQALAAYNADHITIM 113  Burkholderia cenocepacia
WP_009893002   72 GWNAEKQ---RWYLPVNSLSVGIPAQPANLAEEAIALAAYNDAGPAYL 116  Burkholderia thailandensis
WP_023360148 1432 TNGGWTTn------EVNGLDLVLPPAPPPE-QRAAALAAYNARHISLF 1472 Burkholderia pseudomallei
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