Conserved Protein Domain Family
P_ac_wall_RPT

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TIGR03769: P_ac_wall_RPT 
actinobacterial surface-anchored protein domain
This model describes a repeat domain that one to three times in Actinobacterial proteins, some of which have LPXTG-type sortase recognition motifs for covalent attachment to the Gram-positive cell wall. Where it occurs with duplication in an LPXTG-anchored protein, it tends to be adjacent to the substrate-binding protein of the gene trio of an ABC transporter system, where that substrate-binding protein has a single copy of this same domain. This arrangement suggests a substrate-binding relay system, with the LPXTG protein acting as a substrate receptor.
Statistics
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PSSM-Id: 274775
Aligned: 32 rows
Threshold Bit Score: 48.4997
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011274185  223 AHTHMSWSFSKPGTYTLHLSASLVPDEG--KppEHIADQTVRFTV 265  Corynebacterium jeikeium
GAE75196       80 AHTHMSWAFSKPGVYKAVFAATLSTPQG--N--ASFGAQTLTIAV 120  Propionibacterium acnes JCM 18918
WP_028564638  214 AHTHMSWAFTKPGIYRLSMRAQLSVDPQapS--VPMGEQVFTFAV 256  Salinispora tropica
WP_011274181  262 GHGHFGWTFSKPGLYQLTMQWDVKKKDGs-T--VKSAERTINWLV 303  Corynebacterium jeikeium
WP_014303706  183 NHTHNQTTYTKPGQYEVTYRASARTTDG--Tl-IESKPQKLVWQV 224  Corynebacterium diphtheriae
WP_014319569  218 rHSHYHTTFTKPGRYVFTYQATAYDSEG--Ep-IKTMPMNLAWQV 259  Corynebacterium diphtheriae
WP_016829979  238 SHGHFNWTFSKPGIYELTWEA--YVKNGafK--VKTEPVRQIWLV 278  Corynebacterium diphtheriae
WP_021335293  709 LHLHGNWSFNKPGQYTLYFKATS----G--Dk-eIAAPQPVTFLV 746  Corynebacterium diphtheriae
WP_014302189  955 FHSHLDWIFTKAGTYKIQMRAVNDKd--------ATDWTTITFDV 991  Corynebacterium diphtheriae
WP_004566665  187 AHTHVSWSFSKPGMYHLTFAAKV---KG--K---LVARNTINVAV 223  Corynebacterium diphtheriae
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