Conserved Protein Domain Family
blh_monoox
?
TIGR03753: blh_monoox 
beta-carotene 15,15'-monooxygenase, Brp/Blh family
This integral membrane protein family includes Brp (bacterio-opsin related protein) and Blh (Brp-like protein). Bacteriorhodopsin is a light-driven proton pump with a covalently bound retinal cofactor that appears to be derived beta-carotene. Blh has been shown to cleave beta-carotene to product two all-trans retinal molecules. Mammalian enzymes with similar enzymatic function are not multiple membrane spanning proteins and are not homologous.
Links
?
Statistics
?
PSSM-Id: 274766
Aligned: 51 rows
Threshold Bit Score: 74.9908
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
ABL97831                                 56 LPLYLSLFLFGMPHGGADHLLIWGMir-kSTWLFRVSTLLLYPTLSIFYLICWHFQPVASAIFFLVITIFHWGQGDRYLS 134 uncultured marine bacterium HF10_49E08...
ZP_01734913                              29 FLGFLLIFTFGILHGANDLVLISQLe--nRKKQNFLKILISYIIVVLISVLLFTKIPIVALILFILVSAYHFGEQHWEEI 106 Flavobacteria bacterium BAL38...
ZP_03701023                              30 YTAYFCILSLGILHGANDLGIGKKTlhahAFISKKWILLLIYVLAIFSVAFLLMQFPTMTLTLFVLFSAYHFGEQHWESL 109 Flavobacteria bacterium MS024-3C...
ZP_01253359                              21 VIALLGIFSLGILHGSNDLFVIENLns-nSQKPNFYKSLFAYLGVVLSFVAVFYFIPIFAIAAFVIISSYHFGEQHFHHK 99  Psychroflexus torquis ATCC 700755...
REF_WGS:AANA:1099517003557_MED152_12849  34 YIGYVLVISIGILHGANDLLILSIRq---KVKILDKKNLITYLGIVFICFLLFYIQPFFSICLFILISSYHFGEEHFSRN 110 Polaribacter sp. MED152...
ZP_01117886                              34 FIAYVMVVSIGILHGANDLLILSKKd---KGKRTFIKNLIIYIGIIGFCLIIYIFNPFVAILLFVFLSAYHFGEEHLGVR 110 Polaribacter irgensii 23-P...
ZP_01049272                              26 IIAYVAIFTLGLVHGANDIKLLEKNv--sSSPNHKYVILGRYLLIVVAIAILFYVIPSLALILFILVSGFHFGEEHWDKL 103 Dokdonia donghaensis MED134...
ZP_03702118                              43 LIAGIGILSFGILHGANDLKIIAKSrv-kTKSKNSFNYLALYITIVFLGIVIFYFIPGIALLSFVVVSCYHFGEQHWEER 121 Flavobacteria bacterium MS024-2A...
ZP_01449289                              40 FIMICSIMVLGVPHGALDYSLAVNGlg-lVSISRKIQFLLFYLAIVLLSIGLWLLSPISGFLLFMFMSVWHFS-EDWSF- 116 Rhodobacterales bacterium HTCC2255...
WP_011281488                             39 iiclllilsigisHGALDNQKGKRLik-lYNINNIYYFYLIYLIIAATIIIIWLLAPTLSLIIFLVVAAYHFGKEDTEFL 117 Candidatus Pelagibacter ubique...

ABL97831                                135 VklhracyleRSNLLKILHITARGSIPILLPGYLGN--ETYRMFLEEMIRQGgqidydLSW-----VSENQLFFLLVPLS 207 uncultured marine bacterium HF10_49E08...
ZP_01734913                             107 Ik-------dGNNLIKKIFQFNYGLIILLLLFYFNK--QEVIEIVFKITAFA--------I-----NEITISIVFLIALV 164 Flavobacteria bacterium BAL38...
ZP_03701023                             110 Is--------NKGVFAKMFMTAYGMSIFTLLFSAHS--LLVSDIIQDISNVR--------L-----SPTLIQMSMYASLA 166 Flavobacteria bacterium MS024-3C...
ZP_01253359                             100 Lq-------nTQSFWSSLFFLFYGLLVLFLILSLNS--KEVILIVQDMTGLL--------I-----DSQFLNIVLFISAL 157 Psychroflexus torquis ATCC 700755...
REF_WGS:AANA:1099517003557_MED152_12849 111 Is--------VNWWFDTFFYTTYGILLFAILFTFAL--DNVKEIMVELTGNY--------F-----NNNEVTITLITSGV 167 Polaribacter sp. MED152...
ZP_01117886                             111 Is--------VNATFDFTYFLAYGLFI--FSLLLHQsiPDVDKVMRELTGTI-------IT-----VKQIEIVLITSASV 168 Polaribacter irgensii 23-P...
ZP_01049272                             104 Iv--------TKGNGHYLFYTAYGLLILFLIFYFNS--EETTEIISAITGFT--------------PAKFYYLVGLIFFA 159 Dokdonia donghaensis MED134...
ZP_03702118                             122 L---------KFNKWDSLYYFTYGALIFLMLFTFHY--EDTTEIIFQITSLR-----------------PPFLIFLIILI 173 Flavobacteria bacterium MS024-2A...
ZP_01449289                             117 ----------DVGDRRHCAIAVWL---ITMPALFKP--NEFNDILSVLWLTT--------G-----QIEIVTIASQFGAI 168 Rhodobacterales bacterium HTCC2255...
WP_011281488                            118 It--------KKSNIDIILYFLKGILIIIAPLMFHF--VETINIFKLLLIQN------ESFylflnFIENNYIISFIFLI 181 Candidatus Pelagibacter ubique...

ABL97831                                208 LMVMQLFVSIFQlekdervAWGL--D-LSEACFLFLWFLFLPPLWALGIYFALWHSLRHGLRIIWLDptgkQSLVAGAYL 284 uncultured marine bacterium HF10_49E08...
ZP_01734913                             165 LFLINTYIMYKNsa---sfKKIVieQ-LFYLMLLCLIFKVSGLIWGFTIYFIFWHSIPSLNDQIRFL----YGNYSFINF 236 Flavobacteria bacterium BAL38...
ZP_03701023                             167 ITAILYAIKYQKtf---eySFTL--RqIFYLLVFFVVFNSTTLLWAFAIYFIFWHSLPSLVDQMNFL----YGRTDFKGF 237 Flavobacteria bacterium MS024-3C...
ZP_01253359                             158 GSIGLFIFLSKTnp---klKSSLfpN-VIYLILFMALFAVSNVVWGFASYFVLWHSIPSLKDQVNSL----YGTFNFENF 229 Psychroflexus torquis ATCC 700755...
REF_WGS:AANA:1099517003557_MED152_12849 168 LFLLLNVFLIIKkki--nlSNFL--KeLFYLALIAVVFNTSSLILGFAIYFILWHSIPSILGQIEFI----SGDFNKKNI 239 Polaribacter sp. MED152...
ZP_01117886                             169 LFLGSVYLFLSKrv---alGVFV--KeSFYLLLLFLVFKTSSLILGFAIYFILWHSIPSIMHQIEFI----SGDLNKANV 239 Polaribacter irgensii 23-P...
ZP_01049272                             160 ILSILSFIVAKAqm---ntTSTIlqE-IVHLIILAIVFKMATLLLSFALYFVVWHAIPSMKSQIIYL----YGNTSQKSI 231 Dokdonia donghaensis MED134...
ZP_03702118                             174 VISIAVFIQFFIrl---dsKSTIikE-TFLLGLLALLFFRGTLLFGFGMYFVVWHSFPSLRSQVNYI----YDTFDKKTF 245 Flavobacteria bacterium MS024-2A...
ZP_01449289                             169 AASAFVLFGYKRe------NIVL----YLELIALLIILTQGGILQYFTAYFCIIHSPLYVRRFVIK---------VPMKR 229 Rhodobacterales bacterium HTCC2255...
WP_011281488                            182 SLLTNIYFFLKDfk---lvNLLI----FFDFTSILILNYFFTPLVAFTLYFCFLHSFRHSLSLITEL----DKYNFKNGL 250 Candidatus Pelagibacter ubique...

ABL97831                                285 KLKARWLQISGlmtILALVGLWFLLALPLsfrgiqLDWLGKAMLGISILTLPHTVVVC 342 uncultured...
ZP_01734913                             237 KKYFKSAFLYWiisLVGISLLYLISKDMI-------IFDALFFSFLASITFPHAIVIL 287 Flavobacte...
ZP_03701023                             238 VMFVKSSWLYWamaVLSLGAYYFILKQYL------VLELSMFFAFLTALTMPHIFLMY 289 Flavobacte...
ZP_01253359                             230 LSYFKKAFPYWlasIIGMLVVVWLFKDSK-------NFLSLLFAFIAAITFPHVFIMR 280 Psychrofle...
REF_WGS:AANA:1099517003557_MED152_12849 240 LFYLKKGAIFWgfsILGLLLLYVIFIDVK-------ILNSLIFMILFAVTAPHIWVMN 290 Polaribact...
ZP_01117886                             240 LYYFKKALLYWgisIVSLFILYQIVSDIE-------LFSTVIFAILFAVTAPHAWVMF 290 Polaribact...
ZP_01049272                             232 VGYLRSSLAYWllaITSISIFYYYLGDKT------YLFNAIFFAFLAAITFPHVWIIN 283 Dokdonia d...
ZP_03702118                             246 LKYLKSAFIYWiiaLLGLFGAYFFLNIPS------DQYLQLFFSFLAAITFPHAIVME 297 Flavobacte...
ZP_01449289                             230 IEMLFQLMAIMiatVMLLSALWWLSDVYQi----dVGIYAWLFIGLFALTVPHMLLVE 283 Rhodobacte...
WP_011281488                            251 LIFIKKAAPLTiltAIFYLLSLYYLSNHYlv---nEAIYKVIFIGLASLTFPHILLEY 305 Candidatus...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap