Conserved Protein Domain Family
menaquin_MqnC

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TIGR03699: menaquin_MqnC 
dehypoxanthine futalosine cyclase
members of this protein family are involved in menaquinone biosynthesis by an alternate pathway via futalosine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Statistics
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PSSM-Id: 274731
Aligned: 20 rows
Threshold Bit Score: 494.464
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011194951  40 HRISYEEGCVLMREGDLGSLGLVAGEITRRFHPDNIVTFVVDRNINYTSVCVTDCKFCAFYRHEKDPDAWVLSHEEILQK 119 Symbiobacterium...
WP_011577737   1 MRINREEMLDLMKNAPLKELGQRALRVKQRLHPENLTTFIVDRNINYTNICFVDCKFCAFKRTLKEKDAYVLSYEEIDQK 80  Helicobacter ac...
WP_011119748  22 DRLTSAEGLTLLESHDLAAIGAAAEKVSRAKHSEPYRTYNIDRNINYTNVCTAVCDFCAFYRGPKSEEGYVLPREVLLQK 101 Rhodopirellula ...
WP_010899286  14 ERLSMEDAVKLYESDEVEKMGAAANQIMLKWHPEPITTFVIGRNVNYTNFCDTYCRFCAFYRAPGHKEGYVLDDEVILKK 93  Bacillus halodu...
WP_011602252  21 GRISPEEALLLYTRAPLHALGTAADTVRRRRYPDGIATYIIDRNINYTNICVTACRFCAFYRAPKHAEGWVRDVDDLVTK 100 Frankia alni
WP_010883546   5 KRISFEEGLELFVSSPIERLQERADAIRKERYPSNEVTYVLDANPNYTNICKIDCTFCAFYRKPKSPDAYLLSFDEVRSL 84  Chlamydia pneum...
WP_011763062   2 plFKRDDIEELLK-ADLWELGRRAYEIRLRTY-GKTTTFISNMVLNYTNVCVVGCSFCAFYRPPGHPESYVYTVEEAVKR 79  Pyrobaculum isl...
WP_000146501  21 NRISPEEALALYREGDHLKIMATARSLREKILPHHYASYTMFRVVNYTNYCNVECSFCSFMDEIGNGKGYVLSVEEILEK 100 Leptospira inte...
WP_011007766  13 RGLDRSDAVFLMKEADVFTLAKVADELTRKYF-GDVVTFVNNVVINYSNICVAKCPICAFYRLPGHKEGYLRSPEEVAAM 91  Pyrobaculum aer...
WP_010917637  18 EDLDEDDIVYMYDEADVNDLGKLARSITDKI-SGKRVSFVSNIILNYTNICNVRCKFCAFYRKSGEYDAYTMTPDGVIDE 96  Thermoplasma vo...
WP_011194951 120 VGEL-AATGGTQVLIQGGHHPKLPFAYYTEMCRLIKRHYPQVAIHSFSVSEIRHFARAYKMPVREVIERLKEAGLDSVPG 198 Symbiobacterium...
WP_011577737  81 IEEL-LAIGGTQILFQGGVHPQLKIDYYENLVSHIAQKFPTITIHGFSAVEIDYISKISKLSLKEVLERLKNAGLSSIPG 159 Helicobacter ac...
WP_011119748 102 IQET-VDLGGNQILLQGGLHPKYKLDWYEEMLRDIKSRFPEVNVHGFSPPELHHFTKVNNLPLRDVLSRLKDAGLGSVPG 180 Rhodopirellula ...
WP_010899286  94 IQET-IDVGGTEILMQGGTNPDLTIDYYTDLLRNIKERFPNIWMHSFSPAEVWKIAEVSSMSVEEVLRELHEAGLDSMPG 172 Bacillus halodu...
WP_011602252 101 CGEA-VELGATQIMLQGGHNPDFGIEWYEQVFGAIKAAYPQLALHSLGASEVVHIARTSGLTFPEVITRLRDAGLDSFAG 179 Frankia alni
WP_010883546  85 LQRY-VSSGVKTVLLQGGVHPGLGIDYLEELVRITVQEFPSIHPHFFSAVEIEHACRVSGISIEQGLQRLWDAGQRTIPG 163 Chlamydia pneum...
WP_011763062  80 VLAIdAKYGIRQVLIQGGVNPDVGIEYFEALFRAIKTKAPHIAIHALSPLEIDYLSRRERATYREVLERLREAGMDSMPG 159 Pyrobaculum isl...
WP_000146501 101 MDYA-VGEGADQMFLQGGVYPDLSFDYYLNVISAVKKKYPHMHIRAFSPVEIINLEKITGLPLKEVLQILKQTGLDSVPG 179 Leptospira inte...
WP_011007766  92 VEFFhRQYGVTELHINGGFNPFIAPEYFDELFRAVKKRAPHITIKGPTMAEVDYYARLWKTSWREVLSRWKEAGLDAISG 171 Pyrobaculum aer...
WP_010917637  97 IRKY-YPYGIRQILIQGGVNPNLDLDYYLTVFRKIRENFTEAGINGLSAAEINFISKKAHLTYEETILKLKEAGLETIPG 175 Thermoplasma vo...
WP_011194951 199 AGGEVLADRPRRIIAPLKDPARDWLETYELIADCGLRGSSTMMFGHVETLEERVEHLLRLREVQDRTaekhgvGVFWSFI 278 Symbiobacterium...
WP_011577737 160 AGAEILSDRVRDVIAPKKLSSDRWIEVHKTAHLCGIKSTATMMFGSVDNEEDVMEHLQRVRDLQDET------GGFRAFI 233 Helicobacter ac...
WP_011119748 181 GGAEILTDRVRNEITRGKVMTDDWLNVMRVWHELGGISSSTMMFGHVETLAERIEHLERLRSLQDET------GGFTAFI 254 Rhodopirellula ...
WP_010899286 173 GGAEILTEETRLRVSRLKITWEQWINAMKATKKVGMHGTATMVIGFGESFEERALHLQRVRDAQDET------ECFTAFI 246 Bacillus halodu...
WP_011602252 180 AGAEILTERPRHAIAPLKEPGHVWLSVMETAHTLGLESTATFMMGTGETNAERIEHLKMIRDVQDRT------GGFRSFI 253 Frankia alni
WP_010883546 164 GGAEILSERVRKIISPKKMQPGGWINLHKLAHLMGFRTTATMMFGHVENPEDILIHLQTLRDAQDSC------PGFYSFI 237 Chlamydia pneum...
WP_011763062 160 GGGEILVDRVRKEVAPRKIDSSTWLRIMEEAHKIGIPTSATMMYGHVETISDIAEHMYKIAELQEKT------KGFLAFI 233 Pyrobaculum isl...
WP_000146501 180 AGAEILTDRMRNIISPKKATTEEWVRAMETCHEVGLPGSANIVFGSEETQEEVIEHLNVVRNLQDRT------GGFLSFI 253 Leptospira inte...
WP_011007766 172 GGAEIFAEEVRRIISPHKISGEEWVKIAEVAHEMGIPSNATMLYGHVERVEHVVDHLFRIKELQERT------GGLMLFI 245 Pyrobaculum aer...
WP_010917637 176 AGAEILDEDVRVKLGRPRGSGRQWLEIMETAHRLGVKTTATMVYGHIESSMDKARHLISIRNLQKKY------HGFLSFT 249 Thermoplasma vo...
WP_011194951 279 CWTFQPGNTPlvaegLHN----G----VA--TSSYEYLRTLAVARIFLD-N-IPNIQASWVTQGVRIGQISLDCGCNDFG 346 Symbiobacterium...
WP_011577737 234 LWSFQPNNTP-----LKEeipsI----KK--ASSNRYLRYLACSRIFLD-N-IQNIQSSWVTQGSMIGQLALLFGANDLG 300 Helicobacter ac...
WP_011119748 255 CWTFQPDNTE-----MSD----V----RP--TGSFEYLKMLAVSRLFLD-N-IPNLQSSWVTQGLKIGQMALMFGANDMG 317 Rhodopirellula ...
WP_010899286 247 SWLFQPENTG-----MYK----T----KK--LTPRDYLKNVAISRLFLD-N-IPNFQSSWVTMGPEVGKLSLQYGCNDFG 309 Bacillus halodu...
WP_011602252 254 PWTYQPENNH-----LGG----R----TQ--ATTLEYLRLVAVARLFFD-N-IAHLQGSWLTTGKEVGQLTLHMGADDLG 316 Frankia alni
WP_010883546 238 PWSYKPGNTA-----LRR----N----VPqqASIETYYRILALGRIFLD-N-FDHVAASWFGEGKSLGAKALHYGADDFG 302 Chlamydia pneum...
WP_011763062 234 AWNFEPGTSE-----LGKr--iK----YP--KTSATLLRIIAVARIVFD-GiIPHIQSGWLTTGPETAQLAMYFGADDFG 299 Pyrobaculum isl...
WP_000146501 254 PWTFQPQTKR-----F-K----V----RA--VPTQEYLKVLGICRIFLD-N-ILHIETSVMVLGKGVGQLALTSGADDIS 315 Leptospira inte...
WP_011007766 246 PVKFNPLNTE-----LAA----RgvvaRP--APSTYDVKVVAIARLILK-D-RLKVGAYWLSVGKKLASTLLLSGANDLV 312 Pyrobaculum aer...
WP_010917637 250 PWNMEPDNTE-----LQKegilK----YR--AGAEDVIRNIAISRIVFNyD-LPIIQSSWLTNGVEMGQLAILYGANDWG 317 Thermoplasma vo...
WP_011194951 347 GTMMEENVVAAAGTIYHAT-PAD-AIRLIRDAGKIPARRNTFYEIL 390 Symbiobacterium thermophilum
WP_011577737 301 SVMMEENVVKAAGTSFCMN-EAE-MIGLIEDIGSVAVKRNTAYEIL 344 Helicobacter acinonychis
WP_011119748 318 SLMIEENVVAEAGTVHYLS-LQQ-IREAIEELGFVPRQRDVHYNLV 361 Rhodopirellula baltica
WP_010899286 310 STMIEENVVSAAGTTHKVN-TNK-ILQLIREAGKIPAQRTTSYEII 353 Bacillus halodurans
WP_011602252 317 SVMLEENVVSSAGARHRTN-RSE-LISLIRTAGRIPAQRDTLYRHL 360 Frankia alni
WP_010883546 303 GVILDESVHKATGWSIQSS-EEE-ICNIIRSEGFIPVERNTFYQHI 346 Chlamydia pneumoniae
WP_011763062 300 GTLYEEKVLEWKRVETPIDkRED-VIQIIRSASFTPAERDNMYNVV 344 Pyrobaculum islandicum
WP_000146501 316 SVVIEENVLRSYGLKT----EKE-AVKFLKEGGFTPKRRDLLYNYD 356 Leptospira interrogans
WP_011007766 313 GTMYNEAVLTSAGAQHNAT-AEE-LAAIAREAGRRPALRDTFHRIL 356 Pyrobaculum aerophilum
WP_010917637 318 GTIYDEKVIPATGKRVGNL-RKEiIIRSIKDLGMVPVERDNLYREI 362 Thermoplasma volcanium
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