Conserved Protein Domain Family
Rv0121_F420

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TIGR03668: Rv0121_F420 
PPOX class probable F420-dependent enzyme, Rv0121 family
A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 132707
View PSSM: TIGR03668
Aligned: 7 rows
Threshold Bit Score: 179.649
Threshold Setting Gi: 499883224
Created: 9-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ETB06484       2 GEFDARARFGRASVARLATVSPGGQPHLVPVVFALAQGPDAD--HDAdpdVVYTAVDAKPKTT-RR-LRRLA--NIDANP 75  Mycobacterium a...
WP_003897940   2 AEFDAVTAFADAPAAVLSTLNADGAPHLVPVVFAVHVPHVEG--QPA---RIYTAVDAKRKTT-RN-LRRLA--NIDRDS 72  Mycobacterium s...
WP_003917886   2 GEFDPKLRFAQSPVARLATSTPDGTPHLVPVVFALGARRPAEatGAD---VIYTAVDAKRKTT-QR-LRRLA--NLEHNP 74  Mycobacterium t...
WP_011437068  26 TDVEARTRFTAARVARLATAGGDGRPHIVPVTFAVNAGAVNA--GAA---SVVTAVDHKPKSTlGG-LRRLR--NITENP 97  Frankia sp. CcI3
WP_012643102   5 LPPLVRTFLEQQRVGHLATVSRGGEPHVVPVCYVVA---------DD---TIYTPIDEKPKQP-GRtLRRVR--NIEETG 69  Thermomicrobium...
WP_010988878   5 DEDEARRRFMAARVARLATVDTEGRPHLVPVVFARH---------GA---EVVTAVDWKPKRS-PR-LKRLR--NIAAHP 68  Streptomyces av...
WP_011563958   2 LSPEEAAFLAGRRVARLATSSSRGEPHVVPVCFACG---------SG---GLYVPLDDKPKRV-PP-RRLRRvrNILENP 67  Rubrobacter xyl...
ETB06484      76 QVSLLADHYADDWTRLWWVRADGLATIHRDGp-------ALDTGYRLLRAKYPQYQSVPLD-GPVIAIAVRRWSGWA 144 Mycobacterium aviu...
WP_003897940  73 RVSLLVDHYSDDWTQLWWVRADGVATTHHSGd-------EVATGYALLRAKYHQYERVSLD-GPVISVEVSRWASWQ 141 Mycobacterium smeg...
WP_003917886  75 RASVLVDSYADDWTQLWWVRADGVAAIHRDGe-------VMRAAYRLLRAKYTQYQSVPLN-GPVIAIAVQRWASRH 143 Mycobacterium tube...
WP_011437068  98 QVSLLVDAYDDDWSRLWWARADGEARIVRAGe------pGHAPAVELLIARYDQYQAAPPA-GPAIIVTVARWSGWA 167 Frankia sp. CcI3
WP_012643102  70 RAALVVDRYDEDWTQLGWVLLRGRAELLAPGs------pEQARAVELLRQRYPQYQAMRLEtQSMIALRIERVSVWG 140 Thermomicrobium ro...
WP_010988878  69 AVCLLVDAYDEDWDRLWWVRADGRARILPPDapeprvreEYAAVLAVLREKYAPYRQRPPG-GPVIAITVHRWHGWR 144 Streptomyces averm...
WP_011563958  68 RAALLADRYAEDWGRLAFVMVRGRAELLEPGg------eEHGAAVRLLRGKYHQYERRPIErSPVIVLRPERAASWG 138 Rubrobacter xylano...
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