Conserved Protein Domain Family
T1SS_rpt_143

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TIGR03660: T1SS_rpt_143 
T1SS-143 repeat domain
This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]
Statistics
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PSSM-Id: 132699
View PSSM: TIGR03660
Aligned: 24 rows
Threshold Bit Score: 122.777
Threshold Setting Gi: 499533582
Created: 9-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_031843931 1080 GSFDSVEGADTIVSYQLD-LSG-NPISG--VTSGGQAVMLVQTGVNNNN--YTYQGqT-------PDG--K-S--VFTLV 1141 Vibrio paraha...
WP_025542585  748 GQFEVTS-ADGIDSFVLD-LNS-NLLPA--LTSGGESIAITQDATASTSdaLVYVGkT-------AGG--D-T--IFTLT 810  Vibrio paraha...
WP_031843931  931 GHFNVVAGADEIVSYHVS-DLA-GAVAG--LQSNGQDVELRLVSEADGV--STYEAvI-------VGT--NtQ--IFTLT 993  Vibrio paraha...
WP_031843931  780 GHFDVVDGADSIVSFQLE-DLV-LPVAG--LTSAGQPLELVEYSNANGV--IEYRA-Y-------VQG--T-TdiVFKLT 842  Vibrio paraha...
WP_031843931  332 GKFVATEGADHIVEYHIV-DLN-TPVQG--LTSGGQSLILVEVSNSGGV--SVYEA-I-------IDGttT-P--AFRVT 394  Vibrio paraha...
WP_031843931  483 GTFDVTEGADQVTSIQLS-DLT-TPVST--LMSGGEAITLVLTSSTGGV--NVYQGiT-------VNS--QeV--VFELT 545  Vibrio paraha...
EMQ09751      357 GQFDTQLGSDQVASYQID-PSTaNPIAG--LTSQGDAVILGEPTLIDGN--RVYQA-T-------AGG--R-D--IFQLT 418  Vibrio choler...
WP_011220681 2343 GQITVDSGSDEVVDFKVDvDAF-NANNT--ITSAGNSVSLID----AGN--GLYQG-M-------ANG--N-V--VFEFQ 2400 Photobacteriu...
WP_012563183  569 GDLEVHWGADDGAARHILmATD-GLPSG--LTSDGVAIDYQTTVDAAGY--AVVMA-YkhggspnAAS--D-Q--VFSLT 637  Oligotropha c...
WP_006229289 7506 GQITVDSGSDEVTDFVIDvATF-NQQNAgvLMSDGQQITLSYNSN---N--GNYFG-K-------VGN--T-T--IFVIK 7566 Photobacteriu...
WP_031843931 1142 LN-A-DGT--YKFTLEGVLDHG--Vq-G---EDLLTLNLPVFATDVDGDTA-G-I-NLPVTITDDIPTIYDSS---I--- 1202 Vibrio paraha...
WP_025542585  811 LH-Q-DGR--YDFELSGALDHA--T--N---SDDLTINLPIVITDGDNDSV-N-A-TLPVTILDDKPTIEAIR---Pgsh 873  Vibrio paraha...
WP_031843931  994 LD-AkDNS--YQFELVGPVDHP--AglG---ENSLTLDIPISVTDFDGDTSaS-V-NLPITIVDDVPEIKTAT---P--- 1057 Vibrio paraha...
WP_031843931  843 LN-AgEDR--YQFELFAQLDHPngN--G---ENELVIDFPVNATDFDGDVS-NtI-SLPITVVDDVPSITGVDnssQ--- 909  Vibrio paraha...
WP_031843931  395 LDvS-DGS--YKFELLEPLDHP--TsnG---QNDIVINLPIAATDFDGDVS-N-TlTLPITVVDDVPTIDGLA---Qgse 461  Vibrio paraha...
WP_031843931  546 LN-AsNNS--YEFDLRKALDHP--D--Gn-qQNNIIIELPITVTDGDGDVS-P-VfTLPITVVDDVPVVTNID---R--- 609  Vibrio paraha...
EMQ09751      419 LN-A-DGS--YQFVLQGTLDHA--A--G---SDALTISLPIVAIDYDNDSS-A-PgNLNIEIQDDKPIIIGAE---Q--- 479  Vibrio choler...
WP_011220681 2401 LN-A-DGS--YEFEIKGPIDHS--Iq-G---KDSITIDIPVYAVDQDGDTSeN-V-DMSVDVLDDIPSVKDKN------- 2461 Photobacteriu...
WP_012563183  638 FS-E-DGSgtYTFRLLGNLDHA--E--N---SNSQELVFKVDAYDSDGDPV-T-Q-TFTVDVADDQPFAIGTI---Lt-- 700  Oligotropha c...
WP_006229289 7567 LS-N-SGK--YEFILKGNVDHE--E--GgltDDELIITLPIQAIDQDGDKS-N-TvNVPVTIKDDEPTATDVT---L--- 7630 Photobacteriu...
WP_031843931 1203 TRVEgqgtrtvqlfqdpvEGDLNY-GADGSE 1232 Vibrio parahaemolyticus
WP_025542585  874 LSID--------------EDDIPNkGSDGQG 890  Vibrio parahaemolyticus
WP_031843931 1058 LFLD--------------EDDLPS-GSELSK 1073 Vibrio parahaemolyticus
WP_031843931  910 LTID--------------EDDLPA-GSDTSG 925  Vibrio parahaemolyticus
WP_031843931  462 QTVD--------------EDDLPQ-GTDRAQ 477  Vibrio parahaemolyticus
WP_031843931  610 LQVH--------------EDDLPL-GSDETK 625  Vibrio parahaemolyticus
EMQ09751      480 LTVA--------------EQTLDT-GSIGGG 495  Vibrio cholerae O1 str. EC-0009
WP_011220681 2462 ITIT--------------EGDNSD-KVDVLN 2477 Photobacterium profundum
WP_012563183  701 RTVE--------------EEELQG-GNEDTR 716  Oligotropha carboxidovorans
WP_006229289 7631 NTVEgls--------ttsADVLTI-IGEGAD 7652 Photobacterium profundum
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