2AEU


Conserved Protein Domain Family
pyridox_MJ0158

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TIGR03576: pyridox_MJ0158 
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pyridoxal phosphate enzyme, MJ0158 family
Members of this archaeal protein family are pyridoxal phosphate enzymes of unknown function. Sequence similarity to SelA, a bacterial enzyme of selenocysteine biosynthesis, has led to some members being misannotated as functionally equivalent, but selenocysteine is made on tRNA in Archaea by a two-step process that does not involve a SelA homolog. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 213830
Aligned: 5 rows
Threshold Bit Score: 480.799
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2AEU_A         5 YEEFLRLEKARKIILEILNEKGRDALYDLSGLSGGFLIDEKDKALLNTYIGSSYFAEKVNEYGLKHLGGde-nDKCVGFN 83  Methanocaldococ...
WP_011169946   4 LLELNRVNTAREIIRKKIQNTGRNSIYDLTGLCGGFEICEENLKLIETYVGPAIFSEKLNNAGLSHLSGnskiHNAVCFN 83  Methanococcus m...
WP_010877510   6 VNEVKRREHALRIIGEKMKKHGRDGIYDLTGLSGGFPLEEEDLDLIETYVGPAIFEEKLQEAGREHMGG----EMIAAFN 81  Methanothermoba...
WP_011406503   5 LNEVKRREKGLKIIKDKIETDGIDSLIDLTGLAGGFDITPEDISLLETYAGPAVYEQKVQKLGIKHLGG----EKILPVN 80  Methanosphaera ...
WP_011018990  12 VRSMKVRDRALEIIRERISRG--DPLYDFTGLASRPKVDAASDEL-RTYLSEALILPEIRELCREHFDAp--eYEVLVAP 86  Methanopyrus ka...
2AEU_A        84 RTSSAILATILALKP--KKVIHYLPELP-GHPSIERSCKIVNAKYFESDKVGEiLNKIDKDTLVIITGSTMDLKVIELEN 160 Methanocaldococ...
WP_011169946  84 RTSSAILSTIMTLSKsfEKLVHYVPEKP-AHPSIPRSCKIFGMEYFESDSLEEiLSKIDENSFTAITGATMDHKVVSEEI 162 Methanococcus m...
WP_010877510  82 RTSSAILAAVLALTEpgSTVFHYLPELP-SHPSVPGSTELASAGYQETEDFTE--KPPADTSLVVVTGSTMDHRVVGESD 158 Methanothermoba...
WP_011406503  81 RTTSGIVAMIIALVKpgTKIVHFLAKKP-AHPSIPRTAKLVGADYEEYTNLDE-FKIDDNTSLVFITGTTMDLEVISVED 158 Methanosphaera ...
WP_011018990  87 RTTAAVIATILALEP--RSVLHVLPEDGeAHPCVEEGCRLAGAE-YEEVEESE-IPDLDGFDLVVVTGCDVRWNVVSEDT 162 Methanopyrus ka...
2AEU_A       161 FKKVINTAKNKEAIVFVDDASGARVR-L-LFNQPPALKLGADLVVTSTDKLMEGPRGGLLAGKKELVDKIYIEGTKFGLE 238 Methanocaldococ...
WP_011169946 163 ACKIIDYAKSKNSPVFFDDASGARLR-K-LYKESPALEMGADLVVTSMDKLMDGPRAGLLAGDKNLVDKIYSEGLKFGLE 240 Methanococcus m...
WP_010877510 159 LVRVIEIAHDAGIPVLVDDASGARLRtV-LYGQRRACDLGADLAVTSTDKLMHGPRGGLMAGRAELIERVKSKAYQFGLE 237 Methanothermoba...
WP_011406503 159 FKRVIKQAKEKDVIVAVDDASGARIR-RaVYNQPTAIDLGADISVTSTDKLMEGPRGGLMAGSTEIIDKIKLVVNQYGLE 237 Methanosphaera ...
WP_011018990 163 LREVA----SAEAVTLLDDASGDRVR-R-LHGQKPGPRYGFDLVVTSCDKLMDGPRAGVLIGRDDLVEGVRRVCEGYGWT 236 Methanopyrus ka...
2AEU_A       239 AQPPLLAGIYRALKNFNLERIRKAFERAKNFDLSKI--EK-LNkelkaiddninivYERTPTGFVIKRVY-----KDdti 310 Methanocaldococ...
WP_011169946 241 AQAPIMAAVVTALERFDLNNLKDAFERAEKVDLSVFeaEK-IE-------------YKKTPTGFIIKNSS-----EE--- 298 Methanococcus m...
WP_010877510 238 AQPPLVAAMVRALEEFEPSEIRDAIKRKEEF-LRDF--RG-PE-------------VEETPTGFIIKSSS-----LE--- 292 Methanothermoba...
WP_011406503 238 AQAPLIVGMIKGLEKYSPERIQEAFKQKDELYQKLL--DKqLN-------------PQTTPTGFMFKEEEikaevEK--- 299 Methanosphaera ...
WP_011018990 237 VDGPTLAAVKRAFEEFELSSLEARLKELERVYERLK--DE-LD-------------VERTGAGLVFHGVE-----RE--- 292 Methanopyrus ka...
2AEU_A       311 nikKLIEIGFN-----------LLKNYGIITITVAGMPGASKSLRIDLTSRDAERIDDNYIIKAIVESIK 369 Methanocaldococcus jannas...
WP_011169946 299 ---KLIETALK-----------LLENYGIVTITAAGMPGASKNIRIDFCSKDAERISDEYVINAVLNSLK 354 Methanococcus maripaludis
WP_010877510 293 ---DLQGSGYDgdeistalsmiLLSEHGIVTIPAVGMPGASKTLRFDLAARDAGRIEISFLREAIYDAIK 359 Methanothermobacter therm...
WP_011406503 300 ---RGAKVDMDadviatvysmlLIDNYNIITIPAVGMPGASKTVRFDWAAKDSDKLTMDELVSAVCDTFD 366 Methanosphaera stadtmanae
WP_011018990 293 -----VEIGLG-----------LLRRYGIMTITALGYERVDRTLRFNLLTEDAERFGYDRFVEVVKGELS 346 Methanopyrus kandleri
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