Conserved Protein Domain Family
F420_Rv3520c
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TIGR03559: F420_Rv3520c 
probable F420-dependent oxidoreductase, Rv3520c family
Members of this protein family are predicted to be oxidoreductases dependent on coenzyme F420. The family includes a single member in Mycobacterium tuberculosis (Rv3520c/MT3621) but four in Mycobacterium smegmatis. Prediction that this family is F420-dependent is based primarily on Partial Phylogenetic Profiling vs. F420 biosynthesis. [Unknown function, Enzymes of unknown specificity]
Links
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Statistics
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PSSM-Id: 274647
Aligned: 14 rows
Threshold Bit Score: 481.064
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_010907681   9 KLGLQLGYwaAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTL 88  Mycobacterium l...
WP_011595049   2 RIGMGLNY--SGGFAETVDEVADLEKAGLDIAFVPEAYSFDAVSQIGYLAAKTTTLELASGIFQIYTRTPSLTAMTAAGL 79  Rhodococcus
ETB39600       3 RIGIALNY--SGGFHEAVDRVVELEKAGIEVAVVAEAYSFDAISQLGYLAAKTSTVELASGVLPLYIRTPSLLAMTAAGL 80  Mycobacterium a...
WP_011558549   5 RTGIFLSY--AGGFREAVEDVVELEKTGVDIALVAEAYSFDAISQLGYLAAKTSRIELGTGVVPIYVRTPSLLAMTAAGL 82  Mycobacterium
WP_011723361   4 RIGLSINY--AGGFKDVAAEVADLENAGLDIVFVPEAYSFDAVSALGYLAASTQRVELASGILQLYTRTPTLTAMTAAGL 81  Mycobacterium a...
WP_011597031   2 KLGLQLGYwgAQPPANVPELIAAAEAEGFDAVFAAESWGSDAFTPLAWWGSSTRRVRLGTSVVQISARTPTSTAMHALTL 81  Rhodococcus jostii
WP_023840291   2 RIAMSLGY--SGGFEETVSGLADYEKAGLQVVQVAEAYSFDAVSQLGFLAARTSRVEIASGIMQLYTRTPSLIAMTAAGL 79  Frankia sp. CcI6
WP_011593673   2 RVGIAAGYwgSGPPRNVGRMLAEAEALGVDSFWTAETYGSDALTPLAWWGAQTSTIKLGTSVCQMSARTPTALAMAALTL 81  Rhodococcus
WP_011207056   3 KFGLQLGYwmAQPPANAGELVVAAEAAGFDAVFAAESWGSDAFGPLMWWGSRTERVRLGTSVVQLSARTPAATAMHALTL 82  Nocardia farcinica
WP_011031181   2 ELSSPLTY--TGDPRTAADRAAALESAGLDAVWVAEAYGFDSPTIMGYLAARTERMRIGSAVLNVYSRSPALIAQTAAGL 79  Streptomyces

WP_010907681  89 DHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREApVVSDGQHYPLPLTGAGATGLGKALKPITH 168 Mycobacterium l...
WP_011595049  80 DFVSDGRFVMGLGASGPQVIEGFHGVKYDAPLGRTREVVEICRKVWRREK-VEFQGKYYQIPLPAEKGTGLGKPLKIINH 158 Rhodococcus
ETB39600      81 DYVSDGRFRLGIGTSGPQVIEGFHGVPFDAPIGRTREIVEICRMVWRREr-VQYAGRHYQLPLPPDRGTGLGKPLHLINH 159 Mycobacterium a...
WP_011558549  83 DYVSDGRFRLGIGTSGPQVMEGFHGVPFDAPLGRTREVVEICRKVWRREn-VEFDGRYYQIPLPADRGSGLGKPLHLINH 161 Mycobacterium
WP_011723361  82 DYVSDGRFTLGLGASGPQVIEGFHGVPYDAPIGRTREVIEICRQVWRREp-VQHRGKHYTIPLPADRGTGLGKPLKLINS 160 Mycobacterium a...
WP_011597031  82 DHLSGGRAILGLGVSGPQVVEGWYGQPFTKPLARTREYVSIIRKVLSREEpVTSDGPHFPLPYTGAGSTGLGKPLKPITH 161 Rhodococcus jostii
WP_023840291  80 DFVSRGRFTLGIGASGPQVIEGFHGVPYDAPLGRTRETIEICRKVWRREv-LEYHGHHYDIPLTAGRGTGLGKPLKIINR 158 Frankia sp. CcI6
WP_011593673  82 DHLSGGRVIIGIGASGPQVVEGWYGQPYPRPLERTREYIEIMRQVWAREKpVTYSGRHYQLPVQG--GSGLGKPLKSIVH 159 Rhodococcus
WP_011207056  83 DHLSGGRAVLGLGVSGPQVVEGWYGQPFAKPLQRTREYVEIIRKVLAREApVTSDGPHYPLPYTGPGATGLGKPLKPIVH 162 Nocardia farcinica
WP_011031181  80 DALTGGRALLGIGASGPQVVEGWHGRRYDRPLGRTREVIELSRRIWRREv-IEHRG-ITDLPLPPEKGGTLGKPLKLLTH 157 Streptomyces

WP_010907681 169 PLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSP-RMADMYNEWLDEGFARTGArrSREDFEICASAQIVVTEDRAAAF 247 Mycobacterium l...
WP_011595049 159 PVRDRIPIVIASLGPKNVELTAEIAEGWEPIFYHPeKAASVWGEPLAKGKAKRDP--SLGELQVFASPALAIGDDVEHML 236 Rhodococcus
ETB39600     160 PVRERIPISIAALGPKNVELTAEIAEGWQPVFYLPdKAGSIWGEALAAGAAKRDP--ALGPLDVMVHASLAIGDDVDQRL 237 Mycobacterium a...
WP_011558549 162 PVRERIPITIAALGPKNVELTAEIAEGWQPVFFYPeKADAVWGDALRAGYAKRDP--ALGPLDVMVSAALAIGDDVEDRL 239 Mycobacterium
WP_011723361 161 PVRERIPILVAALGPKNVEMAAEIAEGWQPIFYLPeKARDVWGESLAAGRAKRAA--ELGELEIYAGPVLAIGENTEPLR 238 Mycobacterium a...
WP_011597031 162 PLRADIPIWLGAEGPKNVALTAEIADGWLAIYYSP-RLAPMYNEWLDEGFARPGArrSREDFEVAATCQVIVTDDRAAAI 240 Rhodococcus jostii
WP_023840291 159 PVRDRIPIVLAALGPKNVELAAELAEGWMPAFYLPdSADEVWGEAVRAGTAKRDP--ALGTLDVWAGASLAVGDDVTALR 236 Frankia sp. CcI6
WP_011593673 160 PLRGDIPVYMGAEGPKNVALAAEIADGWTPLWFSP-KSDEFYRKALAEGFARDGArrTAEDFEIANVCWLVENDDVEKAA 238 Rhodococcus
WP_011207056 163 PLRADLPIWLGAEGPKNVALTAEIADGWLAIYFAP-RLADMYHGWLDEGFARPGArrTREDFEIAASCQVVITDDPAAEL 241 Nocardia farcinica
WP_011031181 158 PVRDTIPVYVAALGPANVRMTAELADGWLPFLYAPeHAAQVWGPSLAEGAAKRDP--ALGPLAVVAGGLLAVDDDAEAVH 235 Streptomyces

WP_010907681 248 AGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAA-WS 326 Mycobacterium l...
WP_011595049 237 DWVRPGLALYIGGMGAKGKNFYNDLAVRYGYEKEAETIQDLYLSGKKDEAAAAVPDDLVRAVSLIGPESYVAERVAA-FA 315 Rhodococcus
ETB39600     238 AWVKPQLALYIGGMGAKGRNFYHNLATRYGFGEVADRIQELYLSGRKQQAIDLVPDELVRGMSLVGPRGYVAERMAA-FA 316 Mycobacterium a...
WP_011558549 240 QWVKPQLALYIGGMGARGRNFYHNLATRYGFGEVADQIQDLYLSGKKAEAIAAVPDDLVRSVSLIGSKAFVKERLAA-FV 318 Mycobacterium
WP_011723361 239 EFVKPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGDKDGAAKVVPDDLVRDVNLIGSREFVKERVAA-FR 317 Mycobacterium a...
WP_011597031 241 AGLKPITALYVGGMGAPELNFHAQVYTRMGYGEQVEEIGRLFRAGRKDEAAAVVPDEMVTETMIIGNVDEVRADVKR-WA 319 Rhodococcus jostii
WP_023840291 237 DTDRPQLALYMGGMGARGRNFYNDLAHRYGYAAEAKLVQDLYLAGRKEEAAAAVPAGLLERLSLIGPRGWVAERLAV-FA 315 Frankia sp. CcI6
WP_011593673 239 SRLKPTVALYAGGMGAKGANFHNDVFARMGWGEVCAEIQELYLSGRPDLAAQAVPTEMVEDVALIGPADKIIEEIETkWK 318 Rhodococcus
WP_011207056 242 ERMRWIMALYIGGMGAPELNFHAQVYRRMGYDREVDEIGALFQAGKKAEAAAAVPDELILDTAIIGDENHVREQLKV-WE 320 Nocardia farcinica
WP_011031181 236 DLMRPTVALYVGGMGAPGRNFYHDLICSYGYEAAAAAIQEHYLAGRRKEAETAVPAELLARICLAGPEGHVRERVEA-FR 314 Streptomyces

WP_010907681 327 AAGVTMMMVS 336 Mycobacterium leprae
WP_011595049 316 ESGVTTLTVT 325 Rhodococcus
ETB39600     317 ESGVTTLLLS 326 Mycobacterium avium 11-0986
WP_011558549 319 EGGATTLLLQ 328 Mycobacterium
WP_011723361 318 EAGVTTLNVA 327 Mycobacterium avium
WP_011597031 320 DAGVTMLLVS 329 Rhodococcus jostii
WP_023840291 316 ESGVTTLAVN 325 Frankia sp. CcI6
WP_011593673 319 NTCLTTLILG 328 Rhodococcus
WP_011207056 321 AAGVTMMLVS 330 Nocardia farcinica
WP_011031181 315 ESGVTMLNVT 324 Streptomyces
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